Browsing by Author "Ari, Hasan Huseyin"

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Comparative Effects of Intra-Articular Administration of Vitamin C, Vitamin D, and Hyaluronic Acid in an Experimental Osteoarthritis Model in Rats
(Universidade Federal de Minas Gerais, 2025) Sancak, Tunahan; Yıldız, Ferit; Gürbüz, H. O.; Özmen, V.; Ari, Hasan Huseyin; Alkan, Ismail
Osteoarthritis (OA) is a chronic disease characterized by inflammation or cartilage deterioration in joints, leading to debilitating, movement-associated pain and degenerative changes in joint cartilage, bone, and other surrounding tissues, caused by factors such as joint injury, aging, obesity, and heredity. Various agents are used in OA treatment. In this study, hyaluronic acid, vitamin C and vitamin D were used in different combinations. A total of 32 rats were used in the study. After osteoarthritis was experimentally induced in the rats under general anesthesia, they were randomly divided into eight groups. Then, the preparations were administered intra-articularly as a single dose according to the groups. The study was terminated after 21 days. The tissues collected post-study were examined histopathologically. According to the histopathological findings of the study, the preparations provided mild cartilage tissue regeneration when applied individually, moderate regeneration when used in pairs, and significant regeneration and new bone trabecula formation when used in a triple combination. © 2025 Elsevier B.V., All rights reserved.
Determination of Some Morphological Characteristics of the Kyrgyz Taigan Dog Breed
(Wiley, 2025) Ari, Hasan Huseyin; Tas, Abuzer; Sen, Ismail; Bayraktar, Metin; Garip, Mustafa; Begaliev, Aziz; Salykov, Ruslan
This study involved morphological measurements of the body and head of 77 male and female Kyrgyz Taigans aged 12-16, 24-30 and 36+ months (denoted as groups 1, 2 and 3, respectively). Length measurements (head, face and ear) were obtained using an electronic calliper; width measurements (head, face and pinna) and circumference measurements (head, neck, chest, waist and front and rear shins) were taken using a measuring tape; and height measurements (withers and rump) were obtained using a measuring stick. IBM SPSS 22 was used for statistical analysis, and descriptive statistics of the groups were obtained. Student's t-test was used for between-group comparisons (gender), ANOVA for multiple-group comparisons (age), and the Tukey test for post hoc analysis. The average measurements for face, ear, tail, head, neck, front and rear shins, body length, and height were compared, and significant differences (p < 0.05) were observed between the male and female dogs in the three groups. Significant differences in neck, waist and chest circumferences and chest width and depth were also observed (p < 0.05). The Kyrgyz Taigan is a medium-sized dog breed in terms of body weight, is long-headed (dolichocephalic), exhibits a rectangular body shape similar to other greyhound breeds, and has a rump and withers that are of similar heights. Compared with other greyhound breeds, the Kyrgyz Taigan has greater values for head length, withers and rump heights, chest circumference and chest depth.
Surgical Removal of Coenurus Cerebralis Cysts Located in the Brain of Sheep
(Taylor & Francis Ltd, 2024) Tas, Abuzer; Sen, Ismail; Hatipoglu, Fatih; Ari, Hasan Huseyin; Risvanli, Ali; Salykov, Ruslan; Kyzy, Aiperi Aitmyrza
Coenurosis caused by Coenurus cerebralis poses a significant economic threat to sheep. To date, no effective treatment has been identified for this parasitic infection once it has settled in the brain. This study aimed to investigate the surgical removal of C. cerebralis cysts from the brains of infected sheep. Twenty sheep were utilized in the experiment, and the animals underwent a 24-hour fasting period before the surgical procedure. Various biochemical parameters, including TP, ALP, BUN, AST, CK, LDH, RBC, WBC, Hb, and Hct, were measured in the animals both before and one month after the operation. Anesthesia was induced by administering 2.2 mg/kg IV ketamine hydrochloride, five minutes after the administration of 0.1 mg/kg IV xylazine hydrochloride. Following anesthesia, the trepanation site was determined through percussion. Subsequently, an incision was made in the skin, exposing the skull bone. The skull was opened using a scalpel through trepanation, and the cysts were carefully removed. The results demonstrated that the presented surgical technique effectively treated C. cerebralis cysts in the sheep's brains, restoring normal motor and metabolic functions. Given these outcomes, it is concluded that the proposed surgical technique holds promise for practical application in the field.