Tolunay, H.E.Boza, B.Varlı, B.2025-05-102025-05-1020181301-088310.5505/ejm.2018.146222-s2.0-85045976158https://doi.org/10.5505/ejm.2018.14622https://hdl.handle.net/20.500.14720/5174Premature ovarian failure was defined as the cut-off of menstrual period for at least 4-6 months before 40 years of age, and FSH values measured over a month were over 40 IU/L. Although etiology is not fully understood, it is thought that genetic, immunological and environmental factors can play a role. Nowadays, translational and deletion in the critical regions (Xq13-26) on the X chromosome are defined in the developmental light in the genetic area. New approaches have been developed in clinical follow-up and treatment in recent years. It has been reported that caution should be taken in the follow-up, especially in terms of osteoporosis. In this article, recent literature on premature ovarian failure attempted to reveal current genetic etiology of premature ovarian failure. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.eninfo:eu-repo/semantics/openAccessGenetic ReasonsOvarian AgingPremature Ovarian FailureArticle232N/AQ4135140271971