Simsek, H.Sahin, M.Gunes, Y.Akdag, S.Akil, M. A.Akyol, A.Yaman, M.2025-05-102025-05-1020131128-36022-s2.0-84878564640https://hdl.handle.net/20.500.14720/4028Gunes, Yilmaz/0000-0003-3817-851X; Gumrukcuoglu, Hasan Ali/0000-0002-5972-9870BACKGROUND: To improve clinical outcomes, noninvasive imaging modalities have been proposed to measure and monitor atherosclerosis. Endothelial dysfunction is considered the first stage in the development of atherosclerosis. Brachial artery flow-mediated dilatation (FMD) has been impaired in patients with coronary slow flow (CSF). Recently, color M-mode derived propagation velocity of descending thoracic aorta (aortic propagation velocity-AVP) was shown to be an ultrasonographic marker for atherosclerosis. AIM: To assess endothelial function in patients with CSF and the correlation of AVP with FMD. MATERIALS AND METHODS: FMD and AVP were measured in 90 patients with CSF and 39 patients having normal coronary arteries (NCA) detected by coronary angiography. RESULTS: Compared to patients with normal coronary arteries patients having CSF had significantly lower AVP (39.1 +/- 8.4 vs. 53.7 +/- 12.7 cm/s, p < 0.001) and FMD (5.6 +/- 3.2 vs. 17.6 +/- 4.4 %, p < 0.001) measurements. There were significant correlations between AVP and FMD (r = 0.524, p < 0.001). CONCLUSIONS: Transthoracic echocardio-graphic determination of color M-mode propagation velocity of descending aorta is a simple practical method and correlates well with coronary slow flow and brachial endothelial function.eninfo:eu-repo/semantics/closedAccessColor M-ModeCoronary Slow FlowEndothelial FunctionFlow Mediated DilatationPropagation VelocityArticle175Q2Q268969323543453WOS:000319225900014