Cegin, Muhammed BilalAslan, MehmetGoktas, UgurIsik, YaseminSoyoral, LokmanAksoy, NurtenKati, Ismail2025-05-102025-05-1020160030-99822-s2.0-84969960086https://hdl.handle.net/20.500.14720/16508Objectives: To investigate the effects of occupational exposure to anaesthetic gases on myeloperoxidase activity, oxidative and antioxidative parameters in operating room personnel. Methods: The cross-sectional study was conducted at Yuzuncu Yil University, Van, Turkey, in May 2011, and comprised equal number of operating room and non-operating room personnel. Serum myeloperoxidase activity, sulfhydryl group levels, lipid hydroperoxide levels and catalase activity were determined. SPSS 11 was used for data analysis. Results: There were 64 subjects; 32(50%) each in the two groups. Myeloperoxidase activity and lipid hydroperoxide levels were significantly higher in operating room personnel than in the non-operating room personnel (p<0.001; p<0.001), while catalase activity and sulfhydryl group levels were significantly lower (p<0.009; p<0.003). Catalase activity negatively correlated with lipid hydroperoxide levels in operating room personnel (r=-0.293; p=0.018). Myeloperoxidase activity negatively correlated with sulfhydryl group levels in operating room personnel (r=-0.267; p=0.031). Conclusions: Operating roompersonnel exhibited higher oxidative stress, which may be due to the oxidative effect of anaesthetic gases.eninfo:eu-repo/semantics/closedAccessAnaesthetic GasesMyeloperoxidase ActivityOccupational ExposureOxidative StressSulfhydryl GroupsArticle666Q4Q366667027339566WOS:000376687000009