Browsing by Author "Atasoy, N."

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Acupuncture in Neuromuscular Lesions of Animals
(British Medical Acupuncture Society, 1999) Altug, M.E.; Tekeoglu, I.; Alkan, I.; Atasoy, N.; Keles, I.
Acupuncture treatments are described in a dog with thoracic disc herniation, a cat with spinal injury, a dog with neurological disorders caused by cerebral contusion and two cross-bred calves with spastic paresis. The beneficial effects of acupuncture are reported: notably improvements in the extensor thrust, patella and coccygeal reflexes, balance, defaecation and micturition.
Biochemistry of Lycopene
(2012) Atasoy, N.
Lycopene is a carotenoid found in foods such as tomatoes, tomato products, watermelon, pink grapefruit and guava. Lycopene provides health benefits by being absorbed into body tissues and mounting a defense against damaging free radicals that if left unchecked, create oxidative damage to cells. This leads to conditions such as cancer, heart disease, macular degeneration, diabetes, joint deterioration and accelerated aging. The body obtains antioxidants from many of the foods that comprise a healthy diet however many people fail to eat enough of these recommended foods. In addition, the city environments are overloaded with extra free radicals courtesy of sources like industrial pollution, motor vehicles and smoking. Hence, there is a need to increase the dietary intake of an effective antioxidant such as lycopene. All antioxidants have shown a role in destroying free radicals and thereby reducing the damage to all cells in the body. Lycopene inhibits free radical damage to LDL cholesterol with its antioxidant action preventing oxidation to LDL cholesterol. Oxidation of cholesterol is a process that can cause a great deal of cell damage. Lycopeneboosts the body's natural antioxidant defences and protects against DNA damage thus promotes heart health. Numerous epidemiological studies have linked diets that are high in lycopene intake with a reduced risk of cancer and degenerative diseases. This study summarizes the information about lycopene and presents the current knowledge with respect to its role in human health and disease. © Medwell Journals, 2012.
Comparison on the Effects of Some Glicosaminogylican Derives (Chitosan and Hyaluronan) in Diabetic Wound Healing
(Ataturk Universitesi, 2016) Tuygun, F.; Atasoy, N.
This study aimed to compare the effects of chitosan and hyaluronan on diabetic wounds. The study was conducted on forty New Zealand rabbits. Diabetes was created in rabbits by injection of 60mg/kg alloxan monohydrate intraperitonally twice two daysapart. Under anaesthesia, 2 cm of dimater two full thickness circular skin wounds were created on the lumbal region of all rabbits. Chitosan was aplied to one of the wounds and hyaluronan was aplied to the other wound on animals in experimental group. Wound healing were examined macroscopically and histopathologically and wound contraction rates were measured at postoperative 3th, 6th, 9th, 11th and 15th days. As a conclusion, it is determined that using chitosan in the first ten days and in the subsequent days using hyaluronan contribute positive effects on diabetic wound healing.
Determination of Heavy Metal Ions (As, Pb, Cd) and Zinc Mineral (Zn) in Human's and Cow's Milk in Bitlis (Turkey)
(Syscom 18 SRL, 2017) Aysal, H.; Atasoy, N.
Human's milk and cow's milk fed-infants, long before the mother is exposed heavy metals are potentially dangerous for both mother and baby. Concentrations of toxic heavy metals (Pb, Cd, As) and major nutritional trace element (Zn) which collected center Bitlis, Tatvan and various villages in the 75 volunteer nursing mothers received 6 months after the birth human's milks and 75 cow milks were analyzed. This study was measured by Inductively Coupled Plasma-Mass Spectrometer. Work was measured in accredited laboratory. In the samples As and Cd were under detectable leves although Zn and Pb were measured. Survey conducted, Zn and Pb levels in the mother milk which collected Tatvan borough were determined the highest. The all metal levels in the mother milk and cow milk which collected Bitlis center higher than villages. Zn levels in the cow milks which collected Bitlis center the highest. As a results of analysis, the avarege values of the lead in the human milks respectively (Bitlis center, Tatvan borough and villages) were found 0.0003±0.00004 mg/kg, 0.00045±0.000052 mg/kg, 0.0002±0.00003 mg/kg; the avarege values of the zinc 3.2±0.64 mg/ kg, 3.34±0.57 mg/kg, 2.5±0.37 mg/kg. The avarege values of the lead in the cow milks respectively (Bitlis center, Tatvan borough and villages) were found 0.002±0.0004 mg/kg, 0.003±0.0004 mg/kg, 0.001±0.0003 mg/kg; the avarege values of the zinc 3.7±0.51 mg/kg, 3.6±0.49 mg/kg, 3.0±0.41 mg/kg. As a results of analysis between groups weren't found significant relationship (P>0.05).
Determination of the Amount of Certain Heavy Metal Ions and Some Specific Liver Enzymes and Levels of Testesterone Hormone in the Blood Sera of Heavy Asphalt Workers and Rural Community in Van, Turkey
(2011) Atasoy, N.; Kanat, Y.
