Browsing by Author "Akbayram, Sinan"

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A 3-Day Boy With a Right Preauricular Swelling
(Springer, 2010) Akgun, Cihangir; Peker, Erdal; Akbayram, Sinan; Dogan, Murat; Tuncer, Oguz; Kirimi, Ercan
A 3-day-old boy was admitted for right preauricular swelling. Examination showed a toxic looking neonate with poor neonatal reflexes. There was erythema and swelling of 4 x 3 cm at the level of the right cheek. Laboratory investigation pointed to a bacterial infection. With parenteral antibiotics, the lesion resolved completely.
Acquired Methemoglobinemia Due To Application of Prilocaine During Circumcision
(Elsevier Science inc, 2012) Akbayram, Sinan; Akgun, Cihangir; Dogan, Murat; Gundogdu, Mustafa; Caksen, Huseyin; Oner, Ahmet Faik
Acute Appendicitis in Two Children With Henoch-Schonlein Purpura
(Maney Publishing, 2012) Bilici, Salim; Akgun, Cihangir; Melek, Mehmet; Peker, Erdal; Akbayram, Sinan; Bulut, Gulay; Dogan, Murat
In Henoch-Schonlein purpura (HSP), involvement of the ileum and ascending colon with vasculitis can mimic appendicitis and cause unnecessary appendicectomy. A 13-year-old boy presented with signs of HSP and abdominal pain. He was treated with prednisolone (2 mg/kg/day) for 10 days, but there was no improvement. At laparotomy he had acute suppurative appendicitis. A 12-year-old girl presented with HSP associated with abdominal pain and bloody diarrhoea and at laparotomy was also found to have suppurative appendicitis. Both patients had vasculitic areas in the ileum. In HSP, although suppurative appendicitis is rare, it should always be considered and appropriate investigations, including ultrasonography, undertaken.
Acute Cyanide Intoxication Due To Apricot Seed Ingestion
(Elsevier Science inc, 2013) Akil, Muhammed; Kaya, Avni; Ustyol, Lokman; Aktar, Fesih; Akbayram, Sinan
Acute Hepatotoxicity Due To Clonazepam in a Girl Using Oxcarbazepine
(Elsevier Science Bv, 2013) Akbayram, Sinan; Aktar, Fesih; Akgun, Cihangir; Caksen, Huseyin
Acute Immune Thrombocytopenic Purpura Following Oral Polio Vaccination
(Taylor & Francis inc, 2015) Akbayram, Sinan; Karaman, Kamuran; Ece, Ibrahim; Akbayram, Tuba Hatice
Acute Itp Due To Insect Bite: Report of 2 Cases
(Sage Publications inc, 2011) Akbayram, Sinan; Akgun, Cihangir; Dogan, Murat; Caksen, Huseyin; Oner, Ahmet Faik
Immune thrombocytopenic purpura (ITP) of childhood is a common hematologic disorder. Immune thrombocytopenic purpura is characterized by increased destruction of antibody-coated platelets in the reticuloendothelial system. In the majority of children with acute ITP, thrombocytopenia occurs within 1 to 3 weeks after an infectious disease. Immune thrombocytopenic purpura may also occur after rubella, rubeola, chickenpox, or live virus vaccination. Here we report 2 cases with acute ITP that were developed after honeybee and insect bite.
Acute Respiratory Distress Syndrome Occurred After Hanging Result of the Attached To Rope: a Case Report
(Aves, 2012) Kaya, Avni; Okur, Mesut; Akbayram, Sinan; Avcu, Serhat; Acikgoz, Mehmet; Dogan, Murat; Akil, Muhammed
A-13-year-old male patient was admitted to our emergency unit because of near-hanging while playing with a rope. On physical examination, his general condition was not good, his state of consciousness was evaluated to be stuporous and his spontaneous respiration was weak. The patient had been intubated. The Glasgow coma score was 7. Rope marks were observed on his neck. Thorax computed tomography revealed widespread ground-glass appearance and bilateral parenchymal consolidation in the lungs. This findings correlated with acute respiratory distress syndrome. This case was reported for reminding that acute respiratory distress syndrome can be associated with near-hanging. (Turk Arch Ped 2012; 47: 302-4)
Akut İnfantil Hemorajik Ödem: İki Olgunun Sunumu
(2016) Karaman, Kamuran; Akbayram, Sinan; Öner, Ahmet Faik; Garipardıç, Mesut
Akut infantil hemorajik ödem, üç yaşından küçük çocuklarda, seyrek görülen, derinin lökositoklastik vaskülitidir. Hastalık kendini sınırlar ve iyi klinik seyre sahiptir. Çalışmada; deride purpurik döküntü ve ekstremitelerde ödem yakınmaları ile başvuran, klinik ve laboratuvar incelemeleri sonucunda akut infantil hemorajik ödem tanısı almış iki olgu sunulmuştur. Klinik izlem ve tedavi açısından farklı yaklaşımlar gerektiren özellikle Henoch-Schönlen purpurası, meningokoksemi, purpura fulminans gibi hastalıklarla ayırıcı tanıda akut infantil hemorajik ödemin de düşünülmesi gerektiğini vurgulamak istedik.
