Browsing by Author "Arisoy, A."

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Clinical and Prognostic Features of Patients With Pandemic 2009 Influenza a (H1n1) Virus in the Intensive Care Unit
(Makerere Univ, Fac Med, 2011) Sertogullarindan, B.; Ozbay, B.; Gunini, H.; Sunnetcioglu, A.; Arisoy, A.; Bilgin, H. M.; Baran, A., I
Objective: To investigate the clinical and prognostic features of patients admitted to intensive care unit (ICU) with pandemic 2009 influenza A (H1N1) virus. Methods: Patients admitted to the intensive care unit for severe pneumonia associated with pandemic 2009 influenza A (H1N1) virus were evaluated. Results: The study included 20 patients with the mean age of 36 +/- 13. Of the 20 subjects, 17 (85%) had underlying conditions. Of the 20 patients, 11(55%) were discharged and 9 (45%) died. Cardinal symptoms were fever, myalgia, and hemoptysis with the rates of 85 %, 75 % and 45 %, respectively. All patients had pneumonic infiltrations in their chest roentgenograms. Main laboratory findings were lymphopenia, high creatin phosphokinase (CPK) and Lactate dehydrogenase (LDH) levels. All patients had positivity on real time reverse transcription-polymerase chain reaction (RT-PCR). None of the patients had pandemic 2009 influenza A (H1N1) virus vaccination. None of them had taken oseltamivir within 48 hours. Main reasons for mortality were cardiovascular complications and ventilatory associated pneumonia due to Acynetobacter baumannii. Conclusion: Early diagnosis and antiviral treatment in these cases seem to be the best approach to avoid serious illness. Special attention should be given to patients having underlying conditions such as cardiovascular and pulmonary diseases and pregnancy.
The Correlation Between Red Blood Cell Distribution Width Levels With the Severity of Obstructive Sleep Apnea and Carotid Intima Media Thickness
(International Scientific Literature Inc., 2014) Gunbatar, H.; Sertogullarindan, B.; Ekin, S.; Akdag, S.; Arisoy, A.; Sayhan, H.
Background: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive collapse of the upper airway during sleep. Red blood cell distribution width (RDW) increases platelet activation and has been reported as an independent predictor of adverse outcomes in the general population and is believed to be associated with cardiovascular morbidity and mortality. We evaluated RDW, mean platelet volume (MPV), and platelet distribution width (PDW) as a severity index in OSAS and the relationship between carotid intima media thickness and pulmonary hypertension.; Material/Methods: The study population consisted of 99 patients who were admitted to the sleep laboratory. Based on the apneahypopnea index, patients were grouped into 3 OSAS severity categories. Morning blood samples were withdrawn from patients after a 12-hour fasting period. MPV, PDW, and RDW were measured in a blood sample. Bilateral common carotid arteries of the patients were scanned.; Results: Ninety-nine patients – 73 with OSAS and 26 simple snoring control cases – were included. Mean values of MPV, PDW, and RDW were similar in patients compared to simple snoring subjects in the control group (p=0.162, p=0.656, p=0.091). RDW showed an inverse correlation with mean desaturation and lowest desaturation (p<0.01). Body mass index, apnea-hypopnea index, pulmonary artery pressure, and desaturation time under 90% were positively correlated with RDW (p<0.05). MPV, PDW, and carotid intima media thickness had no correlation with any other parameters.; Conclusions: The study showed a positive relationship between RDW and the apnea-hypopnea index and systolic pulmonary hypertension in patients with OSAS. © Med Sci Monit, 2014.
Does Hypoxia Only Importan for Fatty Liver in Osa Patients
(Amer Thoracic Soc, 2016) Sertogullarindan, B.; Bulut, D.; Gunbatar, H.; Sunnetcioglu, A.; Ekin, S.; Arisoy, A.
Is İt İn Our Genes That We're Going To Have Pulmonary Embolism
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Uney, İ.H.; Arisoy, A.; Sunnetcioglu, A.; Mermit Çilingir, B.; Yıldız, H.; Gunbatar, H.; Asker, S.
Pulmonary thromboembolism is a disease with high mortality and morbidity, which can be recurrent, difficult to diagnose, yet preventable and treatable. In this study, our aim was to evaluate comorbidities, risk factors, laboratory results, and clinical scoring in patients diagnosed with pulmonary embolis m. Our primary goal was to detect genetic mutations in cases of pulmonary embolism with acquired risk factors. Our study is a prospective study that includes clinical information, laboratory tests, Wells scoring, admission, and the prospective history of 60 patients with no previous history of venous thromboembolism (VTE) and no history of anticoagulation use. These patients were admitted to the chest diseases outpatient clinic, emergency department, or hospitalized for another reason and diagnosed with pul monary thromboembolism. The mean age of the patients was 59.9 ± 18.7 years. The most common presenting complaints were shortness of b reath and sharp chest pain. Nearly half of the patients had at least one comorbid disease. There was at least one genetic/congenital risk factor in all cases, and at least two risk factors were present in more than half of the cases. The most common mutati ons were plasminogen activator inhibitor type 1 (PAI-1) and Methylenetetrahydrofolate Reductase (MTHFR) heterozygote mutations. Pulmonary embolism continues to be a more prevalent disease with increasing age and associated risk factors. Since there is at least one acquired risk factor in all of our cases, we believe that almost every patient may have an acquired risk factor if the history is thoroughly investigated. We also believe that genetic or thrombophilic conditions may be detected in almost all cases diagnosed with pulmonary embolism. It has been concluded that immobilization and obesity are the most common preventable risk factors associated with VTE. © 2024, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Utility of Computed Tomography in Assessment of Pulmonary Hypertension Secondary To Biomass Smoke Exposure
(International Scientific Literature Inc., 2014) Sertogullarindan, B.; Bora, A.; Yavuz, A.; Ekin, S.; Gunbatar, H.; Arisoy, A.; Ozbay, B.
Background: The aim of this study was to investigate the feasibility of main pulmonary artery diameter quantification by thoracic computerized tomography (CT) in the diagnosis of pulmonary hypertension seconder to biomass smoke exposure. Material/Methods: One hundred and four women subjects with biomass smoke exposure and 20 healthy women subjects were enrolled in the prospective study. The correlation between echocardiographic estimation of systolic pulmonary artery pressure and the main pulmonary artery diameter of the cases were studied. Results: The main pulmonary artery diameter was 26.9±5.1 in the control subjects and 37.1±6.4 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). The systolic pulmonary artery pressure was 22.7±12.4 in the control subjects and 57.3±22 in subjects with biomass smoke exposure. This difference was statistically significant (p<0.001). Systolic pulmonary artery pressure was significantly correlated with the main pulmonary artery diameter (r=0.614, p<0.01). A receiver operating characteristic (ROC) curve analysis showed that a value of 29 mm of the main pulmonary artery diameter differentiated between pulmonary hypertension and non-pulmonary hypertension patients. The sensitivity of the measurement to diagnose pulmonary hypertension was 91% and specificity was 80%. Conclusions: Our results indicate that main pulmonary artery diameter measurements by SCT may suggest presence of pulmonary hypertension in biomass smoke exposed women. © Med Sci Monit.