Browsing by Author "Anlar, O"

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Brucellosis Incidence in Subjects With Headache in Eastern Turkey
(Dr Dietrich Steinkopff verlag, 2004) Anlar, O; Tombul, T; Akdeniz, H; Kisli, M; Kocturk, F; Caksen, H
A Comparison of Heart Rate Variability in Patients With Multiple Sclerosis Undergoing Immunomodulating Therapy or No Such Treatment
(Elsevier, 2005) Tombul, T; Tuncer, M; Eryonucu, B; Anlar, O
Epileptic Seizures in Neurobrucellosis
(Elsevier, 2005) Tornbul, T; Anlar, O; Caksen, H; Akdeniz, H
Hemispheric Dominance of Interictal Epileptiform Discharges
(Lippincott Williams & Wilkins, 1999) Tombul, T; Anlar, O; Tanik, O
Hemostatic Markers and Platelet Aggregation Factors as Predictive Markers for Type of Stroke and Neurological Disability Following Cerebral Infarction
(Churchill Livingstone, 2005) Tombul, T; Atbas, C; Anlar, O
We investigated the plasma levels of D-dimer, fibrinogen, beta-thromboglobulin (BTG) and platelet factor-4 (PF-4), indices of the occurrence of platelet activation in vivo, to find out their role in pathophysiology of ischemic stroke and whether or not such a role has any effect on the disability and the prognosis of stroke patients. A total of 76 patients with AIS aged from 26 to 85 (32 men, 44 women) and 30 cases as controls with similar age (18 men, 12 women) were included in the study. The plasma levels of D-dimer, BTG and PF-4 were measured by ELISA method using a special commercial kit. The cases were allocated into two groups as non-embolic (NEI) and cardioembolic stroke (CEI). The D-dimer levels in 76% of 42 patients in NEI group (p < 0.05) and 85.2% of 34 patients in CEI group (p < 0.05) were outside the confidence interval (CI) defined for the control group. The levels of BTG were elevated in 81% of 42 cases with NEI (p < 0.05) and in 76% of 34 cases with CEI, with reference to Cl of control group. The levels of PF-4 were significantly increased in 86% of cases with NEI (p < 0.05) and in 88% of cases with CEI than controls (p < 0.05). It was observed that the cases with high Rankin scores had higher levels of D-dimer (p < 0.005), BTG (p < 0.01) and PF-4 (p < 0.01) than those with lower scores. There was a correlation between hemostatic markers, platelet activation and functional disability. D-dimer levels were an important marker that determined to degree of the activation of hemostatic system, especially in CEI subtype. The platelet aggregation had an important role in pathophysiology of ischemic stroke and this condition is significant in NEI subgroup and subjects with large infarcts and high disability scores. (c) 2005 Elsevier Ltd. All rights reserved.
Interferon-Beta Treatment in Multiple Sclerosis Patients Decreases the Number of Monocytes in Peripheral Blood
(John Wiley & Sons Ltd, 2003) Anlar, O; Tombul, T; Ozbek, H; Dilek, L
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, characterized by the presence of sclerotic lesions throughout the brain. During clinical activity, monocytes activation markers such as Interleukin 1 and tumor necrosis factor-alpha (TNF-alpha) increase. The effect of interferon beta (IFN-beta) in reducing exacerbation rate and in slowing sustained worsening of disability has been shown in MS. The aim of this study was to determine levels of monocytes percentage in peripheral blood of MS patients receiving IFN-beta. We carried out this study in two groups of MS patients and a group of healthy subjects. First (study) group consisted of 13 patients treated by INF-beta. The control groups consisted of a) 14 MS patients group with no treatment by INF- beta and b) 20 healthy subjects. We counted the percentage of monocytes in the study group before and after one year of treatment by IFN- beta and in the control groups patients in the same period. At the end of one year, there was a significant reduction in the percentage of monocytes in peripheral blood of MS patients treated by interferon.
Mutism as a Complication of Total Intravenous Anesthesia by Propofol -: Reply
(Lippincott Williams & Wilkins, 2003) Kati, I; Demirel, CB; Anlar, O; Hüseyinoglu, UA; Silay, E; Elcicek, K; Elcicek, K.
