Comparison of Vitamin D Levels Between Healthy Individuals and Cancer Patients

Abstract

Objectives: This study aimed to determine whether vitamin D levels differ between cancer patients and non-cancercontrol groups, to determine the differences between the reference values and also to determine the prevalence ofvitamin D deficiency in cancer patients.Methods: Vitamin D levels were examined retrospectively between 2017-2018 in outpatient oncology patients andnon-oncology patients who applied to Mardin State Hospital.Results: A total of 355 patients were examined (157 oncologic patient group and 198 in the control group). The medianage of the oncologic patient group was 55.24 (19-85) and the control group was 55.45 (18-89). The median vitamin Dvalue of the oncology patients was 8.15 ng / mL (≤4.2-33.72) and the control group was 14.39 ng / mL (≤4.2-60.13). Itwas statistically significant that vitamin D levels were lower in the oncology patients when compared with the controlgroup (p<0.001).Conclusion: In this study, vitamin D deficiency was found to be very common in cancer patients (87.3% according toreference value of 20 ng/mL) and vitamin D levels were lower in cancer patients compared to the control group. 10 ng/mL is a suitable reference value for defining vitamin D deficiency in cancer patients.