Browsing by Author "Özbay, B"

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Bronchobiliary Fistula Due To Hydatid Disease of the Liver
(Acta Medical Belgica, 2002) Uzun, K; Özbay, B; Etlik, Ö; Kotan, Ç; Gencer, M; Sakarya, ME
As a complication of hydatid cyst disease of the liver, bronchobiliary fistula is a rare condition and manifests as bilioptysis. We report the case of a 34 year-old man with echinococcosis of the liver who developed a bronchobiliary fistula which manifested as chronic cough and bile stained sputum. A chest X-ray showed an unilateral infiltrate in the costodiaphragmatic angle. Bronchoscopy revealed bile filling the right basal bronchi. Magnetic resonance cystography revealed that the hepatic bile ducts communicated with the right basal pleural space. Percutaneous transhepatic drainage was applied. When the patient was reevaluated, the hydatid cyst had eroded into the pleural space, and a pleural effusion had developed. The condition of the patient deteriorated. Hence, surgical therapy was performed. After surgery, the condition of the patient improved. He was discharged from the hospital in good condition.
Distribution of Mast Cells in Lung Tissues of Rats Exposed To Biomass Smoke
(Scandinavian Federation Laboratory Animal Science, 2004) Kanter, M; Yörük, M; Özbay, B; Karaca, T; Acar, S; Coskun, O
This study was designed to evaluate the distribution of mast cells in the lung tissues of rats exposed to biomass smoke. Fifty six female Wistar albino adult rats were used. They were divided into two experimental groups (control and biomass smoke-treated), each containing 28 animals. Control rats were not exposed to the biomass smoke at any time during the experiment. Rats in the treatment group were exposed daily (one hour) to biomass smoke for 3, 6 or 9 months. Lung tissues samples were obtained under deep anesthesia from the randomly selected 7 animals in both groups. Lung tissues were fixed in Mota's fixative (BLA) for 24 h and embedded in paraffin. Sections of 6 put thickness were cut and stained with 0.5% toluidine blue in 0.5 N hydrochloric acid at pH 0.5 for 30 min. The numbers of mast cell in lung tissues of the animals exposed to the biomass for 6 or 9 months were significantly (P<0.05) higher than controls. This study showed that long term exposure to biomass smoke was associated with the increased number of mast cells in the lung.
Evaluation of Diaphragmatic Movement With Mr Fluoroscopy in Chronic Obstructive Pulmonary Disease
(Elsevier Science inc, 2000) Ünal, Ö; Arslan, H; Uzun, K; Özbay, B; Sakarya, ME
The aim of this study was to show reduction of the diaphragmatic excursion with MR fluoroscopy in patients with chronic obstructive pulmonary disease (COPD) and to compare the results with pulmonary function test (PFT). The study included 13 men and 10 women (average age 56.2) with COPD, and 9 men and 6 women (average age 55.8) as a control group. MR fluoroscopy images with Spoiled Gradient-echo pulse sequence was obtained during deep inspiration and expiration. After examination, over cine-loop display, the highest and lowest positions of the diaphragm were identified and the distance of excursion was measured. Differences in the diaphragmatic excursion between patient and healthy subjects were compared. We have also compared MR fluoroscopy results with PFT. In each person of both groups, excursion of the diaphragm was demonstrated clearly in cine-loop display. Differences of excursion between deepest and highest point of diaphragm were on average 26 and 20 mm, respectively, in the right and left side in patients and 69 and 56 mm in healthy group. Significant correlation was found between expiratory volume in 1 s and MR fluoroscopy results. MR fluoroscopy study showed that there were significant statistical differences in diaphragmatic excursion between patients with COPD and healthy subjects. Expiratory volume in 1 s is closely associated with the diaphragmatic excursion. MR fluoroscopy would seem to be a useful method for showing diaphragmatic excursion. (C) 2001 Elsevier Science Inc. All rights reserved.
Extrahepatic Biliary Obstruction Caused by Small-Cell Lung Cancer
(Taylor & Francis Ltd, 2001) Kotan, C; Er, M; Özbay, B; Uzun, K; Barut, I; Ozgoren, E
The pancreas is a rare site of metastasis from small-cell lung cancer (SCLC). We present the case of a pancreatic metastasis of small-cell lung, cancer associated with jaundice, in which, initially, the case was evaluated as a primary pancreatic carcinoma and pancreaticoduodenectomy was performed. We also review the reported cases of pancreatic metastases from SCLC.
Extrapulmonary Tuberculosis in High Prevalence of Tuberculosis and Low Prevalence of Hiv
(W B Saunders Co, 2002) Özbay, B; Uzun, K
The aim of this study was to analyze some clinical and epidemiologic aspects of extrapulmonary tuberculosis (EPTB) diagnosed at the university hospital, and to investigate HIV seropositivity among the patients with extrapulmonary tuberculosis. In this study, the most frequent sites of extrapulmonary tuberculosis were the pleura, meninx, and lymph nodes. Pleural involvement was most common among the young and military servicing males. The authors results show that HIV infection is an unlikely factor in the etiology of extrapulmonary tuberculosis in the authors' region, for the present.
