Alpaslan, DuyguOlak, TuluTuran, AbdullahErsen Dudu, TubaAktas, Nahit2025-05-102025-05-1020210366-63522585-729010.1007/s11696-021-01760-22-s2.0-85109259803https://doi.org/10.1007/s11696-021-01760-2https://hdl.handle.net/20.500.14720/7933Ersen Dudu, Tuba/0000-0001-5564-2834; Turan, Abdullah/0000-0003-3330-4468; Alpaslan, Duygu/0000-0002-6007-3397In this study, six different organo-hydrogels containing agar-glycerol (AG)-based garlic oil (GO) were synthesized using two different crosslinkers (N,N, methylenebisacrylamide (MBA), glutaraldehyde (GA)) to ensure the controlled release of ceftriaxone (Ce) and carboplatin (Cp). Synthesized organo-hydrogels were characterized by FT-IR. Afterward, swelling behaviors were investigated in DI, tap water, ethanol, acetone, ethanol/DI water (1:1), acetone/DI water (1:1) and gasoline environments and different pH. As a result of hemolysis, blood clotting and antioxidant analysis, organo-hydrogels have been shown to have blood compatibility and antioxidant properties. Ce and Cp release properties of the prepared organo-hydrogels were also determined. The highest Ce release rate was obtained to be 37.8% for p (AG-g-GO)(3) at pH 8.0 after 7 days. However, the highest Cp release rate was found to be 95.4% for p (AG-g-GO)(3) at pH 7.4 after 1 day.eninfo:eu-repo/semantics/openAccessOrgano-HydrogelAgarGarlic OilCeftriaxoneCarboplatinArticle7511N/AQ35759577234230754WOS:000669179400001