Browsing by Author "Özgökçe, M."

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A Case of Lung Adenocarcinoma Presenting as Miliary Appearance
(Yuzuncu Yil Universitesi Tip Fakultesi, 2020) Çilingir, B.M.; Sunnetcioglu, A.; Özgökçe, M.; Bayram, I.
Multiple benign conditions may be the cause of miliary nodules, but the most common cause is metastatic disease. Even so miliary metastasis of lung cancer is rarely seen. The most common lung cancer with a miliary distribution is adenocarcinoma. It is often difficult to diagnose adenocarcinomas with a progressive course. Anamnesis, physical examination, imaging methods can give an idea but diagnosis should be confirmed histopathologically. As in our case, tissue biopsy should be performed for diagnosis. We aimed to present this case because we performed a tru cut biopsy which is rarely used for histopathologic diagnosis and the miliary nodules in the lung of adenocarcinoma is a rare condition. © 2020, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
The Comparison of Diffusion Weighted Imaging (Dwi) With Other Breast Mri Parameters in the Diagnosis of Breast Masses
(Yuzuncu Yil Universitesi Tip Fakultesi, 2019) Özgökçe, M.; Havan, N.; Cuce, F.; Durmaz, F.; Sakci, Z.
The breast MRI parameters such as morphologic features, enhancement kinetics and diffusion restriction can be used for the differential diagnosis. We aimed to compare the Apperant Diffusion Coefficient (ADC) values of masses with other MRI parameters in diagnosis of breast masses. Between March 2014 and September 2017, 49 female patients in whom a breast mass was diagnosed, determined using ultrasound and mammography and who were further examined with MRI, were enrolled to this study. Total 51 lesions were detected. Routine breast MRI protocol was performed and images were evaluated. The ADC cut-off value was taken as 1,1×10-3mm2 /s according to the literature. Fifty-one lesions were diagnosed with biopsy. Of these lesions, 23 (45.1%) were malignant (20 invasive ductal carcinoma and others) and 28 (54.9%) were benign (20 fibroadenomas and others). The accuracy rate of DCE assessment of MRI was 90,9% for benign lesions in with a type 1 curved lesions, and 81,8% for malign lesions in with a type 3 curved lesions. The accuracy rate of ADC values was 93,1% for benign lesions and 95,5% for malign lesions. We believe that the ADC value can provide a higher diagnostic accuracy with the combination of morphological characteristics and contrast kinetics of the lesion and that ADC can be used alone because of its high diagnostic accuracy in some cases. © 2019, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Computed Tomography Findings of Atypical Intralobar Pulmonary Sequestration: a Case Series
(Tabriz University of Medical Sciences, 2021) Özkaçmaz, S.; Özgökçe, M.; Akıncı, M.B.; Durmaz, F.; Dündar, İ.; Göya, C.; Sayır, F.
Introduction: Bronchopulmonary sequestration is a rare congenital abnormality of the lung that has two different types as intralobar and extralobar. In this study, we aimed to present six cases of intralobar sequestration with atypical findings in terms of feeding, drainage, and localization. Methods: Patients diagnosed with intralobar pulmonary sequestration in our clinic between 2015 and 2019 were evaluated retrospectively. Demographical features and atypical computed tomography (CT) findings of the patients were presented by literature. Results: Among 45 patients with intralobar sequestration, 6 (13.3%) (5 males and 1 female) with a mean age of 43.5±25.4(0-78) years old had atypical pulmonary findings on CT images. Atypical features regarding arterial supply was detected in 8.9%, venous drainage in 2.2%, location in 4.4%, radiological appearance in 4.4% and co-existing lesion in 2.2% of the patient with intralobar sequestration. Conclusion: Typical and atypical features of pulmonary sequestration must be well-known for differential diagnosis of solid or cystic pulmonary lesions. © 2021 The Author(s).
Contribution of Sonoelastography in the Differentiation of Benign and Malignant Breast Masses: a Comparative Analysis on Sonographic Birads Classification
(Yuzuncu Yil Universitesi Tip Fakultesi, 2017) Arslan, H.; Akdemir, Z.; Yavuz, A.; İslamoglu, N.; Çelik, S.; Özgökçe, M.; Tolunay, H.E.
