Karahan, FatihBasi, ZehraKeskin, ErtugrulPinar, Pinar TalayYardim, YavuzSenturk, Zuhre2025-05-102025-05-1020202365-654910.1002/slct.2020029212-s2.0-85096010449https://doi.org/10.1002/slct.202002921https://hdl.handle.net/20.500.14720/6843Senturk, Zuhre/0000-0002-0356-9345; Yardim, Yavuz/0000-0002-9587-096XIn this article, a simple, fast and inexpensive methodology has been developed for the determination of fluoroquinolone class antibiotic norfloxacin (NFX) in anionic surfactant media (sodium dodecyl sulphate, SDS) using an anodically pretreated boron-doped diamond (APT-BDD) electrode. Cyclic voltammetric studies showed that the NFX gave an irreversible and adsorption controlled anodic oxidation signal at a potential of about +1.32 V on the APT-BDD electrode. The effects of parameters such as the electrode pre-treatment procedure, SDS concentration, and instrumental variables on the electrochemical sensitivity of NFX were evaluated. Under optimized conditions, the linearity was achieved in the range of 0.05 to 4.0 mu g mL(-1) (1.57x10(-7)-1.25x10(-5) mol L-1), with a detection limit of 0.013 mu g mL(-1) (4.07x10(-8) mol L-1) by using square-wave adsorptive stripping voltammetry (SW-AdSV). The feasibility of the developed approach for the quantification of NFX in urine samples was tested.eninfo:eu-repo/semantics/closedAccessNorfloxacinVoltammetryBoron-Doped Diamond ElectrodeSurfactantsUrine SamplesArticle542Q3Q31286212868WOS:000591276200003