Elbey, Mehmet AliKalkan, Mehmet EminAkdag, SerkanOzbek, KeremEren, Nihan KahyaDemirtas, SinanYuksel, Murat2025-05-102025-05-1020131897-55931898-018X10.5603/CJ.2013.00792-s2.0-84885208591https://doi.org/10.5603/CJ.2013.0079https://hdl.handle.net/20.500.14720/16092Ozbek, Kerem/0000-0002-0603-3976; Yuksel, Murat/0000-0003-2636-5211Background: Our aim was to investigate the clinical and prognostic features of the patients with prosthetic valve endocarditis (PVE) in a multicenter nation-wide study. Methods: The present nation-wide study consisted of 75 consecutive patients with PVE treated at 13 major hospitals in Turkey from 2005 to 2012. Results: The patients who died during follow-up were significantly older than the survivors and had higher C-reactive protein (CRP), creatinine, poor NYHA functional class and large vegetations. High creatinine level (odds ratio [OR] 2.6, 95% confidence interval [CI] 1.14-6.13), poor functional status (OR 24.5; 95% CI 3.1-196.5) and high CRP (OR 1.02; 95% CI 1.00-1.03) measured on admission were independent risk associates for in-hospital mortality Conclusions: High creatinine level, poor functional status and high CRP measured on admission were independent risk associates for in-hospital mortality, whereas a NYHA class of III/IV and high CRP reflected independent risk for stroke/mortality end point.eninfo:eu-repo/semantics/openAccessInfective EndocarditisMortalityPrognostic FactorsArticle203Q3Q232332823788308WOS:000320776400016