Talay Pinar, PinarAli, Hoshyar SaadiAbdullah, Abdullah AbdulwahedYardim, YavuzSenturk, Zuhre2025-05-102025-05-1020182630-63441309-080110.12991/jrp.2018.882-s2.0-85056599771https://doi.org/10.12991/jrp.2018.88https://search.trdizin.gov.tr/en/yayin/detay/370953/electroanalytical-determination-of-salbutamol-in-pharmaceutical-formulations-using-cathodicallypretreated-boron-doped-diamond-electrodehttps://hdl.handle.net/20.500.14720/20252Ali, Hoshyar/0000-0002-9138-485X; Senturk, Zuhre/0000-0002-0356-9345; Yardim, Yavuz/0000-0002-9587-096XThis paper examined for the first time the possibilities of the usage of the cathodically pretreated borondoped diamond (CPT-BDD) electrode for the redox behavior of salbutamol (SAL) using cyclic and adsorptive stripping voltammetry. The cyclic voltammograms showed an irreversible and adsorption-controlled oxidation peak at about +1.0 V in the Britton-Robinson (BR) buffer (pH 9.0) solution. Under the optimized experimental condition, using square-wave adsorptive stripping mode, the compound yielded a well-defined voltammetric response in BR buffer, pH 9.0 at +0.95 V (vs. Ag/AgCl) (after 30 s accumulation at an open circuit condition). A linear calibration graph was obtained in the concentration range of 4.15 to 83 mu g mL(-1) (1.73x10(-5) -3.47x10(-4) M). A detection limit of 1.21 mu g mL(-1) (5.06x10(-6) M) was observed. The suggested method was also applied to the determination of SAL in the drug formulations.eninfo:eu-repo/semantics/openAccessSalbutamolBoron-Doped Diamond ElectrodeSquare-Wave Adsorptive Stripping VoltammetryPharmaceutical FormulationsArticle223N/AQ4460468370953WOS:000445922100015