Browsing by Author "Aksoy, A"

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Accidental Salinomycin Intoxication of Angora Goats in Turkey
(Elsevier Science Bv, 2002) Agaoglu, ZT; Akgul, Y; Keles, I; Ugras, S; Aksoy, A; Cinar, A
This paper reports for the first time accidental intoxication of Angora goats with salinomycin contaminated feed in Turkey. Clinical, laboratory and postmortem findings are described. Angora goats were examined clinically and biochemical analysis of blood, electrocardiogram and histopathological examinations were carried out. The feed was shown to contain 680 ppm/kg of salinomycin. (C) 2002 Elsevier Science B.V. All rights reserved.
Comparison of the Pharmacokinetics of Conventional and Long-Acting Formulations of Oxytetracycline in Sheep
(Scientific Technical Research Council Turkey, 2001) Kaya, S; Yarsan, E; Baydan, E; Akkaya, R; Aksoy, A
The pharmacokinetics of conventional and long-acting oxytetracycline (OTC) formulation were evaluated in sheep at a single dosage of 20 mg-kg(-1) body weight (bw). Conventional formulation was injected by intravenous (IV) route and long-acting formulation of oxytetracycline was administered by intramuscular (IM) route, Then blood samples were taken at 0.25, 0.5, 1, 2, 4, 8, 12, 24, 36, 48, 60, 72, 84 and 96 hours. Oxytetracycline analysis was performed by HPLC in plasma. The plasma drug concentration-time profile was characteristic of a two-compartment open model. Following IM administration, time to reach maximal plasma drug concentration was 2 hours and maximal plasma drug concentration was 5.13 +/-0.31 mug/ml. After IV and IM administration of oxytetracycline, the elimination times were 1.14 +/-1.13 and 18.92 +/-1.86 hours, respectively. Intramuscular bioavailability was found to be 73%. Also, AUC was found to be 106.24 +/-8.92 and 78.92 +/-5.07 mug- ml(-1) hours', respectively, IV and IM.
Determination of Aflatoxin Levels in Some Dairy and Food Products Which Consumed in Ankara, Turkey
(Elsevier Sci Ltd, 2005) Aycicek, H; Aksoy, A; Saygi, S
Two hundred and twenty-three samples of dairy products (49 samples of cheese, 94 samples of white cheese, 53 samples of Kashar cheese, and 27 samples of butter), 51 dehulled hazelnut and 40 cacao hazelnut cream, marketed in Ankara, Turkey during September 2002-September 2003, were analysed for aflatoxin M1 (AFM1), total aflatoxin and AFB1 by microtitre plate enzyme-linked immunosorband assay (ELISA). The incidence of AFM1 contamination in dairy products analysed was 90.58%. AFB1 contamination was detected in 43 (84.32%) of dehulled hazelnut samples (ranging from <1 to 10 ppb) and in 38 (95%) samples of cacao hazelnut cream (ranging from <1 to 13 ppb). Total aflatoxin contamination was determined in 47 (92.16%) of dehulled hazelnut samples and in 39 (97.5%) samples of cacao hazelnut cream. AFM1 levels in 19 (8.52%) of 223 dairy product samples were determined higher than maximum tolerable limit of the Turkish Food Codex, whereas total aflatoxin levels in only one of 51 dehulled hazelnut and one of 40 hazelnut cacao cream samples were exceeded the legal limit. Continuous surevillance programme may be warranted to monitor regularly the occurrence of aflatoxins in foods and foodstuffs which consumed by human. (C) 2004 Elsevier Ltd. All rights reserved.
The Nitrate and Nitrite Levels of the Tubers of Potato Plant Fertilized With Different Doses
(Scientific Technical Research Council Turkey, 1999) Aksoy, A; Türel, I; Arslan, B; Dede, Ö
In this research,,This study was conducted to determine the effects of nitrogen forms (ammonyum nitrate, ammonyum sulphate and urea) and nitrogen doses (0. 7, 14, 21 and 28 g/m(2)) on nitrate and nitrite levels in potato cultivars (Caspar and Kondor). It was found that the levels of nitrate and nitrite obtained from the experiment did not exceed the accepted tolerance limits of 300 mg/g. However, differences among cultivars and nitrogen doses were found to be significant (p<0.05 and p<0.01, respectively) in terms of nitrate levels. The lowest nitrate levels were found in the caspar cultivar and the control. On the other hand, differences among nitrogen forms were found to be significant (p<0.05) in terms of nitrite levels. The highest nitrite levels was determined in ammonyum sulphate (27.67 ppb).