Cicek, VedatYavuz, SametSaylik, FaysalTaslicukur, SolenOz, AhmetBabaoglu, MertCinar, Tufan2025-05-102025-05-1020240034-83762564-889610.24875/RIC.23000290https://doi.org/10.24875/RIC.23000290https://hdl.handle.net/20.500.14720/10954Babaoglu, Mert/0000-0003-4544-9584Background: Pan-immuno-inflammation value (PIV) is a new and comprehensive index that reflects both the immune response and systemic inflammation in the body. Objective: The aim of this study was to investigate the prognostic relevance of PIV in predicting in-hospital mortality in acute pulmonary embolism (PE) patients and to compare it with the well-known risk scoring system, PE severity index (PESI), which is commonly used for a short-term mortality prediction in such patients. Methods: In total, 373 acute PE patients diagnosed with contrast-enhanced computed tomography were included in the study. Detailed cardiac evaluation of each patient was performed and PESI and PIV were calculated. Results: In total, 60 patients died during their hospital stay. The multivariable logistic regression analysis revealed that baseline heart rate, N-terminal pro-B-type natriuretic peptide, lactate dehydrogenase, PIV, and PESI were independent risk factors for in-hospital mortality in acute PE patients. When comparing with PESI, PIV was non-inferior in terms of predicting the survival status in patients with acute PE. Conclusion: In our study, we found that the PIV was statistically significant in predicting in-hospital mortality in acute PE patients and was non-inferior to the PESI. (REV INVEST CLIN. [AHEAD OF PRINT])eninfo:eu-repo/semantics/openAccessPan-Immuno-Inflammation ValueAcute Pulmonary EmbolismPulmonary Embolism Severity IndexIn-Hospital Mortality.Article762Q4Q238359843WOS:001163912100001