Browsing by Author "Akyol, A."
Now showing 1 - 12 of 12
- Results Per Page
- Sort Options
Article Brucella Endocarditis Caused by Brucella Melitensis(2013) Akdag, S.; Akyol, A.; Simsek, H.; Şahin, M.; Yaman, M.We present a rare case of brucella endocarditis, forming a vegetation on the mitral valve. The definitive diagnosis has been made with clinical suspicion, positive serology, the demonstration of the vegetation with the echocardiography and with the production from the multiple blood culture of brucella melitensis and from the excised valve. Our patient has been successfully treated with specific antibiotherapy and the surgery of replacement of mitral valve. Our aim in presenting the case is to remind the infective endocarditis which is due to this factor in the regions like our country which is endemic for brucellosis.Article Clinical and Laboratory Features of Patients With Pericardial Effusion(2010) Gümrükçüoǧlu, H.A.; Akyol, A.; Tuncer, M.; Güneş, Y.; Beǧenik, H.; Akdaǧ, S.; Aǧirbaşli, M.Objectives: We reviewed patients who were diagnosed to have pericardial effusion (PE) over a four-year period to determine the causes of PE, clinical and laboratory features, and treatment modalities. Study design: Medical records of 136 patients (81 women, 55 men; mean age 55.8±18.7 years; range 8 to 90 years) admitted to our department with PE from August 2005 to August 2009 were reviewed. The diagnosis of PE was made by transthoracic echocardiography. Medical history, physical examination, electrocardiography, echocardiography, and laboratory findings and treatment methods were recorded. Results: The most frequent complaint was dyspnea (86.8%) and the most common physical examination finding was jugular venous distension (47.1%). The most common electrocardiographic and echocardiographic findings were tachycardia (47.8%) and mild PE (<1 cm) (63.2%), respectively. Chronic renal failure and malignant diseases were the primary causes of PE (25% and 22.8% respectively), followed by idiopathic cases (14%). Pericardial tamponade was detected in 34 patients (25%), of which the majority had malignant diseases (53%). Thirty-eight patients (27.9%) underwent interventional treatment (pericardiocentesis in 27, surgical drainage in 11), while 98 patients (72.1%) were followed-up with medical treatment. Mortality occurred in three patients with pericardial tamponade. Conclusion: The most common causes of PE in our cases were chronic renal failure and malignancies. The incidence of malignant PE is on the incline owing to increased life expectancy. Echocardiography is the primary imaging modality for the evaluation of PE.Conference Object The Effect of Low Sodium Dialysate on Ambulatory Blood Pressure Measurement Parameters in Patients Undergoing Hemodialysis(Oxford Univ Press, 2015) Akdag, S.; Akyol, A.; Cakmak, H. A.; Tosu, A. R.; Asker, M.; Yaman, M.; Gumrukcuoglu, H. A.Article Effects of Lowered Dialysate Sodium on Left Ventricle Function and Brain Natriuretic Peptide in Maintenance of Hemodialysis Patients(Sage Publications Ltd, 2017) Akyol, A.; Akdag, S.; Asker, M.; Gumrukcuoglu, H. A.; Duz, R.; Demirel, K. C.; Begenik, H.Introduction: Impaired diastolic flow is characterized by decreased left ventricular (LV) filling diastole, abnormal LV distensibility, or delayed relaxation. B-Type natriuretic peptide (BNP) is an indicator of various cardiovascular diseases and body volume status. The aim of this study was to determine whether the lowering of dialysate sodium (Na) levels is effective on LV systolic and diastolic parameters and BNP in the maintenance of hemodialysis patients. Materials and Methods: The study included 49 chronic hemodialysis patients. Left atrium (LA) diameter and LV ejection fraction, LV systolic and diastolic diameter, deceleration time (DT), pulmonary artery pressure (PAP), inferior vena cava diameter (IVCD), early diastolic transmitral flow (E) and late diastolic transmitral flow (A) velocities, E/A ratio, isovolumic relaxation time, peak early diastolic velocity (E), late diastolic velocity (A) of tissue Doppler mitral annulus, and flow propagation velocity of mitral inflow (V-p) were measured before and 6 months after hemodialysis with low Na dialysate. Results: Six months after low Na hemodialysis, a decrease was observed in echocardiographic parameters such as PAP and IVCD (p < 0.05, p < 0.001, and p < 0.001, respectively). However, a significant difference was not observed in LA diameter. In LV diastolic measurement of E and A waves, E/A ratio, DT, V-p, septal E and A, and lateral E and A exhibited significant improvement by low Na HD. BNP level was significantly