Browsing by Author "Aksu, Devrim Saripinar"

Now showing 1 - 5 of 5

The Effect of Chemical and Surgical Castration on the Live Weight Gain and Some Hormones of Male Norduz Sheep
(Zoological Soc Pakistan, 2017) Karakus, Kadir; Comba, Bahat; Tas, Abuzer; Sancak, Tunahan; Comba, Arzu; Aksu, Devrim Saripinar; Tariq, Mohammad Masood
The aim of this study was to investigate the effects of surgical and chemical castration on body weight and some hormones. In the present study, 2.5-3-month-old weaned male Norduz sheep were used. The sheep were obtained in the year 2015 from Livestock Application and Research Directorate of Yuzuncu Yil University. The sheep were randomly allocated into three groups each of which contained 10 sheep. The groups were formed as; Group 1 The Control Group (No castration), Group 2 (Surgical castration group) and Group 3 (Chemical castration group), respectively. Blood sample was taken from vena jugularis of the animals before the application and every two months for a total of 4 times for 6 months and hormone analyses were performed. The order of statistical significance for TSH (thyroid stimulating hormone) were found as Surgical > Control > Formol (P<0.05). The order of statistical significance for growth hormone was Formol = Surgery > Control (P<0.05). In August month, the application factor was found to be significant only in testosterone (P<0.05). No significant difference between the control and surgical groups in testosterone was noted. In this study, although the application of different castration methods in 4-month-old male Norduz sheep resulted in changes in the blood hormone levels, it was determined that these changes did not affect body weight. In conclusion, the evaluation of the process in castrated six-month-old sheep revealed an increase in the body weight which was similar to that in the control group.
The Effect of Origanum Syriacum L. Extract and Carvacrol on the in Vitro Digestion, Estimated Digestion Values, Ammonia and Organic Acid Concentrations in the Fermentation Fluid of Lucerne Herbage
(Czech Academy Agricultural Sciences, 2022) Onel, Suleyman Ercument; Aksu, Taylan; Kara, Kanber; Aksu, Devrim Saripinar
The effects induced by medicinal aromatic plants in biological systems vary with the type and amount of bioactive substances these plants contain. Whether the purified form of the main chemical components of these plants, such as carvacrol and thymol, or plant volatile oils containing tens of bioactive compounds are more effective remains a question of debate. This study was aimed at providing a comparative assessment of the effects of Origanum syriacum L. (wild mountain thyme) volatile oil (OSVO) and one of its main components, carvacrol (CRV), on the in vitro ruminal degradability of lucerne herbage and methane production during the degradation of lucerne. For this purpose, wild thyme was harvested at the beginning of the flowering period, and the OSVO was extracted from the plant by steam distillation. Gas production assays were performed in five groups of ruminal fluid samples, one of which was maintained for control purposes, and the other four 40/60/80 mg/l of OSVO and 60 mg/l of CRV were added. Compared to the control group, in the samples with the added CRV and OSVO, the amounts of in vitro total gas and methane production were observed to have been affected, but no decrease was detected in the ruminal protozoa counts. The level of ammonia nitrogen was lowest in the groups, in which CRV and 40 mg/l of OSVO (P < 0.01) were added. The ruminal protozoa counts were not affected by the addition of CRV and OSVO. While the total volatile fatty acid (TVFA) and propionic acid (PA) concentrations in the in vitro fermentation fluid of lucerne herbage were low in all the groups, butyric acid was detected at a level of 40 mg/l in the group where CRV was added. The OSVO was ascertained to have induced dose-dependent alterations in the investigated in vitro digestion parameters. In result, CRV (60 mg/l) and OSVO (40 mg/l) were determined to have shown a relatively positive effect on the in vitro ruminal gas production. The anti-methano genic effect of the plant extracts was due to the decreased digestibility of the lucerne herbage. This can have a positive impact on the environment, but the same cannot be said for the animal nutrient use and animal performance.
