Browsing by Author "Agaoglu, Z"

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Concentration of Zn, Cu, Mn and Mg in Cattle With Natural Psoroptes Bovis Scabiei
(indian veterinary Journal, 2005) Kozat, S; Ekin, S; Yuksek, N; Kaya, A; Agaoglu, Z
Scabies is caused by Psoroptes bovis. The most cited causes of the disease are the over crowded accommodation of the animals in the barns, malnutrition and imbalanced feeding (Sargison et al., 1995; Sekin et al., 1998). Trace elements and minerals are of a prominent value in terms of increasing the resistance against the disease in the biological organisms, causing severe clinical conditions. in case of their shortage or excess (Underwood and Suttle, 2001). The aim of this study is to find out the levels of zinc (Zn), copper (Cu) Manganese (Mn) and Magnesium (Mg) in Psoroptes scabiei in cattle.
The Effects of Succinlycholine on Some Clinical, Haematological and Biochemical Parameters in Dogs
(indian veterinary Journal, 2004) Akkan, HA; Genccelep, M; Karaca, M; Ceylan, E; Tutuncu, M; Agaoglu, Z; Aytekin, I
Due to increasing population of street dogs the health and life style of human beings are affected. Some methods require chemicals to capture and regulate the stray animals. Succinylcholine is a short-acting depolarising, neuromuscular blocking agent used for capturing animals (Hicks and Bailey, 1978) in the present study the effects of succinyl choline in street dogs have been evaluated.
Erythropoietin Level and Some Blood Parameters in Cattle With Tropical Theileriosis
(indian veterinary Journal, 2004) Ceylan, E; Agaoglu, Z; Gul, Y; Meral, I; Dabak, M
Haemobartonellosis in Van Cats
(Tubitak Scientific & Technological Research Council Turkey, 2005) Akkan, HA; Karaca, M; Tütüncü, M; Özdal, N; Yüksek, N; Agaoglu, Z; Deger, S
The present study was conducted to determine prevalence of Haemobartonella felis in Van cats. 121 Van cats (82 female, 39 male, aged 1-9 years) were the materials of the study, To determine biochemical and haematological parameters, 2 ml blood with and without anticoagulant were taken according to technique from vena cephalica antebrachii. H. felis was detected in blood smears preparations of 18 (14:88%) by Papenheim staining. Among biochemical parameters aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase (ALP), creatine phosphokinase (CPK) and bilirubin were in normal range as well as the packed cell volume (PCV) and red blood cell (RBC) counts. The infected cats were treated with oxytetracycline at 10 mg/kg dose intramuscularly (Geosol((R)) flacon, Vetas) or oral oxytetracycline at 10 mg/kg dose (Neoterramycine((R)) pow. Pfizer) for 15 days. After either above treatment blood smear preparations revealed negative for the rickettsia. In conclusion, potentially lethal infection of Haemobartonelia felis is prevalent in Van cats and can successfully be cured by oral or parenteral oxytetracycline application.
Light and Electron Microscopic Studies on Alpha Naphthyl Acetate Esterase Activity of the Peripheral Blood T Lymphocytes in Van Cats
(Wiley, 1998) Yoruk, M; Asti, RN; Kurtdede, N; Agaoglu, Z; Altunay, H
The purpose of this study was to determine the percentage of peripheral blood T Iymphocytes and the localization of ANAE enzyme at the electron microscopic level in Van cats by using an alpha-naphtyl acetate esterase procedure. Peripheral blood samples taken from 20 Van cats were used. The percentage of ANAE positive lymphocytes was 83.0%. Neutrophilic granulocytes gave a negative reaction, whereas monocytes, eosinophilic granulocytes showed a diffuse granular positivity. In the electron microscopic examination, ANAE positive reactions were seen in lysosomal granules found in lymphocytes.
Localization of Glycogen in the Placenta and Fetal and Maternal Livers of Cadmium-Exposed Diabetic Pregnant Rats
(Humana Press inc, 2003) Yoruk, M; Kanter, M; Meral, I; Agaoglu, Z
This study was designed to investigate the effects of Cd exposure on the glycogen localization in the placenta and in fetal and maternal livers in streptozotocin (STZ)-induced-diabetic pregnant rats. Ninety-nine virgin female Wistar rats (200-220 g) were mated with 33 males for at least 12 h. From the onset of pregnancy, the rats were divided into four experimental groups (control, Cd treated, STZ treated, and Cd+STZ treated). The Cd-treated group was injected subcutaneously daily with CdCl2 dissolved in isotonic NaCl, starting at the onset of pregnancy throughout the experiment. Diabetes was induced on d 13 of pregnancy by a single intraperitoneal injection of STZ in the STZ-treated group. In addition to the daily injection of Cd, a single intraperitoneal injection of STZ was also given on d 13 of pregnancy in the Cd+STZ-treated group. The rats received the last injection 24 h before being sacrificed and 10 randomly selected rats in each group were sacrificed on d 15 and d 20 of pregnancy. Blood samples were taken for determination of the serum glucose and insulin levels. Fetal and maternal livers of sacrificed rats in all groups were harvested on d 15 and d 20 of pregnancy, whereas placentas were harvested only on d 20 of pregnancy for histochemical examination. Although both Cd and STZ caused hyperglycemia and decreased insulin secretion, Cd-alone treatment increased the glycogen content only in the placental labyrinth, whereas STZ-alone treatment increased the glycogen content only in the maternal part of the placenta. Increased glycogen localization was observed in both the placental labyrinth and the maternal part of placenta when Cd and STZ were given together. Fetal and maternal livers of control and other treatment groups were not different regarding the glycogen content on d 15 or d 20 of pregnancy. It was concluded that Cd exposure during pregnancy might produce a glycogen localization in the placenta of diabetic rats. However, the function and the mechanisms of increased glycogen contents in the placenta of Cd-exposed pregnant diabetic rats remain unclear and further studies are needed.
