Browsing by Author "Arslan, S."

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The Assessment of Anti-Cancer Potential of Macroalgae Alkaloid Tyramine on Colon Cancer Cell Lines
(Wiley, 2023) Babat, C. Fidan; Yilmaz, C.; Abdelsalam, A. H.; Arslan, S.
Budd-Chiari Syndrome in a Patient Heterozygous for Both Factor V Leiden and the G20210a Mutation on the Prothrombin Gene
(Schattauer GmbH, 1999) Oner, A.F.; Arslan, S.; Caksen, H.; Ceylan, A.
A Case of Bartter’s Syndrome Associated With Nephrocalcinosis Presenting With Tetany
(2004) Ataş, B.; Çaksen, H.; Tuncer, O.; Kirimi, E.; Arslan, S.; Erol, M.; Yuca, S.A.
A 10-year-old boy was admitted to hospital with a 3 month history of intermittent spasms of the wrists and ankles, and twitching of the eyelids. He also had polyuria, polydipsia, nocturnal enuresis, fatigue and constipation since he was a toddler. Physical examination revealed normal blood pressure, myokymia on the right eyelid and bilateral carpopedal spasms. Laboratory investigation revealed hypocalcemia, hypokalemia, increased plasma renin and aldosterone, hypercalciuria, metabolic alkalosis, and bilateral medullary nephrocalcinosis. Cranial computed tomography was normal. Based on the clinical and laboratory findings he was diagnosed as having Bartter’s syndrome, which is characterized by hypochloremia, hypokalaemia and metabolic alkalosis associated with potassium renal leakage, with normal blood pressure despite increased plasma renin activity. It is well known that tetany is not uncommon in the neonatal form of Bartter’s syndrome and nephrocalcinosis is usually not present in the classic form. Interestingly, our patient had both the clinical manifestations of the neonatal form and of the classic form of Bartter’s syndrome. In conclusion, we would like to emphasize that both the clinical manifestations of neonatal and classic forms of Bartter’s syndrome (as an overlapping syndrome) might be seen in children and that Bartter’s syndrome should also be considered in children with tetany as in our case. © 2004, IOS Press. All rights reserved.
Childhood Brucellosis: a Retrospective Study of 103 Cases
(1999) Arslan, S.; Oner, A.F.; Caksen, H.; Cesur, Y.; Ceylan, A.; Atas, B.; Abuhandan, M.
In this study, the clinical and laboratory findings of 103 patients who were followed in our hospital with the diagnosis of brucellosis in our hospital were reviewed retrospectively. Our purpose was to determine the initial drug combination used in its treatment, and to stress the importance of this disease as a public health problem in Turkey, particularly in the Van region. Of the 103 patients, 52 were female and 51 were male. The patients' ages ranged from 20 months to 16 years (mean 8.31 ± 3.58 years). The most observed symptoms were fever (55.3%), arthralgia (53.3%), malaise (41.7%) and loss of appetite (30%). The most observed signs were hepatosplenomegaly (22.5%), hepatomegaly (20.5%), arthritis (17.4%) and splenomegaly (15.5%). Anemia was present in 18 (17.4%) patients, leukopenia in eight (7.7%), and leukocytosis in 15 (14.5%). Erythrocyte sedimentation rate was studied in 84 (81.5%) patients; it was higher than 20 mm/hour in 52 (61.9%) patients. Liver function tests were studied in 55 (53.3%) patients; AST (aspartate aminotransferase) and ALT (alanine amino transferase) were abnormal in 31 (56.3%) and in 55 (53.3%) patients respectively. Brucella agglutination test was 1/160 or higher in all patients; it was ≥1/320 in most patients (83.5%). In the treatment, 12 types of drug combination used, primarily rifampin + co- trimoxazole, rifampin + tetracycline and streptomycin + co-trimoxazole. All except seven patients were successfully treated with the initial drug combination used. For the these seven patients, the initial drugs were changed for different drug regimens. There was no difference between the drug combination and recovery ratio (p>0.05). No relaps were noted.
Choledochus Cyst: a Case Report
(2011) Kaya, A.; Aktar, F.; Açikgöz, M.; Üstyol, L.; Başaranoǧlu, M.; Arslan, S.