An Analysis of Children With Brucellosis Associated With Isolated Thrombocytopenia
(Sage Publications inc, 2011) Akbayram, Sinan; Dogan, Murat; Akgun, Cihangir; Peker, Erdal; Parlak, Mehmet; Oner, Ahmet Faik
Hematologic abnormalities of mild anemia and leucopenia have been frequently associated with acute brucellosis, but thrombocytopenia are less frequently seen. In the present study, we documented 5 (2.6%) isolated thrombocytopenic patients with the manifestations of brucellosis observed during the course of active infection. Five (2.6%) patients, 4 boys and 1 girl, with ages ranging from 2 to 14 years, had isolated thrombocytopenic at diagnosis. In 5 (2.6%) patients, platelet counts ranged from 39 000 to 120 000/mm(3). Tube agglutination tests for brucellosis were positive for all patients (1/160-1/1280). All patients recovered completely, and their thrombocytopenia returned to normal by 2 to 4 weeks after antibiotic treatment of brucellosis. In our study, we present 5 patients with Brucella-induced thrombocytopenia mimicking idiopathic thrombocytopenic purpura to emphasize the isolated thrombocytopenia and the resolution of thrombocyte counts following treatment of brucellosis.
An Analysis of Children With Brucellosis Associated With Pancytopenia
(informa Healthcare, 2011) Akbayram, Sinan; Dogan, Murat; Akgun, Cihangir; Peker, Erdal; Parlak, Mehmet; Caksen, Huseyin; Oner, Ahmet Faik
Brucellosis produces a variety of nonspecific hematologic abnormalities. Hematologic complications of mild anemia and leukopenia have been frequently associated with acute brucellosis, but pancytopenia is less frequently seen. In this study, records of children with brucellosis aged under or equal to 16 years, admitted to Yuzuncu Yil University Hospital between 2004 and 2010, were analyzed retrospectively. Over this time period, 187 patients with brucellosis were diagnosed. Twenty-five (13.3%%) of 187 patients had pancytopenia during admission to hospital. The diagnosis of brucellosis was confirmed by standard tube agglutination test in all patients; titers were 1:320 in 1 patient and 1:1280 in 24 patients. Blood culture was positive for Brucella melitensis in 3 patients (12%%). Fever was the most common manifestation, followed by malaise, anorexia, sweating, and weight loss. Fever and splenomegaly were the common signs in most patients. In addition, arthritis was observed in 5 patients, and epistaxis, headache, and abdominal pain were observed in 3 patients. The common bone marrow aspiration findings consisted of increased megakaryocytes and hyperplasia of erythroid series, with a shift to the left of the granulocytic series. Histiocytic hyperplasia was observed in the bone marrow smear of 2 patients. Mild hemophagocytosis was observed in the bone marrow of 3 patients. All patients recovered completely, and their peripheral blood counts returned to normal by 2 to 6 weeks after antibiotic treatment of brucellosis. In conclusion, the authors would like to emphasize that brucellosis should be considered in the differential diagnosis of children with pancytopenia.
