Browsing by Author "Alpaslan, N.Z."
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Article Evaluation of the Effects of Ab0 Blood Types on the Severity of Peri-Implant Diseases(Yuzuncu Yil Universitesi Tip Fakultesi, 2023) Onder, Y.B.; Alpaslan, N.Z.Peri-implant diseases are inflammatory conditions with a complex etiology including host-related risk factors and genetic traits which may affect the soft and hard gum tissues around dental implants. The aim of this study was to evaluate the effects of blood types on the severity of peri-implant diseases. A total of 77 dental implants of 39 patient s with periimplant diseases were included. Demographic data of the patients such as age, sex, frequency of tooth brushing and interdental cleaning and blood types were recorded. Clinical variables such as probing depth (PD), gingival index (GI), and plaque index (PI) and radiographic bone loss level were also noted. Dental implants were divided into two groups as Group 1 (n=19) including those diagnosed with peri-implant mucositis and Group 2 (n=20) including those diagnosed with peri-implantitis. The PD and GI scores and radiographic bone loss level were significantly higher in Group 2 than Group 1 (p<0.005). The frequency of tooth brushing was significantly higher in Group 1 than Group 2 (p=0.002). There was no significant difference in the distribution AB0 blood types between the groups (p>0.05). However, the majority of the patients had A Rh (Rhesus factor) (+) blood type in Group 1 and 0 Rh (+) blood type in Group 2. In conclusion, the blood types have no significant effect on the severity of peri-implant diseases. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.Article Investigation of Cyto-Toxicity of an Innovative Biofactor Mta Product in Different Human Cells: a Pilot Study(Termedia Publishing House Ltd., 2023) Akyol, G.D.; Kolcu, M.I.B.; Alpaslan, N.Z.; Taşpınar, F.; Mızrak, R.Y.; Tunç, S.K.; İnanç, B.Introduction: Mineral trioxide aggregate (MTA) is one of the most popular and convenient material among current endodontic materials. In addition to MTA advantages, there are also features that need to be improved. Color stability and consistency are notorious concerns in MTA, and materials need improvement regarding theses aspects. There are companies, which work on these contents. Objectives: The aim of this study was to investigate the cyto-toxicity of Biodentine, Angelus MTA, BIOfactor MTA on 3T3L-1 fibroblast, and Saos-2 osteosarcoma cell lines with different dilution of all products. Material and methods: 3T3-1 fibroblast was applied to stimulate pulp cells in cell viability test. In order to generate an osteoblastic cell-like model, only Saos-2 cells were used. MTT test was utilized to measure cell cytotoxicity in different dilution of all MTA products. SPSS package program was applied to perform Kruskal-Wallis, one-way ANOVA and two-way ANOVA tests. Results: According to results, while Biodentine, Angelus MTA and BIOfactor MTA showed cyto-toxic effects in 1: 1 and 1: 2 dilutions, they were not cyto-toxic in 1: 4 and 1: 8 dilutions. Conclusions: MTA products have similar cyto-toxicity. BIOfactor MTA has a cyto-toxic effect as other similar products. © 2023 Polish Dental Association.