The etiologies of choledochus cysts are not exactly known. Its classic triads are abdominal pain, mass in abdominal area and icter. A 2-year-old girl was brought in with temperature, vomiting and abdominal pain complaints. In her physical examination, there was no sensitivity, defense and rebound in the abdomen. There was also no icter in her body. In the laboratory examination aspartate transaminase and alanine aminotransferase were slightly high, gama-glutamyl transferase and alkaline phosphatase also significantly high. Her abdomen ultrasonography showed a dimensionally cystic dilatation with dimensions of 2x1,5 cm and cholecytitis was seen in choledochus proximals. In abdomen computerized tomography a dimensionally 13 mm cystic structure was observed in choledochus distal terminus adjacency associated with choledochus. Our case was orientated to pediatric surgery in terms of follow-up and therapy.
Determination of Underlying Causes in Asymptomatic, Earlystage Renal Diseases by Dipstick Test
(Medical Association of Zenica-Doboj Canton, 2013) Okur, M.; Arslan, S.; Guven, A.S.; Temel, H.; Bektas, M.S.; Ustyol, L.
Aim To prevent possible chronic kidney diseases in healthy school- age children by screening for hematuria and proteinuria using a urine strip. Methods The incidence of hematuria and proteinuria was determined in 1848 healthy school-age children aged 7 to 14 years by urine screening in the eastern region of Turkey in 2008. Cases with persistent hematuria and/or proteinuria were referred to a pediatric nephrologist, and further examinations were carried out. Results Isolated hematuria, isolated proteinuria, and combined hematuria-proteinuria were found in 92 (4.9%), 16 (0.8%) and 10 (0.5%) patients, respectively. In addition, 11.9% (11/92) of cases of isolated hematuria and 40% (4/10) of cases of combined hematuria- proteinuria were observed to have persisted. Persistent hematuria and persistent hematuria-proteinuria were found in 11 (0.5%) and 4 (0.2%) patients, respectively. In these cases, underlying causes were found: renal stone disease, hypercalciuria, urinary tract infection, vesicoureteral relux, atrophic kidney, and IgA nephropathy. Conclusion According to this study, cases with persistent hematuria should be examined especially in terms of renal stones, hypercalciuria, and urinary tract infection.
The Effect of Triclabendazole (Fasinex) in Children With Fasciolosis
(1998) Yilmaz, H.; Oner, A.F.; Akdeniz, H.; Arslan, S.
Three children infected with Fasciola hepatica (FH) were treated with triclabendazole (TCZ; Fasinex). In the first two patients, firstly, albendazole (Andazole) was administered, but did not stop the excretion of FH eggs. To these two patients, TCZ was administered in a single oral dose of 10 mg/kg postprandially. Two month later, very few eggs were found in stool samples. So, the same dose of triclabendazole was secondly given to the patients. After this therapy. FH eggs have not been found in the repeated stool examinations for a follow up of one year. To the third patient, TCZ was administered in a single oral dose of 10 mg/kg together with food. This patient has remained free of complaints and stool samples were free from FH eggs for two months. In conclusion, TCZ may be used as a treatment of choice for human fasciolosis both in adults, and children.
Fleece Characteristics of Karakas, Norduz, Ile De France X Akkaraman Cross Bred Sheep
(indian veterinary Journal, 2007) Karakus, K.; Aygun, T.; Arslan, S.
Most of the native sheep breeds in Turkey have low meat and wool yields. The fat tailed Karakas and Norduz sheep, subtype of the Akkaraman sheep breed, are favourably characterized by their adaptation to harsh environmental and feeding conditions. Karakas and Norduz sheep are found in Van provinces of Eastern Anatolia in Turkey. This study was aimed to compare some fleece characteristics of Karakas, Norduz, Ile de France x Akkaraman (G) and Ile de France x Akkaraman (G) x Karakas (F-1) sheep and to investigate the wool characteristics of Ile de France crosses with native sheep for utilization possibilities in traditional products (hand-made carpet and kilim).
A Girl Presenting With Intractable Seizure and Decreased Visual Acuity
(2012) Kocaoǧlu, C.; Akin, F.; Sert, A.; Çaksen, H.; Öner, V.; Kiliçaslan, C.; Arslan, S.
