Jafarova, ShahlaAydin, TubaIsayev, JavanshirSaglamtas, RuyaOzgokce, FevziKazaz, CavitCakir, Ahmet2025-05-102025-05-1020251612-18721612-188010.1002/cbdv.2024020132-s2.0-85219612995https://doi.org/10.1002/cbdv.202402013https://hdl.handle.net/20.500.14720/12384Jafarova, Shahla/0000-0002-8379-9529; Aydin, Tuba/0000-0002-7653-6480Onobrychis Adans. species, known as 'sainfoin,' are commercially valuable plants cultivated to produce high-protein animal feed. In this study, the ethanol extract of Onobrychis buhseana Boiss., which is widely distributed in Azerbaijan, was subjected to silica gel column and thin-layer chromatography for the first time, leading to the isolation of a new natural hydroquinone oligomer, named buhseanol (1), along with two known compounds, beta-arbutin (2) and an inositol derivative (3). The chemical structure of buhseanol (1) was characterized by proton nuclear magnetic resonance (1H-NMR), carbon-13 NMR, Attached Proton Test NMR, and liquid chromatography-tandem mass spectrometry. Buhseanol (1), beta-arbutin (2), and the ethanol extract were evaluated for their anti-Alzheimer's, anti-glaucoma, and anti-diabetic effects, with both the extract and buhseanol (1) potentially showing these activities. The inositol derivative (3) did not exhibit any of these activities.eninfo:eu-repo/semantics/closedAccessBeta-ArbutinBuhseanolEnzyme InhibitionOnobrychis Buhseana BoissSainfoinArticleQ3Q439946108WOS:001432807500001