Eski, FundaKurt, SerdalMis, Leyla2025-05-102025-05-1020222602-369510.47748/tjvr.1069768https://doi.org/10.47748/tjvr.1069768https://search.trdizin.gov.tr/en/yayin/detay/512090/monitoring-of-oxidative-stress-and-tnf-a-status-during-the-healing-process-in-hair-goats-with-metritishttps://hdl.handle.net/20.500.14720/19280Objective: This study aimed to monitor oxidative stress parameters including total antioxidant status\r(TAS) and total oxidant status (TOS), and tumor necrosis factor-alpha (TNF-α) level during the healing\rprocess in hair goats with metritis.\rMaterials and Methods: This study was carried out on a total of 25 hair goats with metritis (n=10; Group\r1) and healthy (n=15; Group 2). The beginning of the study was accepted as day 0. In both Group 1 and\rGroup 2, blood samples were collected on days 0 (first measurement day), 14 (second measurement day)\rand 28 (third measurement day) of the study for TAS, TOS and TNF-α analyzes. In addition, oxidative\rstress index (OSI) was calculated using TAS and TOS values.\rResults: It was found that TAS level decreased in Group 1 compared to Group 2 at the first measurement\rday (p<0.05). However, TOS, OSI and TNF-α levels increased in Group 1 compared to Group 2 (p<0.01).\rAt the second measurement day, TOS and OSI values were higher in Group 1 than Group 2 (p<0.05).\rConclusion: In conclusion, the antioxidant system weakened, oxidative stress and TNF-α levels increased\rin animals with metritis compared to healthy animals. However, at the third measurement time, all\rparameters became similar between groups.eninfo:eu-repo/semantics/openAccessHalk Ve Çevre SağlığıSağlık Bilimleri Ve HizmetleriİmmünolojiVeterinerlikArticle61N/AN/A1518512090