Yigit, AydinYardim, YavuzCelebi, MetinLevent, AbdulkadirSenturk, Zuhre2025-05-102025-05-1020160039-91401873-357310.1016/j.talanta.2016.05.0462-s2.0-84970027928https://doi.org/10.1016/j.talanta.2016.05.046https://hdl.handle.net/20.500.14720/15380Senturk, Zuhre/0000-0002-0356-9345; Levent, Abdulkadir/0000-0001-5792-419X; Yardim, Yavuz/0000-0002-9587-096X; Celebi, Metin/0000-0003-1475-8878A graphene-Nafion composite film was fabricated on the glassy carbon electrode (GR-NF/GCE), and used for simultaneous determination of paracetamol (PAR), aspirin (ASA) and caffeine (CAF). The electrochemical behaviors of PAR, ASA and CAF were investigated by cyclic voltammetry and square-wave adsorptive anodic stripping voltammetry. By using stripping one for simultaneous determination of PAR, ASA and CAF, their electrochemical oxidation peaks appeared at +0.64,1.04 and 1.44 V, and good linear current responses were obtained with the detection limits of 18 ng mL(-1) (1.2 x 10(-9) M), 11.7 ng mL(-1) (6.5 x 10(-8) M) and 7.3 ng mL(-1) (3.8 x 10(-8) M), respectively. Finally, the proposed electrochemical sensor was successfully applied for quantifying PAR, ASA and CAF in commercial tablet formulations. (C) 2016 Elsevier B.V. All rights reserved.eninfo:eu-repo/semantics/closedAccessParacetamolAspirinCaffeineGraphene-Nafion Composite Film Modified Glassy Carbon ElectrodePharmaceutical FormulationArticle158Q1Q1212927343573WOS:000379370400004