Talay Pınar, P.Ali, H.S.Abdullah, A.A.Yardim, Y.Şentürk, Z.2025-05-102025-05-1020181309-080110.12991/jrp.2018.882-s2.0-85056599771https://doi.org/10.12991/jrp.2018.88https://search.trdizin.gov.tr/en/yayin/detay/370953/electroanalytical-determination-of-salbutamol-in-pharmaceutical-formulations-using-cathodicallypretreated-boron-doped-diamond-electrodeThis paper examined for the first time the possibilities of the usage of the cathodically pretreated boron-doped diamond (CPT-BDD) electrode for the redox behavior of salbutamol (SAL) using cyclic and adsorptive stripping voltammetry. The cyclic voltammograms showed an irreversible and adsorption-controlled oxidation peak at about +1.0 V in the Britton-Robinson (BR) buffer (pH 9.0) solution. Under the optimized experimental condition, using square-wave adsorptive stripping mode, the compound yielded a well-defined voltammetric response in BR buffer, pH 9.0 at +0.95 V (vs. Ag/AgCl) (after 30 s accumulation at an open circuit condition). A linear calibration graph was obtained in the concentration range of 4.15 to 83 μg mL-1 (1.73x10-5-3.47x10-4 M). A detection limit of 1.21 μg mL-1 (5.06x10-6 M) was observed. The suggested method was also applied to the determination of SAL in the drug formulations. © 2018 Elsevier B.V., All rights reserved.eninfo:eu-repo/semantics/openAccessBoron-Doped Diamond ElectrodePharmaceutical FormulationsSalbutamolSquare-Wave Adsorptive Stripping VoltammetryArticle223N/AN/A460468370953WOS:000445922100015