The Effect of Royal Jelly on Levels of Tnf-Alpha and Oxidant-Antioxidant Systems in Experimental Rats Hypothyroidism
(Parlar Scientific Publications (p S P), 2020) Cibuk, Salih; Mert, Handan; Aksu, Devrim Saripinar; Mert, Nihat
Royal jelly is a product of bees and contains proteins, carbohydrates, fats, free amino acids, vitamins and minerals. In this study, the effect of royal jelly on TNF-alpha levels and oxidant-antioxidant systems in hypothyroid rats induced by propylthiouracil (PTU) were investigated. Forty rats were randomly divided into four groups each containing 10 rats as control, royal jelly, PTU and PTU + royal jelly groups. At the end of the experiment, hematological parameters, sT3, sT4 and serum lipid profile, levels of TSH, TNF-alpha, GSH, MDA, GSH-Px, SOD and CAT were determined. The levels of sT3 (p < 0.001) and sT4 (p < 0.001) were significantly decreased and TSH levels (p < 0.05) increased in PTU and PTU + royal jelly groups compared to control group. There was a decrease in triglyceride levels (p < 0.05) and an increase in LDL (p < 0.01), RBC (p < 0.05), HCT (p < 0.01) and HGB (p < 0.01) in PTU + royal jelly group compared to the PTU group. Levels of TNF-alpha, GSH and GSH-Px, CAT, SOD were not significantly different between groups. As a result, increase in oxidative stress was not detected in hypothyroid rats induced by PTU. Therefore we could not observe the effect of royal jelly on oxidative stress. In hypothyroidism, royal jelly had positive effects on triglycerides, RBC, HCT and HGB. Especially for the treatment of anemia in hypothyroidism royal jelly may be recommended. This is a preliminary study that shows the effect of royal jelly on hypothyroidism. There is a need for further studies on this issue.
Effect of Some Essential Oils on in Vitro Ruminal Fermentation of Alfalfa Hay
(Mattioli 1885, 2021) Onel, Suleyman Ercument; Aksu, Taylan; Kalamak, Adem; Kaya, Durmus Alpaslan; Aksu, Devrim Saripinar; Sakin, Fatib; Turkmen, Musa
Study Objectives: This study aimed to investigate the effects of essential oils derived from the leaves of Laurus nobilis (LNEO), Myrtus communis (MCEO), Lavandula stoechas (LSEO), Artemisia annua (AAEO), and Thymbra spicata (TSEO) on the rumen fermentation parameters (gas production, methane emission, organic acids, and the number of protozoa) of dry alfalfa hay. Methods: The components of all essential oils were analyzed. The effects of adding the same dose (60 mg/L) of each essential oil to the rumen fluid on in vitro rumen digestion were determined by in vitro gas production. Results: The addition of Lavandula stoechas, Artemisia annua, Myrtus communis, and Laura nobilis essential oils decreased the total gas and methane formation (ml), organic matter digestion (OMD), ruminal ammonia nitrogen levels, and the metabolic energy (ME) values. On the other hand, the Thymbra spicata essential oil did not affect any parameter except the ruminal ammonia nitrogen level. The rumen protozoa numbers were unaffected by the addition of Thymbra spicata essential oil. The total volatile fatty acids (TVFA), acetic acid (AA), propionic acid (PA), and butyric acid (BA) amounts in the in vitro fermentation fluid of alfalfa hay were low in all groups. Conclusion: It was determined that the active ingredients of LSEO, AAEO, MCEO, and LNEO may have a regulatory effect on ruminal fermentation. We think that more studies using different feed types and combinations of essential oils are required to reveal the effects of these essential oils on ecology and the physiology of the digestive system.
Ginkgo Biloba Extract (Egb 761) Protects the Mice Brain Against Fluoride-Induced Oxidative Stress
(Parlar Scientific Publications (p S P), 2014) Atmaca, Nurgul; Aksu, Devrim Saripinar; Yildirim, Ebru; Atmaca, H. Tarik
The aim of this study was to investigate the effects of Ginkgo biloba extract (EGb 761) on oxidative stress and the histopathological changes in brain tissues of mice exposed to fluoride administration. A total of 24 mice were divided into 4 groups as control, EGb 761, fluoride and fluoride+EGb 761, with 6 mice in each group. Control group received drinking water, fluoride group received 50 mg/L fluoride in drinking water, fluoride+EGb 761 group was given 50 mg/L fluoride in drinking water and 20 mg/kg EGb 761 orally by gavage, and EGb 761 group was given only 20 mg/kg EGb 761 orally by gavage for 30 days. At the end of the experimental period, the levels of malondialdehyde (MBA) and glutathione (GSH) as well as' the activities of superoxide dismutase (SOD) and catalase (CAT) were detected, and histopathological examination was conducted in the brain of mice. The results showed that the levels of MDA, GSH, and the activities of SOD and CAT in fluoride group were statistically higher than in the control group. However, no statistically significant difference was detected between fluoride+EGb 761 and control group. The neurodejenerative changes seen in fluoride group were not detected in fluoride+EGb 761 group. It was concluded that the toxic effect of fluoride was related to the formation of reactive oxygen species, and EGb 761 had a protective effect by preserving antioxidant enzymes activity in mice brain tissues. Ginkgo biloba extract also prevented the histopathological changes induced by fluoride administration.