Cibuk, SalihMert, HandanMert, NihatTuncer, OguzAltindag, FikretKaraman, KamuranMeydan, Ismet2025-05-102025-05-1020231042-01501029-495310.1080/10420150.2022.21634892-s2.0-85145832168https://doi.org/10.1080/10420150.2022.2163489https://hdl.handle.net/20.500.14720/985Meydan, Ismet/0000-0001-5640-6665; Cibuk, Salih/0000-0001-5427-4929; Ozdek, Ugur/0000-0002-0709-1545In this study, the effect of early X-ray exposure on infertility was investigated by creating a newborn model with rats. Fifteen Pregnant rats were divided into five groups. After birth, the study was continued with 12 babies (6 males, 6 females) rat in each group. Different amounts of X-rays were applied to the experimental groups. At the end of the experiment, there was found that testosterone levels decreased in all experimental groups compared to the control group (P < 0.05). When the experimental groups were compared to the control group, there was a decrease in the number of spermatogoniums from all the experimental groups. The decrease in group II, group III and group IV was found to be statistically significant (P < 0.05). As a result, exposure to X-rays in new-borns and premature babies; It was observed that it caused disruption of caspase signaling in gonad organs, a serious decrease in hormonal activity, a significant decrease in spermatogonia number and a decrease in the number of primordial follicles. Considering these results, it can be predicted that exposure to X-rays in the neonatal period, especially in the premature period, may lead to infertility in later life.eninfo:eu-repo/semantics/closedAccessX-RayIonizing RadiationNewbornInfertilityRatEffects of X-Ray Application on Infertility in New-Born RatsArticle1785-6N/AQ3607619WOS:000908440700001