The Association Between Hla Class I and Ii Alleles and The Occurrence of Inhibitors in Turkish Patients With Hemophilia A: a Pilot Study
(Wiley, 2019) Patiroglu, Turkan; Cansever, Murat; Akbayram, Sinan; Gulen, Huseyin; Oncel, Kahraman; Borst, Ozcan; Kavakli, Kaan
The Association of Oxidant Status and Antioxidant Capacity in Children With Acute and Chronic Itp
(Lippincott Williams & Wilkins, 2010) Akbayram, Sinan; Dogan, Murat; Akgun, Cihangir; Mukul, Yurdaguel; Peker, Erdal; Bay, Ali; Oner, Ahmet Faik
Purpose: This study was undertaken to investigate oxidant and antioxidant systems in patients with immune thrombocytopenic purpura (ITP). With this purpose, we measured the levels of serum malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), and other oxidative stress parameters. Patients and Methods: Fifty-two pediatric patients with ITP (25 acute, 27 chronic) and 21 healthy children were included in the study. Patients with acute ITP were studied, before and after, methylprednisolone treatment. Results: Hemoglobin, hematocrit, platelet count, and TAC were statistically significantly lower in patients with acute ITP before treatment than those in the control group (P<0.05). In addition, in this group, MDA, TOS levels, and OSI (oxidative stress index) were found to be higher than those in the control group. In chronic ITP group, although hemoglobin hematocrit, platelet counts, and TAC levels were statistically significantly lower than those in the control groups, the mean platelet volume, MDA, TOS, and OSI were found to be statistically significantly higher (P<0.05). Platelet count and mean platelet volume values were statistically significantly lower in patients with acute ITP before treatment than after treatment (P<0.05). We also found a positive correlation between thrombocyte count and TAC, in patients with acute ITP before treatment (r: 0.601, P<0.001) and acute ITP after treatment (r: 0.601, P<0.001) and chronic ITP (r: 0.601, P<0.001). A negative correlation was found between thrombocyte count and serum MDA levels, in patients with acute ITP before treatment (r: -0.356, P<0.001) and acute ITP after treatment (r: -0.356, P<0.001) and chronic ITP (r: -0.356, P<0.001). We also found a negative correlation between thrombocyte count and serum OSI, in patients with acute ITP before treatment (r: -0.494, P<0.001) and acute ITP after treatment (r: -0.494, P<0.001) and chronic ITP (r: -0.494, P<0.001). A negative correlation was found between thrombocyte count and TOS, in patients with acute ITP before treatment (r: -0.470, P<0.001) and acute ITP after treatment (r: -0.470, P<0.001) and chronic ITP (r: -0.470, P<0.001). In conclusion, increased MDA, TOS and OSI, and decreased TAC levels were found in patients with acute and chronic ITP. Conclusions: On the basis of these findings, we suggest that free oxygen radicals may have an effect on the structural and functional damage of platelets, and on the mechanism of thrombocytopenia in both, acute and chronic ITP.
Atipik Seyirli Subakut Sklerozan Panensefalitli İki Çocuğun Sunumu
(2003) Odabaş, Dursun; Atas, Bulent; Akbayram, Sinan; Çaksen, Hüseyın; Tepebaşılı, İbrahim
Bu makalede nadir görülmesi nedeniyle atipik seyirli subakut sklerozan panensefalitli (SSPE) iki olgu sunuldu. Yedi yaşında kız hasta ilk kez yedi gün önce başlayan yürüme ve konuşma bozukluğu şikayetleriyle getirildi. Üç gün sonra afazi ve ataksik yürüyüşü kendiliğinden düzeldi, klinik ve nörolojik muayenesi normal olarak tespit edildi. Ancak müracaatın 14. gününde miyoklonik jerkleri ortaya çıktı. Serum ve beyin omurilik sıvısında kızamık virüsüne karşı IgG antikorları pozitif bulundu. SSPE teşhisi kondu ve spesifik tedavi başlandı. Şu anda hasta takibinin dokuzuncu ayında ve III. evrede izlenmektedir. İkinci vaka 3 yaşında erkek çocuk ilk kez bir ay önce yürüyememe ve konuşamanıa şikayeti ile başvurdu. Kızamık IgG antikorları, pozitif bulunduğundan dolayı SSPE tanısı kondu ve spesifik tedavi başlandı. Ancak izleminin altıncı haftasında hasta kaybedildi.
Atypical Presentation of Herpes Zoster in a Case With Acute Myeloblastic Leukemia
(Elsevier Science Bv, 2013) Aktar, Fesih; Akbayram, Sinan; Akdeniz, Necmettin; Aktar, Sirac; Akgun, Cihangir; Dogan, Murat; Oner, Ahmet Faik
Herpes zoster (HZ) is often associated with painful erythematous vesicular eruptions of the skin or mucous membranes. Approximately 10% to 30% of the population will suffer from HZ during their lifetime. HZ is infrequent in healthy children. However, diminished cellular immunity seems to increase risk of reactivation because incidence increases with age and in immunocompromised states. We report a 7 year old girl with acute myeloblastic leukemia HZ infection on the right palmar, elbow and forearm region (C7, C8 and T1 dermatomes). We want to indicate unusual localization of HZ on the acute myeloblastic leukemia child patient.
Beckwith-Wiedemann Sendromu Ve Uzamış Hipoglisemi
(2010) Kırımi, Ercan; Peker, Erdal; Tuncer, Oğuz; Akbayram, Sinan
Beckwith-Wiedemann sendromu (BWS), makrosomi, makroglossi, karın duvar defektleri, hemihipertrofi ile karakterize prenatal veya postnatal bir aşırı büyüme sendromudur. Hastalığın komplikasyonları arasında wilms tümörü, rabdomyosarkom, nöroblastom gibi embriyonal kanserlerle ve hipoglisemi sayılmaktadır. BWS’lu bebeklerin yaklaşık %30’unda hipoglisemi rastlanmaktadır. Hipoglisemi nedeni tam olarak bilinmemekte ve hiperinsülinemi suçlanmaktadır. BWS’da hipoglisemi genellikle yaşamın ilk üç gününden sonra iyileşmesine rağmen vakaların %5’inde dirençli hipoglisemi devam etmektedir. Sonuç olarak BWS’lu bebeklerde kan şekeri düzeyleri ilk saatlerden itibaren düzenli izlenmeli ve insülin düzeyleri de kontrol edilmelidir. Hiperinsülinemi varlığında hipoglisemi problemi burada sunulan vakada olduğu gibi uzayabilir.
