Browsing by Author "Arslan, B."

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1800 Mhz Radio-Frequency Electromagnetic Radiation Induces Oxidative Stress in Rat Liver, Kidney and Brain Tissues
(Yuzuncu Yil Universitesi Tip Fakultesi, 2018) Berköz, M.; Arslan, B.; Yıldırım, M.; Aras, N.; Yalın, S.; Çömelekoğlu, Ü.
Radio-frequency electromagnetic radiation (RF-EMR) represents one of the environmental factor that influence animal organism to stress. In this study we determined the oxidative stress parameters from rat liver, kidney and brain tissues that were exposed to chronic 1800 MHz RF-EMR. Our study was designed in 3 groups as 9 animals in each group. These are; control, sham and RF-EMR exposed group. The control group was not exposed to any procedure; sham group was housed in the same room under the same conditions with equal time period, except that the generator was turned off. RF-EMR exposed group was subjected to 1800 MHz RF-EMR emitted from the signal generator for 2 h per day for eight weeks. All animals that completed the experimental period were sacrificed and liver, kidney and brain tissues of all rats were isolated for analyzing malondialdehyde (MDA), nitric oxide (NO) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activities. Liver, kidney and brain MDA and NO levels were higher and GSH level and SOD and catalase activities were significantly lower in RF-exposed group than control and sham groups (p<0.001). No significant difference was observed in terms of tissue MDA, GSH and NO levels and SOD and catalase activities between control and sham groups in each tissue. The results of our study shows that RF-EMR may act as an environmental stressor and cause oxidative and nitrosative damage in liver, kidney and brain tissues. © 2018, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Epidemiological Evaluation of Patients Diagnosed with Lymphoma and the Retrospective Evaluation of the Endocrinological Parameters as Late Side Effect of the Patients without the Treatment
(Yuzuncu Yil Universitesi Tip Fakultesi, 2025) Arslan, B.; Öner, A.F.; Erseckin, A.; Karaman, K.
In this study, it was aimed to retrospectively evaluate the epidemiological characteristics and long-term side effects related to hormon and bone metabolism in the follow-up of lymphoma patients between the ages of 0-18 years. 98 patients who were diagnosed with HL and NHL between 2007-2020 in the Van Yuzuncuyil University Pediatric Hematology Clinic were retrospectively scanned from the hospital database. The mean age of children was 96 months. It was determined that 74 (75.5%) children were boys and 24 (24.5%) were girls. No statistically significant difference was found in terms of age at diagnosis, and gender distribution of children diagnosed with HL and NHL (p=0.347, p=0.095, respectively). 25 OH vit-D deficiency was found in 21 (84%) children with a diagnosis of HL and 10 (71.4%) children with a diagnosis of NHL (p=0.187). Growth and developmental delay was found in 2 (2%) children with a diagnosis of HL. Early puberty was observed in 4 (4.1%) children, and delayed puberty was detected in 3 (5.5%) children. The median TSH, 25 OH vit-D levels and puberty findings were similar in NHL and HL group (p=0.241, p=0.399, p=0.505, respectively). Hypothyroidism was 5.1% before C hT-RT, it increased to 11.1% after ChT-RT. However, this difference was not statistically significant (p=0.241). We conclude that it is important to evaluate patients regularly in terms of endocrinological and metabolic side effects related to ChT and RT during the treatment process and long-term follow-up. © 2025, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Revisiting the Sphenoid Sinus Anatomy in Trisomy 21: A CT Study
(Lippincott Williams & Wilkins, 2025) Arslan, B.; Erdem, M.Z.; Yalınkılıç, A.; Karaaslanlı, A.; Beǧer, B.; Sönmez, B.; Koç, T.
OBJECTIVE: The aim of the study was to compare morphologic features of the sphenoid sinus (SS) in patients with trisomy 21 (T21) with a control group. METHODS: This retrospective study contained computed tomography images of 50 T21s and 60 controls. Of 50 T21 patients aged 11.38±4.21 years, 22 were females and 28 were males. Of 60 controls aged 11.25±4.61 years, 30 were females and 30 were males. The volume (SSV), surface area (SSA), width (SSW), thickness (SST), and height (SSH) of SS were measured. The shape of SS was noted. RESULTS: In T21s, median values for SSV, SSA, SSW, SST, and SSH were determined as 1.99 mm 3 , 1.52 mm 2 , 20.10 mm, 9.85 mm, and 13.60 mm, respectively. In controls, median values for SSV, SSA, SSW, SST, and SSH were determined as 9.55 mm 3 , 5.50 mm 2 , 30.44 mm, 19.67 mm, and 19.88 mm, respectively. T21s had statistically smaller SSV, SSA, SSW, SST, and SSH compared with controls ( P <0.001). Four types related to SS shape were observed in T21s (conchal: 42%, presellar: 30%, sellar: 24%, and postsellar: 4%) and controls (presellar: 33.3%, sellar: 31.7%, postsellar: 30%, and conchal: 5%). Thus, SS shape was affected by T21s ( P <0.001). CONCLUSIONS: Patients with T21 had statistically smaller SSV (about 79%), SSA (about 72%), SSW (about 34%), SST (about 50%), and SSH (about 32%) compared with controls. The most common pneumatization pattern in T21s was the conchal type. © © 2025 by Mutaz B. Habal, MD.