Browsing by Author "Akdemir, Ramazan"

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Changes in Serum Natriuretic Peptide Levels After Percutaneous Closure of Small To Moderate Ventricular Septal Defects
(Hindawi Publishing Corporation, 2012) Kaya, Yuksel; Akdemir, Ramazan; Gunduz, Huseyin; Murat, Sani; Bulut, Orhan; Kocayigit, Ibrahim; Acar, Zeydin
Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on brain natriuretic peptide levels. Methods. Between 2008 and 2011, 23 patients underwent successfully percutaneous ventricular septal defect closure in 4 cardiology centers. Brain natriuretic peptide levels were measured in nine patients (4 male, mean ages were 25.3 +/- 14.3) who underwent percutaneous closure with Amplatzer occluders for membranous or muscular ventricular septal defects were enrolled in the study. Brain natriuretic peptide levels were measured one day before and one month after the closure. Patients were evaluated clinically and by echocardiography one month after the procedure. Results. Percutaneous closures of ventricular septal defects were successfully performed in all patients. There was not any significant adverse event in patients group during followup. Decrease in brain natriuretic peptide levels after closure were statistically significant (97.3 +/- 78.6 versus 26.8 +/- 15.6, P = 0.013). Conclusion. Brain Natriuretic Peptide levels are elevated in patients with ventricular septal defects as compared to controls. Percutaneous closure of Ventricular Septal Defect with Amplatzer occluders decreases the BNP levels.
Native Aortic Coarctation Stenting in Adults and Adolescents: Early and Mid-Term Results of an Adult Interventional Cardiology Team
(Termedia Publishing House Ltd, 2012) Akdemir, Ramazan; Gunduz, Huseyin; Murat, Sani; Kilic, Harun; Yeter, Ekrem; Agac, Mustafa Tarik; Erdem, Ali Fuat
Background: Stent implantation has evolved as an important therapeutic strategy for aortic coarctation. Aim: This study aimed to present the experience of aortic coarctation stenting using the Cheatham-Platinum stent by an Adult Interventional Cardiology Team. Material and methods: The data of 11 patients (ages were between 15 to 58 years) who underwent aortic coarctation stent implantation between 2008 and 2011 for moderate to severe native aortic coarctation were retrospectively collected. Results: Average systolic blood pressure was 175 +/- 35 mm Hg, and mean diastolic blood pressure was 115 +/- 15 mm Hg. Pressure gradient proximal and distal to aortic coarctation was 55.5 +/- 17.7 before the stenting. The invasive gradient decreased below 10 mm Hg in all patients. There were no complications except in one patient whose subclavian artery was occluded without any clinical finding. One patient had a totally occluded lesion, needing perforation for acquired interruption using a 0.35 inch hydrophilic wire under the supporting balloon. There was no aneurysm or restenosis at follow-up. Left ventricular functions completely recovered within 1 month in all patients. Conclusions: Stenting using the Cheatham-Platinum stent, either covered or bare, is safe in moderate to severe native aortic coarctation and provides an excellent transcoarctation gradient and clinical hypertension and left ventricular functional relief in adult patients.