Köşüş, A.Köşüş, N.Güler, A.Çapar, M.2025-05-102025-05-1020101304-388910.29333/ejgm/828672-s2.0-79551666868https://doi.org/10.29333/ejgm/82867https://hdl.handle.net/20.500.14720/6609Aim: The aim of this study was to compare the effect of Rifamycin SV application to subcutaneous tissue for prevention of post-caesarean wound infection with a traditional method used for preoperative antisepsis of skin; povidone-iodine and also to calculate cost of the treatment. Method: In this randomized prospective study, 1272 women were divided into two groups. Povidone-iodine was used for preoperative antisepsis and after closure of the skin in the first group. In the second group povidone-iodine was used in the same way but also subcutaneous tissue was irrigated with Rifamycin SV before closure of subcutaneous tissue. Result: Surgical site infection (SSI) was developed in 12 of 600 patients in the first group. All of them were superficial incisional SSI. In 2 cases wound was opened up to fascia. The overall rate of wound infection with pus was 2%. Total cost of 12 patients with SSI was $5386.In the 2nd group, SSI wasn't develop in any of the 596 patients. Total cost of the rifamycin SV used for washing of subcutaneous tissue was $876.12. Conclusion: Rifamycin SV application to subcutaneous tissue during cesarian effectively prevents SSI. It decreases both cost and morbidity caused by wound infection.trinfo:eu-repo/semantics/openAccessCesarian SectionPovidone-IodineRifamycinSurgical Site InfectionArticle73N/AN/A269276