Browsing by Author "Aslan, Lokman"

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Otolog Fibrin Yapıştırıcının Açık Yara Tedavisinde İyileşme Üzerine Etkisi: Deneysel Çalışma
(2001) Aslan, Lokman; Bakır, Bahtiyar; Karasu, Abdullah; Yüksel, Hayati; Gençcelep, Musa
Bu çalışmada; köpeklerde deneysel oluşturulan açık yaralarda otolog fibrin yapıştırıcısının iyileşme üzerine etkisi klinik ve histopatolojik olarak araştırıldı.Çalışmada, 14 adet sağlıklı melez köpek kullanıldı. Köpekler T şer hayvandan oluşan kontrol (K) ve otolog fibrin (D) gruplarına ayrıldı. Xylazin HCl ve Ketamin HCl ile gerçekleştirilen anesteziden sonra sağ veya sol göğüs çeperinde 4,5 cm çapında aseptik yaralar oluşturuldu. K grubuna serum fizyolojik, D grubuna aprotinin içermeyen otolog fibrin yapıştırıcı uygulandi-Klinik olarak her iki grup 21. güne kadar kabuk oluşumu, granülasyon doku gelişimi, epitelizasyon ilerlemesi ve enfeksiyon varlığı açısından incelendi. Morfolojik yönden, her iki gruptan sağlam ve yaralı dokuyu kapsayan örnekler alınarak, inflamasyon, fibroblast proliferasyonu, kollajen sentezi, granülasyon doku oluşumu ve epitelizasyon durumu incelenerek değerlendirildi. Sonuç olarak, otolog fibrin yapıştırıcı kullanımının kontrol grubuna göre yara iyileşme sürecini hızlandırdığı kanısına varıldı.
Papillary Cyst Adenogarcinoma in the Mammary Gland of a Van Cat
(indian veterinary Journal, 2006) Yuksel, Hayati; Yuksek, Nazmi; Aslan, Lokman; Ilhan, Fatima; altug, Nuri
Mammary tumours of dogs and cats are among the most commonly observed neoplastic changes after skin and lymphoid tissue tumours (Viste et al., 2002). The etiology of feline mammary tumours are not well identified, they are more commonly seen in female cats while being rare in the male (Bostock, 1986; Hahn and Adams 1997). Cat mammary tumours are mostly malignant upon microscopic examination, and are generally seen in cats of 10 years of age without showing any breed predisposition (MacEwen et al., 1984). In this report a papillary cystic adenocarcinoma that was observed in the mammary gland of a Van cat together with its histopathological and immunohistochemical findings is described.
Retinal Fiber Layer Thickness in Children With Thalessemia Major and Iron Deficiency Anemia
(Taylor & Francis inc, 2014) Aksoy, Adnan; Aslan, Lokman; Aslankurt, Murat; Eser, Ozlem; Garipardic, Mesut; Okumus, Seydi; Kaya, Gul
Purpose: We aimed to measure peripapillary retinal nerve fiber layer (RNFL) thickness in children with thalassemia major (tha-major), children with iron deficiency anemia (IDA), and children in a healthy control group. Materials and Methods: A total of 47 children with tha-major and 22 children with IDA were selected from two pediatric hematology outpatient clinics as our experimental groups, while 35 healthy children were randomly selected from a primary school to act as a control group. After a complete eye examination was conducted and intraocular pressure measurements were obtained, RNFL measurements were performed using optical coherence tomography, and the information was recorded for statistical analysis. Results: The mean age of the participants was 9.65 +/- 4.13 years in the tha-major group, 9.14 +/- 2.53 years in the IDA group, and 9.13 +/- 3.29 years in the control group, respectively, with no statistically significant difference among the three groups (p>0.05). Mean peripapillary RNFL thickness was 119.38 +/- 35.49 microns in the tha-major group, 184.00 +/- 31.14 microns in the IDA group, and 187.73 +/- 27.36 microns in the control group. It was significantly thinner in all quadrants in the tha-major group vs. the other two groups (p<0.01), and in only the inferior quadrant in the IDA group (p<0.05). Average RNLF thickness correlated positively with mean hemoglobin value (r = 0.488; p<0.001) and negatively with mean ferritin level (r = -0.544; p<0.001), but no correlations with mean number of transfusions and mean visual acuity were observed (p>0.05). Conclusion: The study revealed that peripapillary RNFL is thinner in tha-major in all quadrants and in only the inferior quadrant in IDA. Thinning of the RNLF correlated with hemoglobin value and ferritin level, but not with number of transfusions and visual acuity.