In this study, we aimed to investigate the effectivity of ultrasonographic elastography in the differentiation of benign and malignant lesions detected on B-mode ultrasonography. The retrospective study included 133 consecutive patients who underwent B-mode USG followed by elastography between January 2013 and December 2015. The lesions were scored by using B-mode USG with breast imaging-report and data systems (BIRADS) and then sonoelastographic color-coded maps were obtained by elastography in a single session. Sonoelastographic scoring was achieved with a 5-point scoring system. Elasticity scores and strain ratio (SR) values were compared with histopathological findings. The 133 patients included 132 (99.2%) women and 1 (0.8%) man. Mean age was 40.45±14.8 years. The lesions were mostly localized in the left breast (n=70, 52.3% vs. n=63, 47.7%). Depending on the pathological findings, 94 (71.2%) lesions were classified as benign and 39 (28.8%) as malignant. Mean SR value was 4.419±1.43, with 5.5 in malignant lesions and 4.3 in benign lesions. At the cut-off value of 4.95 for SR, the sensitivity and specificity of USG in elastographic examination were 81.6% and 78.7%, respectively. A significant correlation was found between the SR value and the BIRADS score calculated on USG (rho=0.86; two-tailed; p<0.001). Similarly, a significant correlation was found between the SR value and the elasticity score (rho=0.88; two-tailed; p<0.001). In conclusion, the use of sonoelastographic examination following the USG examination with B-mode ultrasonography can be a complementary diagnostic method that increases the specificity of USG. Moreover, it can also reduce unnecessary biopsies in lesions with suspicious malignancy. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Gastric Duplication Cyst: a Rare Case Report
(Logos Medical Publishing, 2021) Avcı, V.; Çelik, R.; Özgökçe, M.
Duplication cysts are developmental anomalies of gastrointestinal tract that can occur at any level from the oral cavity to the rectum, and are extremely rare in the stomach. Most patients show symptom and findings in the first year of life. The most common symptom and findings are abdominal pain, nausea, vomiting, anemia, weight loss and palpable mass. In this study, a gastric duplication cyst was presented in an 11-month-old patient. © Copyright Turkey Association of Pediatric Surgery. This journal published by Logos Medical Publishing.
Radiological Appearance of Hiatal Hernias on Computed Tomography
(Yuzuncu Yil Universitesi Tip Fakultesi, 2022) Ayyildiz, V.A.; Özgökçe, M.; Türkoğlu, S.; Dündar, I.; Durmaz, F.; Özkaçmaz, S.; Türko, E.
A hiatal hernia is the herniation of organs and structures in the abdominal cavity through the esophageal opening of the diaphragm. We aimed to present the tomographic findings of hiatal hernia types. The computed tomography (CT) images and demographic characteristics of the patients diagnosed with hiatal hernias based on contrast-enhanced and/or non-contrast thorax-abdominal CT scan between January 2016 and December 2019 were retrospectively reviewed (Material & Method shortened in abstract.). Oral contrast material wasn’t given to the patients. (Added) 210 patients with hiatal hernias, 126 (60%) were female and 84 (40%) were male. Among these patients, 124 (59 %) had type 1, 76 (36 %) had type 2, nine (4.2 %) had type 3, and one (0.4 %) had type 4 hiatal hernia. The most common complaints were cough (64%) and mild shortness of breath (34%). The most common clinical signs seen in the majority of patients were weight loss (73%) and loss of appetite (41%). All of the cases were mainly diagnosed based on radiological (CT) findings. With the increase in the use of CT for thoracic and abdominal diseases, there has been an increase in the frequency of incidental detection of hiatal hernias. Hernia diagnosis is important for preoperative surgical planning. Radiologists should be aware that complications of hiatal hernia can cause morbidity and mortality. The best diagnosis method is considered as CT, which is also useful in determining the type of hiatal hernias. © 2022, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Radiological Tips on Safe Tract Selection in Computed Tomography-Guided Transthoracic Biopsy: Single-Center Results
(Tabriz University of Medical Sciences, 2024) Koca, H.; Özgökçe, M.; Akinci, M.B.; Durmaz, F.; Ayyildiz, V.A.; Özkaçmaz, S.; Göya, C.
Introduction: The vast majority of lung masses are malignant. Benign lung masses include granulomatous inflammation and pneumonia consolidations. Malignant lung masses include lung cancers, lymphoma, and thymic neoplasms. Differentiating benign-malignant lung masses and treatment planning are essential for the prognosis of patients. Computed tomography (CT) guided transthoracic lung biopsy is a reliable diagnostic method with high accuracy and relatively few complications when an appropriate trace is selected. In this study, we aimed to present our experience and the results of lung mass cases that we biopsied with the guidance of CT. Methods: A total of 57 patients who were referred to us for clinicoradiological transthoracic biopsy (TTB) were studied with CT-guided histopathological sampling. The study did not include patients with no pathology results and ultrasound-guided biopsy. Results: A total of 57 patients, 42 male (73.6%) and 15 female (26.4%) with a mean age of 59.05 ± 17.04 (1-85), were evaluated. Thirteen of the lesions were reported as benign (22.8%), and 44 as malignant (77.2%). Conclusion: When an appropriate trace is selected, CT-guided transthoracic lung biopsy is a reliable diagnostic method with high accuracy and relatively few complications. © 2024 The Author(s).
Renal Artery Embolism on the Contralateral Kidney After a Radical Nephrectomy
(Logos Medical Publishing, 2018) Gül, A.; Yentür, S.; Özgökçe, M.
Renal artery occlusion results commonly from thromboembolism to renal artery from distant vascular system. Hyperhomocysteinemia is one of the hereditary hypercoagulability reasons. In order to elicit ethiology in the cases of arterial thrombosis, necessity of hypercoagulopathy screening tests is still controversial. Diagnosis of renal artery thromboembolism should be remembered in the patients who develop postoperative anuria and renal angiographic intervention must be performed immediately for thrombolytic therapy after renovascular imaging. We report a case of a 54-year-old woman with renal artery embolism on the contralateral kidney due to hyperhomocysteinemia after an open left radical nephrectomy. © 2018, Logos Medical Publishing. All rights reserved.
