Browsing by Author "Agaoglu, Z. T."

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Adenosine Deaminase in the Diagnosis of White Muscle Diseases in Lambs
(Polish Soc veterinary Sciences Editorial office, 2006) Altug, N.; Agaoglu, Z. T.; Yuksek, N.; Kaya, A.; Keles, I.
The aim of the study was to investigate the importance of ADA serum and its isoenzyme activity in diagnosing white muscle disease in lambs. The animal material used in the study was forty seven Akkaraman lambs - twenty seven of which had clinical signs of white muscle disease (white muscle disease group) and twenty healthy lambs (control group). Blood samples were taken and Se levels, CK, LDH, AST, ADA and ADA izoenzyme activity were determined. Following this, the animals in the white muscle disease group received I mg sodium selenit + 60 mg vitamin E intramuscularly as a single dose. Fourteen days following sodyum selenit + vitamin E application blood samples were again taken and the same analysis repeated. Apart from ADA2 activity, other enzyme activities were significantly high (p < 0.001), and serum Se concentrations were significantly low (p < 0.001) in animals of the white muscle disease group compared to the control group. When the parameters obtained from the white muscle disease group were compared before and after treatment it was indicated that all enzyme parameters decreased significantly (p < 0.001) after treatment. On the other hand, serum Se concentration increased (p < 0.01) after treatment in the diseased group. The results confirm that determining ADA serum and its isoenzymes, together with CK, LDH and AST values seems to be useful in diagnosing white muscle disease.
Serum Potassium-Lowering Effects of Insulin Plus Dextrose and Adrenalin Treatment That Enhance Intracellular Potassium Transitions in Hyperkalemic Diarrheic Calves
(Univ Agriculture, Fac veterinary Science, 2016) Altug, N.; Yuksek, N.; Ozkan, C.; Basbugan, Y.; Keles, I.; Agaoglu, Z. T.; Akgul, Y.
The study examined the serum potassium-lowering effects of different treatment options for hyperkalemia in diarrheic calves (n=18). Calves were allocated into three treatment groups. All groups received isotonic sodium bicarbonate solution for a period of 90 minutes. The animals in group 1 received no further treatment, those in group 2 received a further dose of 50% dextrose and insulin, and those in group 3 received a further dose of adrenaline. High serum K levels in all groups significantly decreased after treatment (AT) than before treatment (BT). Serum potassium levels AT in groups 2 and 3 were found to be significantly lower than those in group 1. Increase in pH, bicarbonate and total carbon dioxide values were observed AT in all groups. However, bicarbonate and total carbon dioxide levels in the AT were not statistically significantly different from those in the adrenaline group compared with the groups 1. These parameters were significantly lower in the group 2. Moreover, the concentration of glucose in the groups 2 in contrast to the adrenalin group was higher than that in both the BT and group 1 AT. The insulin + dextrose combination and adrenaline applications in hyperkalemic calves had similar effects. However, the administration of adrenaline had a lower negative effect on metabolic acidosis treatment. (C) 2015 PVJ. All rights reserved