Sener, AhmetTozlu, IsrafilGenc, HasanBildirici, IshakArisoy, Kadir2025-05-102025-05-1020070022-152X1943-519310.1002/jhet.55704405162-s2.0-36649036632https://doi.org/10.1002/jhet.5570440516https://hdl.handle.net/20.500.14720/12486Bildirici, Ishak/0000-0001-8590-30701,5-Diphenyl-1H-pyrazole-3,4-(dicarboxylic acid-4-ethyl ester 2, obtained from the 4-ethoxycarbonyl-5phenyl-2,3-furandione 1 and N-benzylidene-N'-phenyl hydrazine, was converted via reactions of its acid chloride 3 with various alcohols or N-nucleophiles into the corresponding ester 5 or amide derivatives 6, respectively. In addition, 2 was decarboxylated to give ethyl 1,5-diphenylpyrazole-4-carboxylate 4. Nitrile 7 derivative of 2 was also obtained by dehydration of 6a in a mixture of SOCl2 and DMF. While cyclo condensation reaction of 2 with hydrazine hydrate leads to the formation of pyrazolo[3,4d]pyridazine-4,7-dione 8, the reaction of 3 with anhydrous hydrazine provided a new bis pyrazole derivative 9.eninfo:eu-repo/semantics/closedAccessArticle445Q2Q210771081WOS:000249508400016