Neuronal ceroid lipofuscinoses are the most common neurodegenerative childhood-onset disorders characterized by autosomal recessive inheritance, epileptic seizures, progressive psychomotor deterioration, visual failure, and premature death. At least eleven subtypes of childhood-onset neuronal ceroid lipofuscinoses have been identified. The most common types are the infantile and classic juvenile forms. In this article, we present a 5-yearold girl with late infantile neuronal ceroid lipofuscinosis who presented with seizures and decreased visual acuity. She was healthy and her developmental milestones were normal until 3 years of age. At the age of 3-year-old, her intractable seizures started and decreased visual acuity was recognized. Based on the clinical findings and enzymatic test results, she was diagnosed as late-infantile ceroid lipofuscinosis.
High Altitude and Blood Pressure in Children
(2003) Arslan, S.; Arslan, N.; Soylu, A.; Akgün, C.; Tepebasili, I.; Türkmen, M.; Kavukçu, S.
We aimed to evaluate the blood pressure of children who had similar demographic characteristics but lived at different altitudes. Blood pressure of the children attending primary schools in Izmir (sea level: n = 425) and Van (altitude: 1725 m, n = 291) were measured by mercurial sphygmomanometer for this study. They were similar with respect to age, sex, weight, height, and BMI. Mean age of the children was 10.51 ± 0.87 years (range: 9 to 12 years), and 358 (50 percent) of them were female. Mean systolic blood pressure was significantly higher in the children living in Van than in the children living in Izmir (104.72 ± 11.2 vs. 97.96 ± 25.5 mmHg, respectively, p < .001). Similarly mean diastolic blood pressure was significantly higher in the children living in Van than in the children living in Izmir (63.98 ± 9.3 vs. 59.91 ± 10.0 mmHg, respectively, p < .001). When blood pressure was evaluated with regard to height percentile, the number of children with a blood pressure over 90 percentile were 19 (4.5 percent) and 48 (16.5 percent) for systolic blood pressure, and 25 (5.9 percent) and 37 (12.7 percent) for diastolic blood pressure among the children living in Izmir and Van, respectively (p < .001). Systolic and diastolic blood pressures were found to increase in parallel to the increase in body mass index in children living in Van (r = 0.358, p < .001 and r = 0.235, p < .001, respectively). However, blood pressures were not correlated to body mass index in children living in Izmir. A difference of 1700 m in altitude was associated with higher systolic and diastolic blood pressure levels in children with similar demographic characteristics, and at this altitude, body mass index and blood pressure showed a positive correlation. Copyright © 2004. All rights reserved.
Hyponatremic Dehydration: an Analysis of 78 Cases
(2001) Çaksen, H.; Odabaş, D.; Şar, A.; Çelebi, V.; Arslan, S.; Kuru, M.; Abuhandan, M.
Our purpose was to determine the frequency of convulsion in children with hyponatremic dehydration (HD). We also investigated whether or not there was a relationship between the severity of hyponatremia and the degrees of malnutrition in our region (Eastern Anatolia of Turkey) in where malnutrition is frequently observed. In this study, the clinical and laboratory findings of 78 patients with diarrhoea (acute, persistent or chronic diarrhoae) and HD were studied. When diarrhoea lasts longer than 2 and 4 weeks they were accepted as persistent and chronic diarrhoea, respectively. Patients were said to have HD if they had the clinical findings of dehydration associated with hyponatremia [Serum sodium (SNa) <130 mmol/L)]. Nutritional status of the children was assessed by the Gomez classification using weight for age; it was accepted as normal those were between 90%-110%, mild malnutrition 75%-89%, moderate malnutrition 60%-74% and severe malnutrition <60%. Of 78 patients, 40 were boys, 38 were girls. The age and weight of the patients ranged from 40 days to 36 months (8.94 ± 5.49 months) and from 2000 to 10300 g (5535.25 ± 1702.10 g) respectively. All patients except four had malnutrition; 15 (20.3%) had mild malnutrition, 30 (40.5%) had moderate malnutrition and 29 (39.2%) had severe malnutrition. Forty-seven patients had acute, 16 patients had persistent, and 15 patients had chronic diarrhoea. SNa levels were between 104 and 129 mmol/L (121.21 ± 6.12 mmol/L). There was not statistically a significant difference between SNa level and the degree of malnutrition, and SNa level and the types (acute, persistent or chronic) of diarrhoea (p > 0.05). Of 78 patients, 12 (15.3%) patients had convulsion, of whom eight had convulsion associated with fever. Convulsion was noted in nine (19.1%) and three (18.7%) patients with acute and persistent diarrhoea, respectively (p > 0.05). Also, we observed that when hyponatremia was severer, convulsions tended to be more occurring (p < 0.05). Five (6.4%) children died and all of them had severe malnutrition and septicemia. We determined that the frequency of convulsion in HD was 15.3% (12/78), and there was not a difference between the cases of acute, persistent and chronic diarrhoea for the frequency of convulsion. We also found a significant difference was not present between SNa level and the degree of malnutrition, and between SNa level and the types (acute, persistent or chronic) diarrhoea. However, we observed that when hyponatremia was severer, convulsions tended to be more occurring.
