Algso, Muheb A. S.Kivrak, Arif2025-05-102025-05-1020192585-72901336-907510.1007/s11696-018-0640-22-s2.0-85059934527https://doi.org/10.1007/s11696-018-0640-2https://hdl.handle.net/20.500.14720/13596Kivrak, Arif/0000-0003-4770-2686Pd-catalyzed coupling reactions like the Sonogashira coupling reaction are very useful tools for the formation of new carbon-carbon bonds under mild reaction conditions. Coupling reactions are also used for elaboration of organic compounds in drug and material discovery. Terminal alkynes have a very critical role in Sonogashira coupling reaction. Therefore, design and synthesis of new terminal alkynes are very important for the preparation of organic compounds. In the present study, a novel alkyne 3-ethynyl-2-(thiophen-2-yl)benzo[b]thiophene 13 was synthesized, and it was tested for Sonogashira coupling reaction with different iodoaryl compounds. It was investigated whether our terminal alkyne 13 having a special construction might be a useful precursor for the synthesis of potentially active organic molecules.eninfo:eu-repo/semantics/closedAccessAlkynesBenzothiophenesSonogashira Coupling ReactionC-C Bond Formation ReactionsArticle734Q3Q3977985WOS:000463784900020