YYÜ GCRIS Basic veritabanının içerik oluşturulması ve kurulumu Research Ecosystems (https://www.researchecosystems.com) tarafından devam etmektedir. Bu süreçte gördüğünüz verilerde eksikler olabilir.

Browsing by Author "Akbal, Damla"

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    Article
    Clinical Comparison of the Use of Er,cr:ysgg and Diode Lasers in Second Stage Implant Surgery
    (Saudi Med J, 2019) Tunc, Serap K.; Yayli, Nazli Z.; Talmac, Ahmet C.; Feslihan, Erkan; Akbal, Damla
    Objectives: To compare the effects of diode and erbium, chromium: yttrium-scandium-gallium-garnet (Er,Cr:YSGG) lasers in second-stage implant surgery applications. Methods: This is a cross-sectional study that was carried out on patients who received implant treatment at the Departments of Oral and Maxillofacial Surgery and Periodontology, Van Yuzuncu Yil University, Van, Turkey between January 2017 and January 2018. Implants of the patients in the first group (n=20) were exposed with 940 nm Ga-Al-As diode laser while the implants of the second group (n=20) were uncovered with 2780 nm Er,Cr:YSGG laser in the second-stage surgery. Visual analogue scale (VAS) values during day 0 and following the operation on days 1, 2, 3 intraoperative bleeding grades, number of analgesics used in the postoperative period, operation time per implant, and postoperative complications were recorded. Results: When gender, smoking, the presence of systemic disease, toothbrushing frequency, analgesic use, bleeding and complications observed at the control session were analyzed, no statistically significant relationship was found between the 2 groups. It was observed that males had statistically significant higher VAS values than females (p<0.05). Conclusion: Since diode lasers are more economical, smaller, and can meet the clinical needs of clinicians, it is likely that these lasers may be the preferred choice of the clinicians in surgical procedures.
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    Article
    Erbium, Chromium-Doped: Yttrium, Scandium, Gallium, Garnet and Diode Lasers in the Treatment of Peri-Implantitis: Clinical and Biochemical Outcomes in a Randomized-Controlled Clinical Trial
    (Springer London Ltd, 2022) Alpaslan Yayli, Nazli Zeynep; Talmac, Ahmet Cemil; Keskin Tunc, Serap; Akbal, Damla; Altindal, Dicle; Ertugrul, Abdullah Seckin
    This study aims to evaluate the effects of 940 nm diode laser and 2780 nm erbium, chromium-doped: yttrium, scandium, gallium, garnet (Er,Cr:YSGG) laser used in addition to mechanical therapy in the non-surgical treatment of peri-implantitis on clinical parameters and matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels in the peri-implant crevicular fluid. A total of 50 patients with peri-implantitis were randomized into three groups to receive peri-implant treatment. The control group (n = 17) only received conventional non-surgical mechanical therapy. The trial groups [(diode group (n = 16) and Er,Cr:YSGG group (n = 17)] received dental laser in addition to mechanical therapy. Gingival index (GI), plaque index (PI), bleeding on probing, probing depth (PD), MMP-9, and TIMP-1 levels were assessed at baseline (T0) and at 6 months after treatment (T1). The GI, PI, and PD significantly decreased in all groups at T1, compared to T0 (p < 0.05). The decrease in the PD was similar between the control and diode groups with Er,Cr:YSGG providing more reduction (1.16 +/- 0.64 mm) than either method (p = 0.032). A significant intra-group decrease in MMP-9 level was only observed in the Er,Cr:YSGG group (p = 0.009). The decrease in TIMP-1 level from T0 to T1 was similar between the control and the diode groups (p > 0.05) and it was significantly lower than the decrease in the Er,Cr:YSGG group (p < 0.05). Addition of diode laser to non-surgical mechanical therapy does not provide any additional benefit for treatment outcomes. The Er,Cr:YSGG laser seems to be more efficient both at clinical and molecular levels.
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    Article
    Evaluation of Biochemical and Clinical Effects of Hyaluronic Acid on Non-Surgical Periodontal Treatment: a Randomized Controlled Trial
    (Springer London Ltd, 2020) Aydinyurt, Hacer Sahin; Akbal, Damla; Altindal, Dicle; Bozoglan, Alihan; Ertugrul, Abdullah Seckin; Demir, Halit
    Background Recent studies reported that hyaluronic acid (HA) has anti-inflammatory, anti-edematous, and anti-bacterial activities in dentistry, particularly in gingival disorders caused by subgingival plaque microorganisms. Aims This study aimed to evaluate the early term effects of HA as an adjunct to scaling and root planing (SRP) on clinical parameters, periodontal inflamed surface area (PISA), and adenosine deaminase (ADA), catalase (CAT), and glutathione (GSH) levels in gingival crevicular fluid (GCF) in periodontitis. Methods A total of 24 periodontitis patients per group were included in this randomized-controlled study. The study population was divided into four groups: in Group 1: SRP+ saline; in Group 2: SRP + HA gel; in Group 3: SRP+ HA mouth rinse; and in Group 4: SRP + HA mouth rinse + HA gingival gel were applied. At baseline and week 4, clinical parameters and PISA were calculated. Also, biochemicals' (ADA, CAT, and GSH) levels were determined by spectrophotometric analysis. Results There was a statistically significant improvement in clinical parameters and PISA in all four groups in control sessions (p < 0.05). There was a significant decrease in ADA in GCF and significant increases in CAT and GSH levels after SRP (p < 0.05) in all four groups. The groups that were administered only gel (2nd and 4th) were different from other groups in terms of ADA, CAT, and GSH levels at 1st week (p < 0.05). Conclusion HA application as an adjunct to SRP did not affect the clinical results, although, in the control sessions following the application, the results were favorable for the biochemical data in gel-applied groups.
