Yenidede, DuyguGumus, SelcukGumus, Aysegul2025-05-102025-05-1020161300-05271303-613010.3906/kim-1512-312-s2.0-84975722454https://doi.org/10.3906/kim-1512-31https://search.trdizin.gov.tr/en/yayin/detay/256127/isoquinoline-substituted-triazole-and-pyran-derivatives-synthesis-andcomputational-studieshttps://hdl.handle.net/20.500.14720/20313Gumus, Aysegul/0000-0002-1613-7074; Gumus, Selcuk/0000-0002-8628-8943The one-pot synthesis of novel 1,4-disubstituted 1,2,3-triazoles from isoquinoline-substituted homopropargyl alcohol backbone is described (42%-88% yields). A ring closing metathesis reaction and an intramolecular Pauson-Khand reaction of enyne system derived from a homopropargyl alcohol backbone to afford the corresponding isoquinoline-substituted dihydropyran and cyclopentenone-pyran, respectively, are also described (54% and 78% yields). Information about the structural, electronic, and physico-chemical properties of the novel compounds, obtained by density functional theory application, is also reported.eninfo:eu-repo/semantics/openAccessIsoquinoline1,2,3-TriazolesRing Closing Metathesis ReactionPauson-Khand ReactionArticle404Q4Q3655666256127WOS:000384977600011