Arici, Omruye OzokCaglar, AykutNajri, Bassam A.Aktas, NahitKivrak, ArifKivrak, Hilal2025-05-102025-05-1020252196-735010.1002/admi.2024007072-s2.0-105002114447https://doi.org/10.1002/admi.202400707https://hdl.handle.net/20.500.14720/11169Kivrak, Arif/0000-0003-4770-2686In this work, a bimetallic Ru-Co catalyst based on carbon nanotubes (Ru-Co/CNT) with a Ru to Co ratio of 95:5 is developed. The catalyst, featuring a total metal loading of 3% on the CNTs, is synthesized using the NaBH4 reduction method. Several analytical analyses are used to detect the properties of the Ru-Co/CNT catalyst. X-ray diffraction (XRD) provides information on crystal structures of the catalysts, high-resolution transmission electron microscopy (HR-TEM) reveals particle size and distribution, inductively coupled plasma mass spectrometry (ICP-MS) measures the elemental composition, and X-ray photoelectron spectroscopy (XPS) use to investigate the chemical oxidation states. In addition, thermal techniques including temperature-programmed reduction (TPR), temperature-programmed oxidation (TPO), and temperature-programmed desorption (TPD) are used to recognize the active sites on the catalyst's surface and the acidity. Then, the Ru-Co/CNT catalyst is applied as a sensor for isoleucine amino acid for the first time. It shows high performance with these parameters, sensitivity (0.002 mA cm-2 mm), LOD - limit of detection (0.04 mu m), and LOQ - limit of quantification (0.12 mu m). Moreover, the interferences of common serum blood including (D-glucose, uric acid, ascorbic acid, and L-tryptophan) are studied. The findings indicated that the sensor is applicable to work in complex biological systems.eninfo:eu-repo/semantics/openAccessBimetallicCarbon NanotubesElectrochemical SensorIsoleucineRuthenium-Cobalt CatalystArticle127Q2Q1WOS:001389863800001