Nephrotoxic Effect of Amphotericin B Administered in Different Doses and Infusion Mode in Dogs
(Vysoka Skola veterinarni Farmaceuticka, 2003) Ceylan, E; Akkan, HA; Tutuncu, M; Agaoglu, Z
In this study, nephrotoxic effect of Amphotericin B (AmB) was investigated together with clinical, biochemical, and histopathological findings in dogs intoxicated with different doses and methods of administration. 18 healthy cross-bred dogs were allocated to three groups. Amphotericin B diluted with sterile water was used. Dogs in group A (n = 6) were treated with 0.5 mg/kg AmB in 25 ml 5% dextrose as a rapid bolus (4-5 min). Dogs in group B (n = 6) were treated with 1 mg/kg AmB in 50 ml 5% dextrose as a rapid bolus (4-5 min). Dogs in group C (n = 6) were treated with 2 mg/kg AmB in 1000 ml 5% dextrose as a slow infusion (4-5 h). Clinical, haematological and biochemical analyses were made in all dogs before the experiment as well as on the 5(th) and 12(th) days. Haematological and biochemical values recorded before the experiment were compared with those on the 5(th) and 12(th) day. After the third day of the experiment, vomiting, diarrhoea, anorexia, fever, phlebitis, irritability and tachycardia were recorded in all dogs (Groups A, B and C). However, the symptoms recognised were minimum in Group C, moderate in Group A and severe in Group B. There were differences in biochemical values among groups (p < 0.001). Group B was different from Group A and C in haematological parameters (p < 0.05). The most severe histopathologic changes were observed in Group B animals. These results suggest that the toxicity of AmB on kidney could be decreased when it is administered in a long period and more diluted form.
Prevalence of Toxoplasmosis in Van Cats in Turkey
(indian veterinary Journal, 2003) Tutuncu, M; Akkan, HA; Karaca, M; Agaoglu, Z; Berktas, M
The Role of Antioxidant Vitamins (C and E), Selenium and Nigella Sativa in the Prevention of Liver Fibrosis and Cirrhosis in Rabbits
(M H Schaper Gmbh Co Kg, 2001) Türkdogan, MK; Agaoglu, Z; Yener, Z; Sekeroglu, R; Akkan, HA; Avci, ME
This experiment was carried out to investigate the role of antioxidants such as vitamin C and E, selenium and Nigella sativa (NS) on the prevention of carbon tetrachloride (CCl4)-induced liver fibrosis in rabbits. It was found that superoxide dismutase (SOD) values in ail of the treated groups were significantly lower than those of the control at 12(th) week of experiment (p < 0.05), while at 6(th) week and 12(th) week of experiment glutathione peroxidase (GSH-Px) values in the vitamin C treated group were significantly different from the control (p < 0.05). Histopathologically, hepatocellular necrosis, degeneration and advanced fibrosis were found in the control group. Lesions were minor and only confined to midzonal regions without centrilobular necrosis and fibrosis in the NS treated animals (group B). The lesions observed in the vitamin C treated animals (group C) were similar to that of the control group. Parenchymal changes with fibrosis were less in selenium and vitamin E treated animals (group D) than in those of the control group, but more obvious than in NS group. Histopathological findings demonstrate that NS might, at least partly, be successful in the prevention of liver fibrosis in rabbits. Vitamin E plus selenium had little therapeutic effect and vitamin C seemed to be ineffective, as far as the results of this study are concerned.
