Guler, AyseSahin, H. GulerKucukaydin, ZehraErdemoglu, Evrim2025-05-102025-05-1020101309-03991309-038010.5152/jtgga.2010.332-s2.0-79251538965https://doi.org/10.5152/jtgga.2010.33https://search.trdizin.gov.tr/en/yayin/detay/115688/comparison-of-the-efficacy-of-intrauterine-lidocaine-paracervical-block-and-oral-etodolac-for-decreasing-pain-in-endometrial-biopsyhttps://hdl.handle.net/20.500.14720/20564Kucukaydin, Zehra/0000-0001-5908-2408; Erdemoglu, Evrim/0000-0002-5993-6968Objective: To compare the effectiveness of paracervical block, intrauterine lidocaine and oral etodolac in decreasing the pain caused by pipelle endometrial sampling. A secondary goal of this study was to determine the adverse effects and compare possible effects of these methods on pulse and blood pressure. Material and Methods: The study was performed between April 2006 and October 2006 in the Obstetrics and Gynecology Department of Van Yriziincji Yil University Research Hospital. One-hundred twenty patients were randomized into four groups: 1. Group: Paracervical block was performed with 3 ml 2% prilocaine solution. 2. Group: Five ml of 2% lidocaine solution was instilled through the endocervix into the uterine cavity. 3. Group: Subjects received 400 mg oral etodolac tablet 1-1.5 hour before the procedure. 4. Group: No method of anesthesia was used in the control group. Endometrial sampling was performed with pipelle. Severity of pain during the procedure was scored by the subjects according to the "6-point Verbal Rating Scale (VRS)". Blood pressure and pulse rate were measured before, during and 30 minutes after the procedure. Results: Pain scores in intrauterine lidocaine group (2"d group) were found statistically significantly lower than the other three groups (p<0.05). Conclusion: Intrauterine lidocaine anesthesia technique decreases pain in endometrial sampling with pipelle more efficiently than paracervical block or oral etodolac. While indication of menorrhagia and endometrial thickness more than 5 mm increased pain scores, intrauterine lidocaine application or paracervical block decreased tyre scores significantly (p<0.05).eninfo:eu-repo/semantics/openAccessAnesthesiaLidocainePainArticle114N/AQ317818124591932115688WOS:000420635500002