Elci, ErkanKaya, CihanCim, NumanYildizhan, RecepElci, Gulhan Gunes2025-05-102025-05-1020170951-35901473-076610.1080/09513590.2016.12038932-s2.0-84978496425https://doi.org/10.1080/09513590.2016.1203893https://hdl.handle.net/20.500.14720/11917Cim, Numan/0000-0003-0983-3204; Elci, Erkan/0000-0002-9792-6592; Kaya, Cihan/0000-0003-4175-7694Objective: To compare cardiac risk markers such as asymmetric dimethyl arginine (ADMA), C-reactive protein (CRP), homocystein (Hcy), plasminogen activator inhibitor-1 (PAI-1), vascular endothelial growth factor (VEGF), angiopoietin-related growth factor 6 (ANGPTL6) in obese and non-obese patients with polycystic ovary syndrome (PCOS). Study design: Thirty obese (BMI>30kg/m(2)) and 30 non-obese (BMI<30kg/m(2)) patients diagnosed with PCOS and 30 age-matched healthy controls were included in the study. The ages of subjects were varying between 18 and 30 years. Serum ADMA, CRP, Hcy, PAI-1, VEGF and ANGPTL6 levels were analyzed for each subject. Results: Serum ADMA, CRP, Hcy, PAI-1, VEGF and ANGPTL6 levels were significantly elevated in obese and non-obese women with PCOS in comparison to control subjects (p<0.05). This elevation was more obvious in the obese PCOS group than in the other group. Conclusions: Cardiovascular risk markers such as ADMA, CRP, Hcy, PAI-1, VEGF and ANGPTL6 levels are elevated in women with PCOS.eninfo:eu-repo/semantics/closedAccessAngiopoietin-Related Growth FactorCardiovascular Diagnostic TechnicObesityPolycystic Ovary SyndromeArticle331Q3Q3434727425379WOS:000395010300010