In the present study, the effects of heavy metals Lead (Pb), Cadmium (Cd) on the liver enzymes Glutamate Oxalate Transaminase (GOT), Glutamic Pyruvate Transaminase (GPT) and testosterone hormone concentration heavy asphalt workers were investigated. Research material consists of blood samples taken from Van highway asphalt workers and rural community (Bardakci). The research was conducted with attention paid to personal traits. Results of lead, cadmium, enzyme activities and hormone content in the blood samples of workers and rural people are interpreted by variance analysis with uni-variety method in Spss package software. According to the results, GOT amount in highway asphalt workers was 23.27±1.09 U L-1 while it was 23.82±1.75 U L-1, GPT amount in highway asphalt workers was 23.82±1.75 U L-1 while it was 20.48±1.61 U L-1 in the control group. Pb amount was significant at the rate of 14.64±0.64 μg/100 mL in asphalt workers and 5.04±0.60 ug/100 mL and p<0.01 in the control group; Cd amount was significant at the rate of 0.16LL0.028 μg/100 mL in the asphalt workers and 0.038±0.026 ug/100 mL and p<0.01 in the control group with the amounts and significance as 0.283±0.032 μg/100 mL in smoking workers and 0.038±0.021 μg/100 mL and p<0.01 in non-smoking workers; the amount and significance of testosterone was found as 631.38±41.09 ng dL-1 in non-smoking asphalt workers and 388.65±29.05 and p<0.01 in smoking workers; the amount of testosterone in non-smoking asphalt workers was 657.38±36.04 and 450.05±30.63 dL-1 in smoking asphalt workers with p<0.01 significance. © Medwell Journals, 2011.
Evaluate the Effects of Platelet Rich Plasma (Prp) and Zinc Oxide Ointment on Skin Wound Healing
(Elsevier Ltd, 2019) Abdullah, B.J.; Atasoy, N.; Omer, A.K.
In this study efficiency of platelet rich plasma (PRP) and zinc oxide on full thickness wounds created on rabbits was researched. This study conducted on 24 New Zealand rabbits divided 2 groups. A circular of 1.5 × 1.5 cm (2.5 cm2) full thickness skin wound was created under the general anesthesia. 1 ml PRP (5.503106/mm3) was applied to the one of the wounds subcutaneously. To the other wound 1 mm3 zinc oxide ointment was applied once a day during the study. Wound contraction rates were measured, biopsy materials were collected and evaluated macroscopically and histopathologically postoperatively 3rd, 7th and 15th days. As a result it is determined that PRP and zinc oxide accelerated wound contraction rates between the groups were determined as 3rd day p = 0.007, 7th day p = 0.0002 and 15th day p = 0.002. © 2018 The Author(s)
Evaluation of a Mixture of Thiopental-Guafinesine and Sevoflurane Anesthesia in Horses
(Academic Journals inc, 2009) Atasoy, N.; Mercan, N.; Atalay, C.; Bayram, E.; Tas, A.
The anesthetic and cardiopulmonary effects of a combination of continuous intravenous infusion using a mixture of 6 g L-1 thiopental-75 g L-1 guafinesine-3 mg L-1 metedomidine (0.30 mL/kg/h) and Oxygen-Sevoflurane (OS) anesthesia (TGM-OS anesthesia) in horses were evaluated. The concentration of sevoflurane (Sevo) required maintaining surgical anesthesia was around 1.5% in TGM-OS and 3.3% in OS anesthesia. Mean Arterial Blood Pressure (MABP) was maintained at around 77 mm Hg under TGMOS anesthesia, while dobutamine (0.43 +/- 0.13 mu g kg(-1)) infusion was necessary to maintain MABP at 60 mmHg under OS anesthesia. No apparent complication was observed during and after anesthesia in all cases. Recovery from anesthesia tinder TGM-OS anesthesia was very calm and smooth. The times required for the horse to return both sternal and standing position in group under TGM-OS anesthesia tended to be shorter than group under OS anesthesia which statistical differences were p<0.05 and p<0.01, respectively. Thiopental Guafinesine-Metedomidine and Oxygen-Sevoflurane anesthesia (TGM-OS anesthesia) may be useful for prolonged equine anesthesia because of its minimal cardiopulmonary effects and good recovery from anesthesia.
Evaluation of Analgesic and Anti Inflammatory Activity of Pimpinella Anisum Fixed Oil Extract
(indian veterinary Journal, 2006) Tas, A.; Ozbek, H.; Atasoy, N.; Altug, M. Enes; Ceylan, E.
Pimpinella anisum is a member of the Umbelliferae and is found in the northeastern Anatolia (Zeybek, 1960). In Turkish folk medicine, Pimpinella species have several uses such. as analgesic, anti-inflammatory, appetizing, hypnotic, antispasmodic, expectorant,. antibacterial and hepato-protective. Seeds of P. anisum contains 1.5 - 2.0 % essential oil, 10-20 % fixed oil, 18 % protein. No reports are available on the evaluation of this plant for possible anti-inflammatory and analgesic activity: In this study, fixed oil of P. anisum was investigated for anti-inflammatory activity using carrageenan-induced rat paw oedema test (Winter et al., 1962) and analgesic activity with a tail-flick apparatus using a method initially described by D'amour and Smith (1941).
