Korkmaz, M.O.Sayhan, H.Guven, M.2025-05-102025-05-1020190379-528410.15537/smj.2019.9.244852-s2.0-85072199117https://doi.org/10.15537/smj.2019.9.24485https://hdl.handle.net/20.500.14720/5379Objectives: To evaluate the effectiveness of sugammadex in reducing or eliminating postoperative agitation levels, early respiratory complications and nausea/vomiting in children undergoing adenotonsillectomy. Methods: A total of 70 patients (age range: 5-13 years) who underwent an adenotonsillectomy in the Otolaryngology Clinic, Sakarya University, Sakarya, Turkey between May 2015 and September 2017 were included in the study. The patients were randomized into a sugammadex group (Group S) and a neostigmine + atropine (Group N); each group contained 35 patients. Time to extubation, postoperative agitation levels, and early postoperative complications were evaluated and recorded. Data from both groups were statistically evaluated and compared. Results: The time to extubation was significantly shorter in Group S than Group N (p<0.05). Agitation scores during recovery were significantly lower in Group S than Group N (p<0.05). More complications were observed in Group N than in Group S; the number of patients seen coughing and experiencing nausea/vomiting in Group S was statistically significantly lower (p<0.05). Conclusion: This study demonstrated that the use of sugammadex results in less time to recovery and less agitation in comparison to conventional administration of neostigmine + atropine in the reversal of neuromuscular blocking after adenotonsillectomy. © 2019 Saudi Arabian Armed Forces Hospital. All rights reserved.eninfo:eu-repo/semantics/openAccessArticle409Q3Q290791331522218