Implementation and Evaluation of an Efl Teacher Training Program for Non-Formal Education Settings
(Ankara University, 2020) Arslan, S.; Mirici, İ.H.; Öz, H.
This study aims to implement and evaluate a suggested in-service teacher training program for English language teachers in non-formal education institutions. In doing this, 2-week online training program was designed considering the professional needs of the teachers and implemented with a follow-up. Pre and posttests, self-assessment scales and lesson observations were utilized in order to compare teacher knowledge and behaviors before and after the training. In addition, those instruments, feedback forms were also received from the teachers in order to figure out their attitudes towards the implemented program. Findings from the study showed that the program had a significant impact on teacher knowledge and behaviors. Although the majority had a positive attitude towards the program, some teachers suggested that a face-to-face training program be held and that the length could be extended. © 2020, Ankara University. All rights reserved.
Multicystic Renal Dysplasia in a Child With Split Hand/Split Foot Malformation
(TIP ARASTIRMALARI DERNEGI, 2012) Akgün, C.; Akbayram, S.; Başaranoǧlu, M.; Aktar, F.; Temel, H.; Arslan, S.
Split hand/split foot malformation is a human developmental disorder characterized by missing central digits and other distal limb malformations. Multicystic renal dysplasia is the most common cause of an abdominal mass in the new born period and is the most common cystic malformation of the kidney in infancy. Here, we report a case of split hand/split foot malformation with a submucosed cleft palate and multicystic renal dysplasia in one-year old boy.
Myoglobinuric Renal Failure - Response
(Elsevier Science inc, 2004) Kirimi, E; Tuncer, O; Atas, B; Arslan, S; Ataş, B.; Arslan, S.
P Wave Duration and Dispersion in Patients With Hyperthyroidism and the Short-Term Effects of Antithyroid Treatment
(2009) Guntekin, U.; Gunes, Y.; Simsek, H.; Tuncer, M.; Arslan, S.
Background: Prolonged P wave duration and P wave dispersion (PWD) have been associated with an increased risk for atrial fibrillation (AF). Hyperthytodism is a frequent cause of atrial fibrillation (AF). Methods: Forty-two patients with newly diagnosed overt hyperthyroidism and 20 healthy people were enrolled in the study. Transthoracic echocardiography, 12 lead surface ECG and thyroid hormone levels were studied at the time of enrollment and after achievement of euthyroid state with propylthiouracil treatment. Results: Maximum P wave duration (Pmax) (97.4±14.6 vs. 84.2±9.5 msec, p<0.001), PWD (42.9±10.7 vs. 31.0±6.2 msec, p<0.001), deceleration (DT) (190.7±22.6 vs. 177.0±10.2 msec, p=0.013) and isovolumetric relaxation times (IVRT) (90.9±11.2 vs. 79.6±10.5 msec, p<0.001) were significantly higher in hyperthyroid patients compared to control group. Pmax and PWD were significantly correlated with the presence of hyperthyroidism. Pmax (97.4±14.6 to 84.3±8.6 msec, p<0,001) Pmin (54.1±8.6 to 48.1±8.5 msec, p=0.002), PWD (42.9±10.7 to 35.9±8.1 msec, p=0.002) and DT (190.7±22.6 to 185.5±18.3, p=0.036) were significantly decreased after achievement of euthyroid state in patients with hyperthyroidism. Diastolic dyfunction was seen in 5 patients at hyperthroid state but only in one patient at euthyroid state. Conclusions: Hyperthyroidism is associated with prolonged P wave duration and dispersion. Achievement of euthyroid state with propylthiouracil treatment results in shortening of P wave variables. Diastolic function may have a partial effect for the increased Pmax and PWD. Shortening of Pmax and PWD may be a marker for the prevention of AF with the anti-thyroid treatment.