reduced (p < 0.001). Conclusions: Lowered dialysate Na concentration improves PAP, IVCD, and LV diastolic properties assessed by mitral inflow filling, tissue Doppler velocity, and mitral inflow velocity propagation.Conference Object Levosimendan Accelerates Recovery in Patients With Takotsubo Cardiomyopathy(Oxford Univ Press, 2016) Yaman, M.; Arslan, U.; Kaya, A.; Akyol, A.; Ozturk, F.; Okudan, Y. EmreArticle Maternal, Fetal Outcome, and Anticoagulant Management in Pregnant Women With Prosthetic Heart Valves(Imr Press, 2018) Akyol, A.; Yuman, M.; Sabin, M.; Simsek, H.; Akdag, S.; Gumrukcuoglu, H. A.; Tuncer, M.Introduction: Cardiac disease in maternity is a great problem particularly in developing countries. Pregnant patients with prosthetic heart valves (PHV) may suffer therapeutic difficulty, as the need for anticoagulation is fraught with risk of hemorrhagic or thromboembolic complications and structural valve deterioration. The present study aimed to evaluate the maternal, fetal outcome, and anticoagulant management in pregnant women with PHV. Materials and Methods: This study is prospective observational research. The medical archives of pregnant patients with PHV from September 2010 to January 2015 were scanned. Data collected from Yuzuncu Yil University Hospital Cardiology clinics archives included demographic characteristics, anticoagulant, presence or absence of obstructive or non-obstructive thrombus, and maternal-fetal outcome. Results: The authors evaluated the outcomes of 56 pregnant patients with PHV. The age at the time of pregnancy ranged between 19 and 37 (mean 28.7 +/- 8.4) years. Most common preferred anticoagulation therapy was heparin during the first trimester, followed by oral anticoagulation up to the 36th week, with subsequent replacement by heparin until delivery. Most common encountered complication was preterm birth. Death occurred in one patient due to obstructive valve thrombosis. Conclusion: Ideal PHV is not accessible for women during childbearing age. The risk of adverse event during pregnancy depends on valve position, symptoms, valve type, cardiac function, and functional capacity in patients with PHV. The active collaboration among an obstetrician, a cardiologist, and a cardiothoracic surgeon is required for optimal outcome patient with PHV.Article A New Echocardiographic Parameter of Arterial Stiffness in End-Stage Renal Disease(Urban & Vogel, 2014) Sahin, M.; Simsek, H.; Akyol, A.; Akdag, S.; Yaman, M.; Aydin, C.; Gumrukcuoglu, H. A.Background. Cardiovascular disease is the leading cause of death among patients with end-stage renal disease (ESRD). Arterial stiffness is an independent predictive parameter of overall and cardiovascular mortality in these patients. However, the defined procedures for the measurement of arterial stiffness are time consuming and not practical in daily practice. Methods. The study population included 50 patients with ESRD who were treated with hemodialysis (HD; n=23) or peritoneal dialysis (PD; n=27) and 70 age-and sex-matched control subjects. Aortofemoral pulse wave velocity (PWV), carotid intima-media thickness (CIMT), and color M-mode propagation velocity of the descending aorta (aortic propagation velocity, APV) were measured. Results. Compared to the control group, the patients with ESRD had significantly lower APV (46.4 +/- 12.4 vs. 58.5 +/- 8.5, p<0.01) and higher PWV (10.5 +/- 2.5 vs. 9.2 +/- 1.2, p<0.01) and CIMT (0.66 +/- 0.15 vs. 0.43 +/- 0.06, p<0.01) measurements. There were significant correlations between APV and CIMT (r=-0.769, p<0.001), APV and PWV (r=-0.682, p<0.001), and PWV and CIMT (r=0.564, p<0.001). There were no significant differences in APV and PWV between the PD and HD patients. Conclusion. Arterial stiffness is an important indicator of atherosclerosis and arterial aging in patients with ESRD. The measurement of APV is an easy and practical new echocardiographic method and may be used to identify arterial stiffness in these patients.Article A Novel Echocardiographic Method as an Indicator of Endothelial Dysfunction in Patients With Coronary Slow Flow(verduci Publisher, 2013) Simsek, H.; Sahin, M.; Gunes, Y.; Akdag, S.; Akil, M. A.; Akyol, A.; Yaman, M.BACKGROUND: To improve clinical outcomes, noninvasive imaging modalities have been proposed to measure and monitor atherosclerosis. Endothelial dysfunction is considered the first stage in the development of atherosclerosis. Brachial artery flow-mediated dilatation (FMD) has been impaired in patients with coronary slow flow (CSF). Recently, color M-mode derived propagation velocity of descending thoracic aorta (aortic propagation