Browsing by Author "Akkan, H.A."

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Investigation of Anti-Inflammatory Activity of Bergamot Oil
(TIP ARASTIRMALARI DERNEGI, 2007) Karaca, M.; Özbek, H.; Him, A.; Tütüncü, M.; Akkan, H.A.; Kaplanoǧlu, V.
Aim: Essential oil of Bergamot (BO) was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test. Methods: For the anti-inflammatory activity measurement six different groups were established and BO was administered in three different doses: 0.025, 0.05 and 0.10 mL/kg. Indomethacin was used as a reference agent. Results: It was found that reduction in the inflammation was 95.70% with indomethacin, 27.56% with 0.025 mL/kg BO, 30.77% with 0.05 mL/kg BO and 63.39% with 0.10 mL/kg BO. Indomethacin showed the strongest anti-inflammatory activity among the drugs used. The strongest anti-inflammatory activity of BO was seen with 0.10 mL/kg dosage. Median effective dose (ED50) value of BO was found to be 0.079 mL/kg. Conclusion: The results showed that BO posseses promising anti-inflammatory effect.
The Seroprevalance of Toxoplasma Gondii in Sheep, Goats and Cattle Detected by Indirect Haemaglutination (Iha) Test in the Region of Van, Turkey
(2003) Tutuncu, M.; Ayaz, E.; Yaman, M.; Akkan, H.A.
This study was carried out on sheep, goats and cattle in order to determine the seroprevalence of toxoplasmosis in the province of Van. Indirect Haemaglutination (IHA) test was used to detect Toxoplasma gondii antibodies in 305 ruminants (150 sheep, 104 cattle and 51 goats) obtained from the city center of Van and its region. The sera were tested for Toxoplasma gondii antibodies between 32 and 1024 titres. Samples with titres 64 and greater than this were considered as positive. The prevalaence of the positive sera were found to be 52 (34.6%) for sheep, 8 (7.6%) for cattle and 17 (33.3%) for goats. The results indicate that Toxoplasma gondii infection in ruminants in the province of Van is widespread.