Erdem, A.Genc, H.Sen, N.Kilincarslan, R.Erdem, E.2025-05-102025-05-1020170034-775210.37358/rc.17.1.54072-s2.0-85019467637https://doi.org/10.37358/rc.17.1.5407https://hdl.handle.net/20.500.14720/5031We report some novel pyrazole derivatives taking 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione, 1. For this, 4-phenylcarbonyl-5-phenyl-2,3-dihydro-2,3-furandione, 1 was reacted with benzaldehyde(2-or 4-fluorophenyl)hydrazone to give 4-benzoyl-1-(2-or 4-fluorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid 2a,b. Pyrazol derivative containing 2-fluorophenyl group 2a was converted into carboxylic chloride derivative 3a by thionyl chloride and then the compound 4a was obtained from reaction ammonia with compound 3a. In the next step, 4-benzoyl-1-(2-fluorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid 2a was reacted with MeOH/H2SO4, EtOH/H2SO4, 2-nitrophenylhydrazine and 3-nitrophenylydrazine to give 5a,b and 6a,b pyrazol derivatives, respectively. The structures regarding all compounds synthesized were determined by the IR, NMR and elemental analysis method.eninfo:eu-repo/semantics/openAccess2,3-FurandioneHydrazonesNucleophilesPyrazole-3-Carboxylic AcidArticle681N/AN/A143146WOS:000395499200031