Browsing by Author "Çilli, A.S."

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Imipramine Treatment of Panic Disorder Patients With Frequent Sleep Panic
(1999) Aǧargün, M.Y.; Kara, H.; Çilli, A.S.
Objective: The aim of this study was to examine the effectiveness of imipramine treatment in the panic disorder patients who had frequent sleep panic attacks as predominant clinical features. Method: Thirteen patients whose sleep panic attacks represented their primary complaint at the time of admission were given imipramine for an 8-week trial. Results: 150 mg/day imipramine treatment reduced the frequency and the severity of sleep panic attacks in patients. Conclusions: These findings suggest that imipramine is useful in the treatment of this subgroup patients of panic disorder.
Psychopharmacological Treatment Response in Obsessive Compulsive Patients With Autogenous and Reactive Obsessions
(2007) Beşiroǧlu, L.; Uǧuz, F.; Saǧlam, M.; Aǧargün, M.Y.; Aşkin, R.; Çilli, A.S.
Objective: It has been suggested that obsessions related with different cognitive process can be discriminated as autogenous and reactive obsessions. This study aimed to compare treatment response to psychopharmacological interventions of the OCD patients with autogenous and reactive obsessions. Methods: Using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS) and White Bear Suppression Inventory we assessed 20 patients with auotogenous obsessions (Autogenous group, AG) and 22 patients with reactive obsessions (Reactive group, RG) who met the DSM-IV criteria for OCD. The patients were consecutively assigned to receive either sertraline (100-200 mg/day), fluvoxamine (200-300 mg/day) or paroxetine (40-80 mg/day). We reassessed 80% of the initial AG (n=16) and 68% of initial RG (n=15) after 12 weeks. Results: The YBOCS obsession, compulsion, total scores, HDRS and WBSI scores at follow-up in both AG and RG were significantly lower than at baseline scores. The mean differences from baseline to follow up for obsession severity and suppression tendency in the AG were significantly higher than RG. The relationships between mean differences from baseline to follow up assessments on severity of obsessions, depressive symptoms and suppression tendency were found to be significant in the AG. Mean difference from baseline to follow up assessments on severity of obsessions were significantly associated with mean difference for compulsion severity in the RG. Conclusions: Discrimination for obsessions based on autogenous versus reactive may have implications for identifying psychopathological mechanisms implicated in the OCD, and for understanding variability in treatment response.
Repetitive and Frightening Dreams and Suicidal Behavior in Patients With Major Depression
(W.B. Saunders, 1998) Aǧargün, M.Y.; Çilli, A.S.; Kara, H.; Tarhan, N.; Kincir, F.; Öz, H.
The purpose of the present study was to examine the association between repetitive and frightening dreams and suicidal tendency in patients with major depression. Depressed patients who reported frequent nightmare (N = 29) and depressed patients who reported dreaming but never nightmares (N = 34) were evaluated using the Schedule for Affective Disorders and Schizophrenia (SADS) suicide subscale to rate the severity of active suicidality. The patients with frequent nightmares, particularly women, had higher mean SADS suicide subscale scores and were more likely to be classified as suicidal than the others. The findings demonstrate that frequent nightmares are associated with suicidal tendency in patients with major depression. Theoretical and clinical implications for the function of dreaming are discussed.