Demirok, ASimsek, SÇinal, AYasar, T2025-05-102025-05-1019981120-672110.1177/1120672198008003062-s2.0-0031721621https://doi.org/10.1177/112067219800800306https://hdl.handle.net/20.500.14720/8169Demirok, Ahmet/0000-0001-8197-2458Purpose. To investigate the effectiveness of intraoperative mitomycin C in pterygium surgery. Methods. The effectiveness of intraoperatively administered mitomycin C and the occurrence of postoperative complications were evaluated in 17 patients with two recurrences of pterygium. The authors employed the "bare-sclera technique" and placed a sterile sponge soaked in a 0.02% mitomycin C solution intraoperatively in the episcleral space for 3 minutes. The control group (15 patients) underwent only surgical excision. Patients were followed for 21 to 30 months. Results. The pterygium recurred in one (5.9%) of the 17 patients in group 1 and in six (40%) of the 15 controls. Statistical analysis using Fisher's exact test showed a significant (p=0.027) reduction of recurrences of pterygium in the group treated intraoperatively with mitomycin C. No serious complications or side effects arose during the follow-up period. Conclusions. Mitomycin C administered intraoperatively can be considered an effective treatment to improve the success rate after surgical excision.eninfo:eu-repo/semantics/closedAccessPterygiumMitomycin CRecurrenceArticle83Q4Q21531569793768WOS:000077895200006