Sayarlioglu, HayriyeErkoc, RebaSayarliogin, MehmetDogan, EkremSoyoral, Yasemin2025-05-102025-05-1020060172-81721437-160X10.1007/s00296-006-0188-22-s2.0-33846114183https://doi.org/10.1007/s00296-006-0188-2https://hdl.handle.net/20.500.14720/6776Reha, Erkoc/0009-0001-7230-8843; Sayarlioglu, Mehmet/0000-0001-6214-1974Secondary amyloidosis is a well-known complication of certain familial Mediterranean fever (FMF). We presented three Turkish patients with FMF and biopsy proven amyloidosis. These patients were treated with colchicine 1.5 mg/day. They have experienced five to six peritonitis attacks with fever within 1 year. On admission, the laboratory test results were as follows: serum creatinine 2.3, 0.6, and 0.5 mg/dl; albumin 4.2, 1.9, and 1.8 g/dl; and urinary protein excretion 4, 15, and 10 g/day, respectively. All the patients were started azathioprine (AZA) 100 mg/day and attacks were completely stopped. Laboratory findings were as follows after I year of AZA treatment: serum creatinine 1, 0.8, and 0.6 mg/dl; albumin 4.3, 3, and 3.5 g/dl; and urinary protein excretion 3, 8, and 1.5 g/day, respectively. Treatment with azathioprine in addition to colchicine could ameliorate the nephrotic syndrome and control the attacks very effectively in these cases.eninfo:eu-repo/semantics/closedAccessFmfSecondary AmyloidosisAzathioprineArticle272Q2Q219719916944160WOS:000243226400015