Cinar, TufanSaylik, FaysalHayiroglu, Mert IlkerAsal, SuhaSelcuk, MuratCicek, VedatTanboga, Ibrahim Halil2025-05-102025-05-1020230003-31971940-157410.1177/00033197221110700https://doi.org/10.1177/00033197221110700https://hdl.handle.net/20.500.14720/14172Hayiroglu, Mert/0000-0001-6515-7349; Tanboga, Ibrahim Halil/0000-0003-4546-9227; Cinar, Tufan/0000-0001-8188-5020The goal of this investigation was to explore the relationship between serum uric acid/albumin ratio (UAR) and no-reflow (NR) in ST elevation myocardial infarction (STEMI) patients (n = 838) who underwent primary percutaneous coronary intervention (pPCI). Angiographic NR was defined as thrombolysis in myocardial infarction (TIMI) flows 0, 1, and 2 in the absence of coronary spasm or dissection. NR developed in 91 (10.9%) STEMI patients. Patients with NR had higher UAR and according to multivariable logistic regression models, a high UAR was an independent risk factor for NR. The area under the curve (AUC) value of the UAR was .760 (95%CI: .720-.801) in a receiver-operating characteristics curve (ROC) assessment. Notably, the UAR AUC value was greater than that of its components: albumin (AUC: .642) and serum uric acid (AUC: .637) (P < .05 for both comparisons). The optimum UAR value in detecting NR in STEMI patients was >1.21 with a sensitivity of 82% and a specificity of 67%. This was the first study to report that the UAR was independently associated with NR in STEMI patients who underwent pPCI.eninfo:eu-repo/semantics/closedAccessUric AcidAlbumin RatioNo-ReflowSt Elevation Myocardial InfarctionPrimary Percutaneous Coronary InterventionArticle744Q3Q238138635726733WOS:000814083400001