Dogan, A.Dönmez, F.Battal, A.2025-05-102025-05-1020229783031077531978303107752410.1007/978-3-031-07753-1_362-s2.0-85161547335https://doi.org/10.1007/978-3-031-07753-1_36https://hdl.handle.net/20.500.14720/3070Urtica dioica L., known as nettle, is a herbaceous, perennial plant, belonging to Urticaceae family. This chapter covers description and distribution of the plant. Additionally, its chemical composition and traditional use were presented in detail. The in vitro and in vivo activities of nettle extracts (root, leave, and seed) such as antimicrobial, antiviral, antioxidant, anti-inflammatory, antidiabetic, hepatoprotective, hypotensive, and anticancer have been highlighted via its rich phytochemical composition. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.eninfo:eu-repo/semantics/closedAccessAntioxidantNettle PlantPhytochemical CompositionUrtica DioicaBook PartN/AN/A553563