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    Article
    Evaluation of the Effect of Er,cr:ysgg Laser Application on Peri-Implant Crevicular Fluid Receptor Activator of Nuclear Factor-Kappa B Ligand and Osteoprotegerin Levels in the Non-Surgical Treatment of Peri-Implantitis: a Randomized Clinical Trial
    (Wiley, 2024) Alpaslan, Nazli Zeynep; Altindal, Dicle; Akbal, Damla; Talmac, Ahmet Cemil; Tunc, Serap Keskin; Ertugrul, Abdullah Seckin
    Background: This study aimed to investigate the effect of erbium, chromium doped:yttrium,scandium,gallium,garnet (Er,Cr:YSGG) laser application combined with non-surgical mechanical debridement (MD) on clinical parameters and peri-implant crevicular fluid receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin (OPG) levels in the treatment of peri-implantitis. Methods: A total of 49 patients who underwent non-surgical treatment of peri-implantitis were randomly divided into two groups. The control group (n = 26) received MD alone, while the laser group (n = 23) received MD+Er,Cr:YSGG. The clinical parameters (bleeding on probing [BoP], gingival index [GI], plaque index [PI], probing depth [PD]), marginal bone loss (MBL), and biochemical parameters (RANKL and OPG) were measured at baseline (T0) and 6 months after treatment (T1). Results: There was a statistically significant decrease in all the clinical parameters in both groups at T1 compared to T0 (p < 0.05). The BoP, PD, MBL, and RANKL reductions were significantly higher in the laser group than in the control group (p = 0.046, p = 0.014, p = 0.047, p = 0.045, respectively). The OPG levels significantly increased at T1 in the laser group (p = 0.01). The OPG/RANKL ratio increased significantly in both groups at T1, which favored the laser group (p = 0.034). Conclusions: Although both treatment methods were influential in treating peri-implantitis, the laser group (MD+Er,Cr:YSGG) yielded more favorable results by reducing clinical inflammation and improving biochemical parameters. Based on these findings, Er,Cr:YSGG laser may be a beneficial adjunctive treatment in this patient group.
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    Doctoral Thesis
    Evaluation of the Effects of Diode Lasers Addition To Inital Periodontal Theraphy in the Treatment of Periodontitis
    (2019) Akbal, Damla; Alkan, Eylem Ayhan; Talmaç, Ahmet Cemil
    Bu çalışmanın amacı; periodontitis tanısı almış bireylerde, başlangıç periodontal tedavi uygulamasına ek olarak uygulanan diyot lazerin periodontal tedavideki etkinliğinin klinik periodontal indeksler (Gingival İndeks, Plak İndeksi, Sondlamada Kanama, Sondlanabilir Cep Derinliği, Klinik Ataçman Seviyesi) ve biyokimyasal belirteçler (TNF-α, IL-1β, CTX) açısından değerlendirilmesidir. Çalışmamıza, 22 sistemik olarak sağlıklı, periodontitis hastası dahil edilmiştir. Başlangıçta, 1, 3 ve 6. aylarda klinik periodontal parametreleri kaydedilmiş ve DOS örnekleri toplanmıştır. Rastgele seçilen çenelerin bir tarafını kontrol grubu bir tarafını lazer grubu oluşturmuştur. Kontrol grubunda yalnız kök yüzeyi düzleştirmesi uygulanmış, lazer grubunda ise kök yüzeyi düzleştirmesine ilave olarak diyot lazer uygulanmıştır. Çalışmamızda elde edilen sonuçlara göre, klinik parametrelerde her iki grupta da anlamlı bir düşüş izlenmiştir ancak gruplar arasında anlamlı bir fark izlenmemiştir.Biyokimyasal parametreler yönünden değerlendirildiğinde, TNF-⍺ ve IL-1ß seviyelerinde her iki grupta da başlangıç seviyelerine göre anlamlı bir düşüş meydana gelmiştir. CTXI seviyelerinde ise kontrol ve test grubunda istatistiksel olarak anlamlı bir fark gözlenmemiştir. Biyokimyasal parametreler yönünden gruplar arasında anlamlı bir fark ortaya çıkmamıştır. Çalışmamızın sonucunda, periodontitis tedavisinde diyot lazer uygulamasının klinik ve biyokimyasal parametreler açısından periodontal tedaviye istatistiksel olarak anlamlı bir yarar sağlamadığı izlenmiştir. Bu konuyla ilgili daha fazla araştırmaya ihtiyaç duyulmaktadır. Anahtar Kelimeler: Periodontitis, Diyot lazer, TNF-⍺, IL-1ß, CTXI