Peripheral Nervous System Involvement in Patients With Beheet's Disease
(Elsevier, 2005) Anlar, O; Tombul, T; Akdeniz, N; Sayin, R; Calka, O; Metin, A
Report of Five Children With Guillain-Barre Syndrome Following a Nationwide Oral Polio Vaccine Campaign in Turkey
(Neurol Soc india, 2003) Anlar, O; Tombul, T; Arslan, S; Akdeniz, H; Caksen, H; Gundem, A; Akbayram, S
Five children with Guillain-Barre syndrome (GBS), following a national oral polio vaccination campaign to eradicate disease, are reported. Clinical examination, cerebrospinal fluid and electromyographic findings conformed to the classical description of GBS. Four of them received therapeutic dose of intravenous immunoglobulin G. Two children succumbed to the disease. It was observed that the number of cases of,GBS in children increased during the period of the oral polio vaccination campaign in Turkey, suggesting a causal relationship.
Seasonal and Environmental Temperature Variation in the Occurrence of Ischemic Strokes and Intracerebral Hemorrhages in a Turkish Adult Population
(Taylor & Francis Ltd, 2002) Anlar, O; Tombul, T; Unal, O; Kayan, M
Seasonal and weather influence on the incidence of cerebrovascular disease has been reported previously. The aim of this retrospective study was to determine whether the time of onset of ischemic strokes (IS) and intracerebral hemorrhages (ICH) were associated with the environmental temperature or the time, as a month or season, in our region. We analyzed the monthly and seasonal incidence of stroke between 1997 and 2001. Four hundred and fifty-one cases were admitted to our. clinic (IS; n = 288 and ICH; n = 163), and aged from 16 to 94 years. The study was carried out in province of Van in eastern Turkey. The present study demonstrated a peak occurrence of IS in August (n = 41). For ICH, we observed a peak occurrence in July (n = 23). The highest number of IS occurred in summer (n = 108), the most moderate amount in autumn (n = 81), and the least in spring (n = 38). The hemorrhagic events were hi-hest in summer (n = 58), most moderate in winter (n 61), and lowest in spring (n = 31) and autumn (n = 32). There Was a significantly greater incidence of IS and ICH during the summer than any other season in the province of Van, Turkey. This may reflect the role of weather temperature in the development of stroke and allow us to take preventive measures.
An Unusual Complication of Total Intravenous Anesthesia
(Lippincott Williams & Wilkins, 2003) Kati, I; Demirel, CB; Anlar, O; Hüseyinoglu, UA; Silay, E; Elcicek, K
We report a case of mutism secondary to total IV anesthesia with propofol, as an unusual complication that we have not found in the literature. Pulse oximetry may produce skin damage after the administration of photosensitizing chemotherapeutic drugs. Surgery must often be performed in near darkness during photodynamic therapy. Limiting the duration of pulse oximetry and rotating sites allowed successful use of pulse oximetry in a long anesthetic during which verteporphin was administered.
Visual Evoked Potential Findings in Behcet's Disease Without Neurological Manifestations
(Taylor & Francis Ltd, 2006) Anlar, O; Akdeniz, N; Tombul, T; Calka, O; Bilgili, SG
Behcet's disease (BD) is a chronic, recurrent multisystem inflammatory disorder firstly described by Turkish dermatologist Dr. Hulusi Beh et in 1937. The classic triad consists of recurrent oral and genital ulcerations and uveitis. The article presents the value of visual evoked potential findings of a series of 44 patients with BD without neurological manifestations seen at the Medical Hospital in Neurology and Dermatology clinics over the past 8 years. The mean latency value of positive peak P100 in BD patients was significantly delayed compared to that of control subjects ( patients's mean: 105.6 ms in right eye and 107.7 ms in left eye; control subject's mean: 101.4 ms in right eye and 101.7 ms in left eye).
Visual Evoked Potentials in Multiple Sclerosis Before and After Two Years of Interferon Therapy
(Taylor & Francis Ltd, 2003) Anlar, O; Kisli, M; Tombul, T; Ozbek, H
Magnetic resonance imaging (MRI) is important in the diagnosis of and follow-up for the treatment of multiple sclerosis (MS); evoked potentials may be important if MRI is normal or cannot be performed. We assessed serial visual evoked potentials (VEPs) and cranial MRI in a group of clinically relapsing-remitting multiple sclerosis (N = 15) treated with interferon beta-lb (INFB-1b) and in normal subjects (N = 15). The investigations were done I week before INFB-lb therapy, 1 year later (N = 15), and 2 years later (N = 10). VEPs were abnormal in most of the patients; MRIs were abnormal in all patients. We used P100 latency as an electrophysiological index for the progress of illness. There were significant differences in VEPs between the beginning and ending of the interferon treatment. We concluded that VEPs would be a reliable index for following up the progress of MS under interferon therapy.