Benidipine Hydrochloride Intoxication in a Child
(Elsevier Science inc, 2012) Akbayram, Sinan; Akgun, Cihangir; Dogan, Murat; Geylani, Hadi; Sari, Nesim; Taskin, Alparslan Gokmen; Caksen, Huseyin
Brusellozda Akciğer Tutulumu
(2010) Bektaş, M. Selçuk; Peker, Erdal; Akbayram, Sinan; Doğan, Murat; Öner, A. Faik
Bruselloz, gram-negatif bakteri ailesinden Brusella türü bakterilerle oluşan zoonotik bir hastalıktır. Bruselloz, dünya genelinde özellikle gelişmekte olan ülkelerde bir halk sağlığı sorunu olarak görülmeye devam etmektedir. Bakteri başta retiküloendotelyal sistem olmak üzere eklem, kalp, böbrek gibi pek çok sistemi tutabilir. Solunum sistemini tuttuğu bilinmesine rağmen akciğer tutulumu nadirdir. Akciğer tutulumu olan hastalarda klinik bulguların ve komplikasyonların nonspesifik olması tanı koymayı zorlaştırmaktadır. Bu olgu sunumunda, ateş yüksekliği, öksürük, balgam çıkarma, hemoptizi, halsizlik, istahsızlık, dizlerde ağrı şikâyetiyle başvuran 6 yaşındaki erkek hasta pnömoni ve plevral efüzyon tanılarıyla yatırıldı. Yapılan tetkiklerinde hepatosplenomegali ve bisitopeni saptanan olgunun alınan kan ve plevral efüzyon mayisinden Rose- Bengal testi (+++) ve Wright agglütinasyon testi 1/1280 (+) saptandı. Olgu brusellaya bağlı pnömoni ve plevral effüzyon olarak kabul edildi. Olgu nadir görülmesi ve ülkemiz gibi brusellanın endemik olduğu ülkelerde brusellaya bağlı komplikasyonların geniş bir yelpazede olduğunu vurgulamak üzere sunuldu.
Burkitt's Lymphoma Causing Acute Pancreatitis in a Child
(Elsevier Science Bv, 2013) Akil, Muhammed; Kaya, Avni; Bektas, M. Selcuk; Aktar, Fesih; Akbayram, Sinan; Bilici, Salim; Beyazal, Mehmet
A 8-year-old boy admitted with abdominal pain, fever and vomiting for the previous 10 days. Sensitivity was detected in the epigastric area. There was not defense and rebond. Aspartate aminotransferase was 106 U/L, alanine aminotransferase 25 U/L, alkaline phosphatase 311 U/L, blood amylase level 748 U/L, blood lipase level 391 U/L. In thoracic CT, soft tissue with smooth contours measuring 32 mmx28 mm was identified in the posterior mediastinum. Bone marrow aspiration biopsy was normal. A mass specimen obtained from the duodenum endoscopic biopsy. This specimen was diffuse staining by leukocyte common antigen, CD10 and CD20. The patient was diagnosed with acute pancreatitis associated with stage 3 duodenal Burkitt's lymphoma. Modified LMB-98 was initiated. Burkitt's lymphoma may rarely cause acute pancreatitis.
A Case of Atypical Brucellosis Presented With Isolated Lymphadenopathy
(Aves Yayincilik, Ibrahim Kara, 2017) Karaman, Kamuran; Akbayram, Hatice Tuba; Akbayram, Sinan; Garipardic, Mesut; Oner, Ahmet Fayik
Brucellosis is transmitted via animal or animal products. The transmission of infection from animal to human occurs by the ways of; generally the direct contact of secretions of infected animals through the human skin which of broken integrity, consumption of unpasteurized milk and milk products, inhalation and contact with conjunctiva with infected aerosols. The infection can be presented with variable manifestations and involment of cardiovascular, central nervous system, skeletal system, skin and gastrointestinal system. It is generally a disease with good prognosis; but the complicated involvement like of bone, cardiovascular and menegial site leads to significant morbidity and mortality. Here, we presents a case of brucella lymphadenitis of 9 years old patiens in whom admitted with isolated lmphadenopathy and recovered clinically and laboratory upon starting the treatment for brucellosis.