Histopathological and Immunohistochemical Study of the Effect of Sildenafil Citrate, Vitamin A, Vitamin C and Vitamin E on Wound Healing in Alloxan-Induced Diabetic Rats
(Univ West indies Faculty Medical Sciences, 2021) Tas, A.; Karasu, A.; Yener, Z.; Yildirim, S.; Atasoy, N.; Duz, E.; Yavuz, E.
Objective: To examine the impact of sildenafil citrate, vitamin A (Vit A), vitamin C (Vt C) and vitamin E (Vit E) on wound healing in a rat model of diabetes (n = 100). Methods: Diabetes was induced in the rats by intraperitoneal (i.p.) administration of alloxan. After anaesthesia, a standard wound was created on the back of each rat using a 10-mm sterile punch. The rats were randomly divided into 10 groups (n = 10 in each), as follows: normal saline, glibenclamide, insulin, sildenafil, Vit A, Vit C, Vit E, Vit A + sildenafil, Vit C + sildenafil, Vit E + sildenafil daily for 15 days. The rats were sacrificed after being anaesthetized 3, 7 and 15 days later Wounded skin tissue samples were collected for histopathological and immunohistochemical analyses. Results: On the 7th day, epithelial regeneration was completed in groups 8 and 9. Angiogenesis was insufficient in group 2. In terms of connective tissue proliferation, partially matured connective tissue was observed in group 4. On the 15th day of the study, groups 8, 9 and 10 had mature connective tissue. However; group 1 still had exudate-containing neutrophils. Immunohistochemically, on the 3rd day, the level of inducible nitric oxide synthase (iNOS) reactivity was intense in macrophages and neutrophils surrounding the wound edges in groups 4, 8, 9 and 10. The level of iNOS reactivity was moderate in group 6 and less distinct in groups 1, 2, 3, 5 and 7. Conclusion: Sildenafil citrate, together with Vit A and Vit C, is beneficial in wound healing of diabetic rats.
Köpeklerde Prostatın Ultrasonografik ve Radyografik Bulgularının Karşılaştırılması
(2000) Atasoy, N.; Alkan, İ.; Aslan, L.; Gençcelep, M.; Bakır, B.
Bu çalışmada 2-7 yaş arasında 3'ü prostatomegali'li, 17' si sağlıklı 20 adet erkek melez köpek kullanıldı. Radyolojik tetkiklerden ultrasanografik muayene; B-mode, real time, 5.0 MHz'lik sektör prob'lu cihazla, radyografi ise direki, negatif ve pozitif kontrast teknikleriyle gerçekleştirildi. Direkt veya negatif kontrast tekniklerde prostat bezinin simetrisini belirlemek için üretraya radyoopak kateter yerleştirildi. Radyografiyle yalnız pelvik çatının kranialinde bulunan prostat bezlerinin görüntüleri alına-bilirken pelvik çatı içerisindeki bezlerin görüntülerinin probun kaudale doğ%Ujaçılandınlmasıyla alınması ultra-sonografinin avantajı Aarak değerlendirildi. Prostatomegali; bez boyutlarındaki artışın ultrasonografi ve radyografi ile belirlenmesiyle tespit edildi ve klinik*^ muayene yöntemleriyle de desteklendi.
Nitrate and Nitrite Levels of Natural Spring and Mineral Water in Van, Turkey
(2011) Atasoy, N.; Alemdar, S.; Mercan, U.; Agaoglu, S.
This study was performed to determine nitrate and nitrite levels of packaged natural spring and mineral water consumed in Van city of Turkey. A total of 200 water samples, belonging to 10 different companies, each of 100 pet spring water and 100 bottled mineral water samples were used as material. Nitrate and nitrite levels were measured by the spectrophotometric method. According to the results both nitrate and nitrite were found to be present in all water samples. Mean nitrate and nitrite concentrations were 3.66±0.028 and 0.045±0.003 mg L-1 in the spring water and 3.52±0.011 and 0.025±0.001 mg L-1 in the mineral water, respectively. Finally; nitrate and nitrite levels in water samples were in accordance with the related national and international regulations and considered safe for consuming. © Medwell Journals, 2011.
Pseudopericarditis in a Cow Caused by Theileriosis - a Case Report
(2003) Keleş, I.; Alptekin, I.; Atasoy, N.; Çinar, A.; Dönmez, N.; Ceylan, E.
Pseudopericarditis has been used to describe jugular engorgement and oedema of the brisket and ventral abdominal wall. Similar symptoms can be seen in cattle with traumatic pericarditis. Pressure caused by tumours, abscesses, Echinococcus cysts, swollen lymph nodes resulting from tuberculosis and leukosis, one-sided pleuritis and diaphragmatic hernia to the base of cranial and caudal vena cava returning blood to the heart have been reported to cause pseudopericarditis in cattle. These mediastinal lymph nodes may also be swollen due to theileriosis and cause pressure on the v. cava. This study aims to describe the clinical, haematological and electrocardiographical findings of a pseudopericarditis case in a cow caused by theileriosis, and to add the disease into the aetiology of pseudopericarditis.