Kadı, G.Özlek, E.Saed, Y.2025-05-102025-05-1020222008-210X10.34172/joddd.2022.0362-s2.0-85151472341https://doi.org/10.34172/joddd.2022.036https://hdl.handle.net/20.500.14720/2996Background. The purpose of this study was to assess the push-out bond strength of calcium-silicate and silicone based root canal sealers in bulk and with main cone. Methods. Roots (n = 48) randomly divided into 4 groups (n = 12) according to the obturation protocol; (1) iRoot SP in bulk; (2) iRoot SP with gutta-percha; (3) GuttaFlow Bioseal in bulk; (4) GuttaFlow Bioseal with gutta-percha. Six horizontal sections were obtained from each root (n = 72). Effect of sealers on bond strength was statistically significant (P < 0.05). Results. Highest mean value was obtained in iRoot-Bulk group and lowest in GuttaFlow Bioseal-GP group. Both iRoot SP groups had significantly higher bond strength values than both GuttaFlow Bioseal groups (P < 0.05). There was no significant difference between iRoot-GP and iRoot-Bulk groups (P = 0.603) also GuttaFlow Bioseal-GP and GuttaFlow Bioseal-Bulk groups (P = 0.684). Conclusion. Based on findings, using calcium silicate-based sealer in bulk can be also suitable in clinical practice. © 2022 The Author(s).eninfo:eu-repo/semantics/openAccessGuttaflow BiosealIroot SpPush-Out Bond StrengthRoot Canal ObturationArticle164N/AQ3229233