Frequency of Sinusitis in the Patients With Pneumonia
(Elsevier Science inc, 2002) Özbay, B; Arslan, H
The aim of this study was to investigate the frequency of sinusitis in patients with pneumonia. Among 50 Consecutive patients with pneumonia, 19 cases, which had Waters' roentgenograms in their Cites. were retrospectively reviewed in relation with sinusitis. Sixteen of them had sinusitis signs in their roentgenograms. The sinusitis frequency was 84% in patients with pneumonia who had paranasal sinus roentgenograms. These findings suggest that sinusitis may be an important causative factor for pneumonia and that it Should be considered when evaluating a patient with pneumonia. (C) 2002 Elsevier Science Inc. All rights reserved.
Lipid Peroxidation and Antioxidant Enzymes in Turkish Population
(Tohoku Univ Medical Press, 2002) Özbay, B; Dülger, H
OZBAY, B. and DULGER, H. Lipid Peroxidation and Antioxidant Enzymes in Turkish Population: Relation to Age, Gender, Exercise, and Smoking. Tohoku J. Exp. Med., 2002, 197 (2), 119-124 - The purpose of this study was to examine the change in lipid peroxidation and antioxidant enzyme activities in healthy subjects and to evaluate the concentrations of superoxide dismutase, glutathione peroxidase and malondialdehyde, an end product of lipid peroxidation in exercise and smoking. Study included 257 appearently healthy individuals, 133 males and 124 females. In all subjects, malondialdehyde (MDA) levels were analyzed as an indicator of the lipid peroxidation activities. Superoxide dismutase, glutathione peroxidase activities were measured as an indicator of antioxidant activities. Oxidative stress was estimated by the method based on thiobarbituric acid reactivity. Erythrocyte superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were estimated on hemolysates by use of commercial available kits (Randox lab., Dublin, Ireland). For all groups serum lipid peroxidation and erythrocyte SOD and GSH-Px were obtained at the initial and the following periods. Serum MDA level was higher in the elderly than in the children and in the adults. MDA levels were higher in the smoking, acute exercise than their counterparts in the control groups. GSH-Px activity was significantly lower in the acute exercise group, and higher in the trained group than those as controls. SOD decreased in the elderly, smoking and acute exercise groups and increased in trained individuals. There was a significant increase in lipid peroxidation activity and a significant decrease in antioxidant enzyme activity in cases of acute exercise and smoking as well as the elderly - lipid peroxidation; antioxidants; smoking; exercise. (C) 2002 Tohoku University Medical Press.
Relapsing Polychondritis
(Karger, 1998) Özbay, B; Dilek, FH; Yalçinkaya, I; Gencer, M
In this article, we report on a 40-year-old man with relapsing polychondritis (RP) of the tracheobronchial tree without clinical manifestations of other systems including nasal septum and earlobe cartilage involvement. The illness was diagnosed histologically, and treatment with procaine penicillin was successful. RP is an unusual systemic disorder characterized by widespread inflammation and destruction of cartilage tissues. The main cause is usually autoimmune. In RP various clinical manifestations including nasal chondritis, arthritis, scleritis, damage to tracheal and bronchial cartilage, and aortic, cardiac, and renal involvement may occur. Isolated tracheobronchial involve ment is very rare. The diagnosis must be based on a combination of clinical and pathologic features. If diagnosed early, appropriate treatment may prevent life-threatening airway obstruction.
Surgical Treatment of Hydatid Cyst of the Lung
(Munksgaard int Publ Ltd, 1999) Yalçinkaya, I; Er, M; Özbay, B; Ugras, S
Hydatid cyst disease is still a problem in Turkey, especially in the east Anatolian region, as well as in many other places in the world. A retrospective review was made of the surgical treatment of 30 patients with pulmonary hydatid cysts during the last 3 yrs. Nineteen patients were male and 11 female with an average age of 23.5 yrs (range 4-44 yrs). Cystotomy and capitonnage mere performed in 28 of the 30 cases (93.4%), The transdiaphragmatic route or simultaneous laparotomy mas preferred when the liver was involved. Albendazole was used in four patients with multiple hydatid cyst due to probable recurrence in the postoperative period. Cough and chest pain were the prominent symptoms in the majority of cases. A single lobe was affected in 22 patients, Unilateral multiple foci were present in four patients and bilateral multiple foci in four. Six patients had concomitant liver cysts. Morbidity was low and no mortality was seen. No recurrences were seen on control chest radiographs during the last 2-yr follow-up. In the treatment of hydatid cyst of the lung, conservative surgical methods such as cystotomy and capitonnage still remain the treatment of choice. Medical treatment could be used for prophylactic purposes and in some instances, but the percutaneous aspiration method should not be performed.