Serologic and Microscopic Studies on Babesiosis in Horses in the Eastern Border of Turkey
(William E Jones Dvm, 2003) Akkan, HA; Karaca, M; Tutuncu, M; Deger, S; Keles, I; Agaoglu, Z
Seronegativity of Equine Infectious Anemia in the East Border of Turkey
(indian veterinary Journal, 2004) Tutuncu, M; Akkan, HA; Karaca, M; Ceylan, E; Berktas, M; Agaoglu, Z
Equine infectious anemia (EIA), colloquially known as swamp fever, mountain fever, slow fever, equine malarial fever and Coggins disease, is a viral disease infecting all members of the Equidae including, horses, ponies, mules, and donkeys. (Sellon, 1993; Nakajima and Sugiura, 1994; Burki et al., 1992). Transmission of the virus requires direct blood transfusion, either by biting insects or other mechanical vectors such as contaminated needles. EIA usually is clinically diagnosed as a chronic disease with a high percentage of affected horses demonstrating weight loss, depression, dependent edema, and reduced haematocrit values, platelet counts, and haemoglobin. The majority of horses infected with EIA virus, however, appear to demonstrate none of the clinical abnormalities (Sellon, loc. cit.; Issel and Foil, 1984; Coggins, 1984). Turkey has a large horse population and, these horses are used for working, racing and breeding. The aim of this study was first to determine whether or not EIA is present in the east border of Turkey. There is no study on EIA in this region at present.
Seroprevalence of Listeria Monocytogenes Infection in Cattle in Van, Turkey
(indian veterinary Journal, 2005) Tutuncu, M; Solmaz, H; Akkan, HA; Karaca, M; Agaoglu, Z
Listeria monocytogenes, the most common pathogenic species of the genus Listeria, causes listeriosis in both people and animals manifested by encephalitis, abortion and septicaemia. The main route of transmission of L. monocytogenes is by ingestion of contaminated food and the disease is particularly common in ruminants fed on silage (Unnerstad et al, 2000; Low and Donachie, 1997). The aim of this study was to determine seroprevelance of L. monocytogenes infection in cattle of the region Van, Turkey using LLO as antigen.
Stomach Impaction in Ostriches (Struthio Camelus)
(Amer Assoc Avian Pathologists, 2002) Yüksek, N; Agaoglu, Z; Kaya, A; Aslan, L; Erdogan, HM; Akgul, Y
This study involved 14 ostriches of both sexes between 3 and 24 mo of age. Some hematologic and biochemical parameters were studied in animals with stomach impaction. Clinical examination of the birds revealed anorexia, emaciation, decreased defecation, listlessness, separation from the flock, and recumbence. The total number of leukocytes (10.4 x 10(3) mm(3)), the concentrations of serum glucose (166 mg/dl), and total protein (2.4 g/dl) decreased; serum creatine phosphokinase (1240 U/L) and alkaline phosphatase (598 U/L) increased; whereas no changes were found in the concentrations of calcium, phosphorus, magnesium, zinc, and copper. Medical treatment was initiated in 13 animals; six of them recovered and seven birds died. Necropsy revealed edema, erosions, and hemorrhagic ulcers in the stomach of the dead birds. Foreign bodies such as sand; stone; pieces of wood, glass, and plastic; and metallic objects were encountered in the stomach at the necropsy. In one bird, metallic foreign body was diagnosed and the bird was referred to surgery. Under stress factors, ostriches tend to eat foreign material; therefore, adequate housing, nutrition, and care are crucial in prevention of stomach impaction.
Studies on Some Haematological and Biochemical Parameters in Clinically Healthy Ostriches
(Tubitak Scientific & Technological Research Council Turkey, 2003) Agaoglu, Z; Yoksek, N; Altug, N; Kaya, A; Baydas, B
This study was carried out to determine the normal haematological and biochemical parameters of clinically healthy ostriches 1-3 years old of either sex. Red blood cells, white blood cells, haematocrit and haemoglobin values (as haematological parameters) and glucose, total protein, albumin, globulin, urea, kreatinine, serum enzymes (ALP, AST, ALT, GGT, CK, amilase) (as biochemical parameters) and electrolytes (Ca, P, Mg, Zn, Cu, Na, K, Cl) levels were measured. It was concluded that the values obtained in this study could be used as reference values for ostriches.
Zygomycotic Proventriculitis and Ventriculitis in Ostriches (Struthio Camelus) With Impaction
(Australian veterinary Assn, 2000) Gulbahar, MY; Agaoglu, Z; Biyik, H; Yuksek, N
Three young ostriches (Struthio camelus), aged 4 months, were found to have zygomycotic proventriculitis and ventriculitis associated with impaction. Clinical signs were anorexia, chronic weight loss, weakness and lethargy followed by scant faeces for seven days. Proventriculi and ventriculi from birds were full of masses of hay, grass, leaves and other fibrous materials in combination with sand, gravel and plastic. Erosions and haemorrhagic ulcers of varying number and severity were present in the mucosae of both organs involved. Mucosal lesions were characterized by haemorrhagic necrosis. Throughout the affected mucosae there were 5 to 12 mu-m wide rarely-septated fungal hyphae with non-parallel walls, irregular branching and occasional globoid distentions, typical of Zygomycetes. Zygomycotic proventriculitis and ventriculitis secondary to impaction was diagnosed.