Akdag, SerkanAkyol, AytacAsker, MuntecepOzturk, FatihGumrukcuoglu, Hasan Ali2025-05-102025-05-1020161734-93381897-429510.5114/aic.2016.616442-s2.0-84983365316https://doi.org/10.5114/aic.2016.61644https://hdl.handle.net/20.500.14720/15376Gumrukcuoglu, Hasan Ali/0000-0002-5972-9870Introduction: Recently, platelet-to-lymphocyte ratio (PLR) has emerged as a significant inflammatory marker and a novel predictor of major adverse consequences in cardiovascular disease. Aim: In this study, we aimed to explore the relationship between PLR and coronary collateral circulation (CCC) in patients with non-ST elevation myocardial infarction (NSTEMI). Material and methods: Clinical and laboratory data of 386 patients who underwent coronary angiography were evaluated retrospectively. The patients were classified into 2 groups as follows: poor CCC (group 0-1: Rentrop grades 0-1) and good CCC (group 2: Rentrop grades 2-3). The PLR was calculated from the complete blood count. Results: The PLR values of the patients with poor CCC were significantly higher than those of patients with good CCC (153.9 +/- 26.6 vs. 129.8 +/- 23.5, p < 0.001). In the multiple logistic regression tests, PLR (odds ratio: 1.51, 95% confidence interval: 1.27-1.74; p < 0.001) and hs-CRP (odds ratio: 1.56, 95% CI: 1.03-2.11; p < 0.001) were found to be independent predictors of poor CCC. The receiver operating characteristic (ROC) curve analysis yielded a cutoff value of 140.5 for PLR to predict poor CCC with 79% sensitivity and 71% specificity, with the area under the ROC curve being 0.792 (95% CI: 0.721-0.864). Conclusions: Our study revealed that high PLR is independently associated with poor coronary collateral circulation in patients with NSTEMI.eninfo:eu-repo/semantics/openAccessAngiographyCoronary Artery DiseaseCardiologyArticle123Q4Q322423027625685WOS:000382411600006