Retroperitoneal Abscesses: Origin, Ethiology and Percutaneous Treatment
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Aslan, R.; Özgökçe, M.; Eryılmaz, R.; Duran, M.A.; Yıldızhan, M.; Taken, K.
Retroperitoneal abscess is a rare clinical condition that can cause mortality if not properly treated. In our study, we aimed to report the data of retroperitoneal abscess cases which performed percutaneous drainage in the first step treatment. A retrospective study was made of 81 patients with retroperitoneal abscesses treated at our hospital from June 2010 to December 2017 for the purpose of analyzing the diagnosis and treatment of these rare infections. In each case, we analyzed patient characteristics, abscess location and origin, predisposing factors, c linical presentation, microbiology, radiographic findings, treatment, and outcome. 81 cases were identified as 11 (14%) primary and 70 (86%) as secondary. The majority (63%) of these abscesses were originated from Urinary System, while others were found to be originated from psoas, vertebral and Gastrointestinal system (GIS). Urolithiasis, previous surgery, and other Urinary system anomalies were determined to be the most common predisposing factors. Escherichia coli (E. coli) was the most commonly seen pathogen in abscess culture. In all patients, percutaneous drainage catheter was successfully placed in the abscess lodge. No serious complications occurred in patients during and after the procedure. 78/81 (96%) clinical success was achieved. In 12 months fo llow-ups, recurrence was seen in only 5 patients. Percutaneous abscess drainage should be preferred in the treatment of retroperitoneal abscesses as easy to perform, cost effective, low complication risk and high success rate. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Scott-Taor Syndrome
(Elsevier Masson SAS, 2017) Ayyıldız, V.A.; Özgökçe, M.; Oğul, H.
Sleep Apnea and Fatty Liver Are Coupled Via Energy Metabolism
(International Scientific Literature Inc., 2016) Arısoy, A.; Sertoğullarından, B.; Ekin, S.; Özgökçe, M.; Bulut, M.D.; Huyut, M.T.; Turan, M.
Background: Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by intermittent hypoxia. Non-alcoholic fatty liver disease is the most common cause of chronic liver disease worldwide. We aimed to evaluate the relationship between OSA and fatty liver. Material/Methods: We enrolled 176 subjects to this study who underwent polysomnography (PSG) for suspected OSA. The control group included 42 simple snoring subjects. PSG, biochemical tests, and ultrasonographic examination were performed all subjects. Results: The simple snoring and mild, moderate, and severe OSA groups included 18/42 (42.86%), 33/52 (63.5%), 27/34 (79.4%), and 28/48 (79.2%) subjects with hepatosteatosis, respectively. There were significant differences in hepatosteatosis and hepatosteatosis grade between the simple snoring and the moderate and severe OSA groups. Logistic regression analysis showed that BMI and average desaturation were independently and significantly related to hepatic steatosis. Conclusions: Our study shows that BMI and the average desaturation contribute to non-alcoholic fatty liver in subjects with OSA. In this regard, sleep apnea may trigger metabolic mitochondrial energy associated processes thereby altering lipid metabolism and obesity as well. © Med Sci Monit, 2016.
A Tumor-Mimicking Parasitic Disease: Radiological Findings of Alveolar Echinococcosis
(Tabriz University of Medical Sciences, 2021) Türkoğlu, S.; Özgökçe, M.
Introduction: Alveolar echinococcosis (AE) is a tumor-mimicking parasitic disease caused by Echinococcus multilocularis. In this study, we aimed to present the radiological imaging findings of AE characterized by malignant features. Methods: The radiological findings of 20 patients who were admitted to our hospital in Van province between years 2014 and 2020 and were diagnosed with AE were retrospectively evaluated. Of these patients, 30% had been operated due to a preliminary diagnosis of a tumor. The study was conducted retrospectively by examining the drawback radiological images of patients from the radiological data archiving system. The diagnosis of AE was confirmed when lesions manifested the following radiological imaging findings: irregular margins, no contrast uptake in dynamic contrast images or late peripheral enhancement, presence of calcifications, and contralateral lobe hypertrophy. Results: The mean age of the patients at the time of diagnosis was 50.95 (12-86) years. Of the patients, 15 (75%) were women and 5 (25%) were men. Typical histopathological and radiological imaging findings were present in 8 (40%) and 17 (85%) patients, respectively. Only 12 (60%) out of 20 patients had seropositivity by ELISA. The remaining 8 (40%) patients were seronegative. Conclusion: Radiological imaging examinations are essential in diagnosis and evaluation of the extent of the disease. Different radiological techniques can be used to differentiate AE from other diseases. Early diagnosis is important for avoiding unnecessary or inadequate operations due to a misdiagnosis and preventing potential complications. © 2021 The Author(s).