velocity-AVP) was shown to be an ultrasonographic marker for atherosclerosis. AIM: To assess endothelial function in patients with CSF and the correlation of AVP with FMD. MATERIALS AND METHODS: FMD and AVP were measured in 90 patients with CSF and 39 patients having normal coronary arteries (NCA) detected by coronary angiography. RESULTS: Compared to patients with normal coronary arteries patients having CSF had significantly lower AVP (39.1 +/- 8.4 vs. 53.7 +/- 12.7 cm/s, p < 0.001) and FMD (5.6 +/- 3.2 vs. 17.6 +/- 4.4 %, p < 0.001) measurements. There were significant correlations between AVP and FMD (r = 0.524, p < 0.001). CONCLUSIONS: Transthoracic echocardio-graphic determination of color M-mode propagation velocity of descending aorta is a simple practical method and correlates well with coronary slow flow and brachial endothelial function.Conference Object A Novel Echocardiographic Method for Assessing Arterial Stiffness in Obstructive Sleep Apnea Syndrome(Oxford Univ Press, 2015) Akdag, S.; Akyol, A.; Cakmak, H. A.; Gunbatar, H.; Asker, M.; Babat, N.; Gumrukcuoglu, H. A.Article Platelet-To Ratio May Predict the Severity of Calcific Aortic Stenosis(International Scientific Literature Inc., 2015) Akdag, S.; Akyol, A.; Asker, M.; Duz, R.; Gumrukcuoglu, H.A.Background: Platelet-to-lymphocyte ratio (PLR) is an emerging inflammatory indicator which is closely associated with adverse cardiovascular events. Therefore, we aimed to investigate the relationship between PLR and the severity of calcific aortic stenosis (AS). Material/Methods: The study was designed as a retrospective study. A total of 86 consecutive patients with calcific AS were divided into two groups as mild-to-moderate AS and severe AS according to the transaortic mean pressure gradient. PLR levels were calculated from the complete blood count (CBC). Results: Platelet to lymphocyte ratio was significantly higher in severe and mild-to-moderate AS groups when compared to the control subjects (151±31.2, p<0.001, 138±28.8 vs. 126±26.5, p=0.008, respectively). In the subgroup analysis of AS patients, PLR was found to be higher in the severe AS group compared to mild-to-moderate group (p<0.001). A significant correlation was found between PLR and transaortic mean pressure gradient in patients with AS (r=0.421, p<0.001). Conclusions: Our study results demonstrated that increased PLR correlates with the severity of calcific AS. © Med Sci Monit, 2015.Article A Rare Cause of Myocardial Infarction: Blunt Chest Trauma(Yuzuncu Yil Universitesi Tip Fakultesi, 2015) Kul, Ş.; Akyol, A.; Aşker, M.; Sahin, M.; Kucukdagli, O.T.; Uyarel, H.Blunt chest trauma is a rare cause of myocardial infarction. If the diagnosis is delayed, serious complications may occur. To prevent them, electrocardiography should be performed to all patients with chest pain after blunt chest trauma. In the event of myocardial infarction, coronary angiography should be performed as soon as possible and appropriate management interpreted according to clinical situation. © 2015, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.Article Two Markers in Predicting the Cardiovascular Events in Patients With Polycystic Ovary Syndrome: Increased P-Wave and Qt Dispersion(verduci Publisher, 2015) Akdag, S.; Cim, N.; Yildizhan, R.; Akyol, A.; Ozturk, F.; Babat, N.OBJECTIVE: Polycystic ovary syndrome (PCOS) is a prevalent disease with many potential long-term cardiovascular risks. P-wave dispersion (Pdis) and QT dispersion (QTdis) have been shown to be noninvasive electrocardiographic predictors for development of cardiac arrhythmias. In this study we aimed to search Pdis and QTdis parameters in patients with PCOS. PATIENTS AND METHODS: The study included 82 patients with PCOS and 74 age-and sex-matched healthy controls. Baseline 12-lead electrocardiographic and transthoracic echocardiographic measurements were evaluated. P-wave maximum duration (Pmax), P-wave minimum duration (Pmin), Pdis, QT interval, heart rate-corrected QT dispersion and QTdis were calculated by two cardiologists. RESULTS: Patients wirh PCOS had significantly higher QT dispersion (49.5 +/- 14.1 vs. 37.9 +/- 12.6 ms, p < 0.001), and P wave dispersion (54.2 +/- 11.4 vs. 45.9 +/- 10.1 ms, p < 0.001) than the controls. Serum testosterone and estradiol levels was correlated with the Pdis (r = 0.677, p < 0.001 and r = 0.415, p < 0.001 respectively) and QTdis (r = 0.326, p < 0.001 and r = 0.321, p < 0.001 respectively). CONCLUSIONS: Pdis and QTdis are simple and useful electrocardiographic markers which may be used in the prediction of the risk of adverse cardiovascular events in PCOS patients.