Yigit, AydinYardim, YavuzSenturk, Zuhre2025-05-102025-05-1020201061-93481608-319910.1134/S10619348200501842-s2.0-85084921137https://doi.org/10.1134/S1061934820050184https://hdl.handle.net/20.500.14720/6041Senturk, Zuhre/0000-0002-0356-9345; Yardim, Yavuz/0000-0002-9587-096XIn the present study, an electroanalytical method for the determination of hesperidin using adsorptive stripping voltammetry at an unmodified boron-doped diamond (BDD) electrode is presented. In cyclic voltammetry, the compound showed one irreversible and adsorption-controlled oxidation peak, resulting in the formation of a couple with a reduction and re-oxidation wave at less positive potentials. Using square-wave stripping mode, the observed anodic peak current in 0.1 M perchloric acid solution at +0.90 V (vs. Ag/AgCl) (after 30 s accumulations at a fixed potential of +0.4 V) increased linearly from 2.5 to 70 mu g/mL (4.09 x 10(-6)-1.15 x 10(-4) M). A detection limit of 0.7 mu g/mL (1.2 x 10(-6) M) and relative standard deviation of 8.2% for the concentration of 2.5 mu g/mL (n = 10) were observed. To evaluate the practical applicability of the BDD electrode, it was used for the quantification of hesperidin in the commercial dietary supplement formulations.eninfo:eu-repo/semantics/closedAccessHesperidinBoron-Doped Diamond ElectrodeSquare-Wave Adsorptive Stripping VoltammetryDietary SupplementArticle755Q4Q3653661WOS:000530804800014