Public Pedagogy Approach Towards Online Language Instruction: Use of Fandom With a Dialogic Perspective
(IGI Global, 2021) Arslan, S.
Thanks to the widespread use of social media among individuals, the new site for the public pedagogy can be based on 'fandom', which is strongly related to fan-related practices on websites, forums, pages, and channels. These venues are based on shared interests and enjoyment and are visited by thousands of people every day. Inspired by increasing popularity, fandom has been used in academic education for the last decade. In line with this, there is also a growing research interest in the use of fandom in foreign/second language teaching; however, this should be within a purposeful way to enrich the opportunities for online learning. Therefore, this chapter sets out to provide practical implications about the operationalization of fandom in online language instruction to promote interaction among learners, which is quite necessary, particularly in the time of school closures due to the pandemic. © 2021 by IGI Global. All rights reserved.
Report of a Girl With Vacterl Syndrome and Right Pulmonary Agenesis
(Medecine Et Hygiene, 2009) Avcu, S.; Akgun, C.; Temel, H.; Arslan, S.; Akbayram, S.; Unal, O.
Report of a girl with VACTERL syndrome and right pulmonary agenesis: VACTERL syndrome is a combination of vertebral anomalies (V), anal atresia (A), congenital heart defects (C), tracheo-esophageal fistula (T), esophageal atresia (E), abnormalities of kidneys (renal anomalies, R) and limbs (L). In the present patient right pulmonary agenesis is co-occurring with VACTERL syndrome. We report on this case because the association of right pulmonary agenesis and VACTERL syndrome is rare.
Rubella Seroprevalence in Adolescent Girls in the Eastern Region of Turkey
(2002) Çaksen, H.; Ceylan, A.; Ceylan, N.; Arslan, S.; Öner, A.F.; Kirimi, E.; Gölbasi, C.
The Screening of Hematuria and Proteinuria in School-Age Children
(Wiley-blackwell, 2011) Okur, M.; Arslan, S.; Guven, A. S.; Temel, H.; Bektas, Ms; Ustyol, L.
Serum Immunoglobulins and Immunoglobulin G Subclasses With Recurrent Wheezing
(The Indian Journal of Pediatrics, 2000) Öner, A.F.; Çaksen, H.; Çelik, A.; Cesur, Y.; Üner, A.; Arslan, S.
In this study serum immunoglobulins (Ig) and IgG subclasses were measured in 42 patients (ranging 9 month-6 year) with recurrent wheezing and in 37 healthy children determined the relationship between serum Igs and recurrent wheezing. Patients were divided into two groups according to the age [9 month-2 year (n: 15), and 2-6 year (n: 27)]. In the patients placed in 9-24 month age group, serum IgG4 level was found to be lower than controls (p<0.05). But there was not a significant difference in mean serum concentrations of total IgG, IgA, IgM, IgE, IgG1, IgG2 and IgG3 subclasses between the groups (P>0.05). In the 25 month-6 year age group the mean IgE level was increased compared to the control while IgG3 and IgG4 levels were decreased (p<0.05). On the other hand, in the 9-24 month age group there was no significant difference between the patients and controls for IgG subclasses deficiency (P>0.05). However, significant difference in IgG subclasses deficiency was present between the patients and controls in the 25 month-6 year group (P<0.001). In conclusion, our findings suggest that wheezing in childhood may be associated with low IgG3 and/or IgG4, and in older children high IgE level may be a part of pathogenetic mechanism in patients with recurrent wheezing.