Sayin, RefahSoyoral, Yasemin UsulErkoc, Reha2025-05-102025-05-1020110886-022X1525-604910.3109/0886022X.2011.5738932-s2.0-79956283654https://doi.org/10.3109/0886022X.2011.573893https://hdl.handle.net/20.500.14720/1742Reha, Erkoc/0009-0001-7230-8843Background: Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy. Objectives: In this case report, we aimed to present a renal transplant patient with polyneuropathy (PNP) due to the use of CsA and with improvement when switched to rapamycin. Methods: In electromyography, axonal sensory PNP was detected. CsA was stopped and rapamycin was begun. Results: His complaints rapidly improved after using rapamycin. Conclusions: Patients using CsA should be closely monitored for peripheral neuropathy and in case of toxicity, alternative immunosuppressive agents should be considered.eninfo:eu-repo/semantics/closedAccessCyclosporine APolyneuropathyRenal TransplantationCalcineurin InhibitorElectromyographyArticle335Q2Q252853021545310WOS:000290670300012